Cited 2 times in
Impact of cholecystectomy on acute coronary syndrome according to metabolic condition: a nationwide population-based cohort study
DC Field | Value | Language |
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dc.contributor.author | 박승우 | - |
dc.contributor.author | 박정엽 | - |
dc.contributor.author | 방승민 | - |
dc.contributor.author | 이희승 | - |
dc.contributor.author | 장성인 | - |
dc.contributor.author | 정문재 | - |
dc.contributor.author | 조중현 | - |
dc.contributor.author | 채원정 | - |
dc.contributor.author | 송시영 | - |
dc.date.accessioned | 2023-07-12T03:12:34Z | - |
dc.date.available | 2023-07-12T03:12:34Z | - |
dc.date.issued | 2023-05 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/195538 | - |
dc.description.abstract | Gallbladder stones (GS) is associated with an increased risk of cardiovascular disease. However, the relationship between cholecystectomy for GS and acute coronary syndrome (ACS) is unknown. We investigated the ACS risk in patients with GS and its association with cholecystectomy. Data from the Korean National Health Insurance Service-National Sample Cohort from 2002 to 2013 was extracted. Overall, 64,370 individuals were selected through a 1:3 propensity score matching. Patients were stratified into two groups for comparison: the gallstone group, GS patients with or without cholecystectomy; and the control group, patients without GS or cholecystectomy. The gallstone group exhibited a higher risk of ACS than the control group (hazard ratio [HR], 1.30; 95% confidence interval [CI] 1.15–1.47; P < 0.0001). In the gallstone group, individuals without cholecystectomy had a higher risk of ACS development (HR: 1.35, 95% CI 1.17–1.55, P < 0.0001). Patients with GS with diabetes, hypertension, or dyslipidemia, had a higher risk of developing ACS than GS patients without the metabolic diseases (HR: 1.29, P < 0.001). The risk did not significantly differ after cholecystectomy compared to those without GS (HR: 1.15, P = 0.1924), but without cholecystectomy, the risk of ACS development was significantly higher than control group (1.30, 95% CI 1.13–1.50, P = 0.0004). Among patients without above metabolic disorders, cholecystectomy was still associated with increased ACS risk in the gallstone group (HR: 2.93, 95% CI 1.27–6.76, P = 0.0116). GS increased the risk of ACS. The effect of cholecystectomy on ACS risk differs according to the presence or absence of metabolic disorders. Thus, the decision to perform cholecystectomy for GS should consider both the ACS risk and the underlying disorders. © 2023, The Author(s). | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Nature Publishing Group | - |
dc.relation.isPartOf | SCIENTIFIC REPORTS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Acute Coronary Syndrome* / complications | - |
dc.subject.MESH | Acute Coronary Syndrome* / epidemiology | - |
dc.subject.MESH | Acute Coronary Syndrome* / surgery | - |
dc.subject.MESH | Cholecystectomy / adverse effects | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Diabetes Mellitus* | - |
dc.subject.MESH | Gallstones* / complications | - |
dc.subject.MESH | Gallstones* / epidemiology | - |
dc.subject.MESH | Gallstones* / surgery | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Risk Factors | - |
dc.title | Impact of cholecystectomy on acute coronary syndrome according to metabolic condition: a nationwide population-based cohort study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Wonjeong Chae | - |
dc.contributor.googleauthor | Hee Seung Lee | - |
dc.contributor.googleauthor | Jung Hyun Jo | - |
dc.contributor.googleauthor | Moon Jae Chung | - |
dc.contributor.googleauthor | Seungmin Bang | - |
dc.contributor.googleauthor | Seung Woo Park | - |
dc.contributor.googleauthor | Si Young Song | - |
dc.contributor.googleauthor | Sung-In Jang | - |
dc.contributor.googleauthor | Jeong Youp Park | - |
dc.identifier.doi | 10.1038/s41598-023-33440-4 | - |
dc.contributor.localId | A01551 | - |
dc.contributor.localId | A01647 | - |
dc.contributor.localId | A01786 | - |
dc.contributor.localId | A03349 | - |
dc.contributor.localId | A03439 | - |
dc.contributor.localId | A03602 | - |
dc.contributor.localId | A03912 | - |
dc.relation.journalcode | J02646 | - |
dc.identifier.eissn | 2045-2322 | - |
dc.identifier.pmid | 37147417 | - |
dc.contributor.alternativeName | Park, Seung Woo | - |
dc.contributor.affiliatedAuthor | 박승우 | - |
dc.contributor.affiliatedAuthor | 박정엽 | - |
dc.contributor.affiliatedAuthor | 방승민 | - |
dc.contributor.affiliatedAuthor | 이희승 | - |
dc.contributor.affiliatedAuthor | 장성인 | - |
dc.contributor.affiliatedAuthor | 정문재 | - |
dc.contributor.affiliatedAuthor | 조중현 | - |
dc.citation.volume | 13 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 7300 | - |
dc.identifier.bibliographicCitation | SCIENTIFIC REPORTS, Vol.13(1) : 7300, 2023-05 | - |
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