거대세포종의 임상적 고찰

Abstract

The giant cell tumor is an rather common primary bone tumor of young adult 20 to 40 years of age, most frequently found around the knee joint and the distal end of the radius. So the normal life expectancy and the active life style of patient necessitate a reliable and durable surgical remedy for eradicating the tumor and preserving joint function. Although almost are benign, sometimes these tumors are locally invasive and tend to have a high rate of recurrence, and malignant transformation is well known. Thus, a satisfactory method of treatment has not yet be found. Clinical observation were carried out on 44 cases of giant cell tumor of bone in the department of Orthopedic Surgery, Yonsei University College of Medicine from January 1981 through November 1991. Mean follow-up period was 2 years and 9 months. The age incidence was most frequent in third decade (50.0%), with male predominence as a whole. Usual location of the lesion was around the knee(70.5%). The recurrence rate for total cases was 25%: 46.2% after curettage and bone graft ; 25% after curettage and bone cement filling : no recurrence after segmental resection and replantation or amputation. We analyzed the recurrence rate according to the Jaffe s pathologic grades. It looked like higher incidence of local recurrence with higher grade. But due to the small number of patients and short follow-up, we need more cases and follow-up. The local recurrence was noted even after 2 years postoperatively, long term fol low-up is need to find it.