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Corticobasal degeneration. A clinical study of 36 cases
DC Field | Value | Language |
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dc.contributor.author | 이명식 | - |
dc.date.accessioned | 2023-07-12T00:13:54Z | - |
dc.date.available | 2023-07-12T00:13:54Z | - |
dc.date.issued | 1994-10 | - |
dc.identifier.issn | 0006-8950 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/194955 | - |
dc.description.abstract | The presenting features and their subsequent evolution in 36 patients with pathologically proven or clinically probable corticobasal degeneration are described. The most common initial complaint was of a unilateral 'clumsy, stiff or jerky arm' (n = 20). Typically the arm was akinetic, rigid and apraxic. In about a third of these the arm was held in a striking and characteristic fixed dystonic posture. Jerking of the arm, due to action and stimulus-sensitive myoclonus accompanied these symptoms in about a third of the cases. The next most common presentation (n = 10) was difficulty walking due to clumsiness and loss of fine motor control of one leg due to apraxia or dysequilibrium, or a combination of both. Sensory symptoms in the affected arm heralded the onset of illness in three and accompanied a motor disturbance in two cases. Presentation with dysarthria or a behavioural syndrome were rare. The symptoms progressed slowly, usually involving first the ipsilateral arm and leg, but gradually spread to affect all four limbs. After a mean follow-up of 5.2 years (range 2-8 years) gait difficulties and a supranuclear ophthalmoplegia had emerged in most patients and dysarthria and pyramidal signs were common. Higher mental function was relatively preserved in most and a cortical sensory loss was evident in a quarter of cases. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Oxford University Press | - |
dc.relation.isPartOf | BRAIN | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Brain Diseases / physiopathology* | - |
dc.subject.MESH | Cerebral Cortex / physiopathology* | - |
dc.subject.MESH | Dementia / diagnosis | - |
dc.subject.MESH | Diagnosis, Differential | - |
dc.subject.MESH | Dystonia / physiopathology | - |
dc.subject.MESH | Extremities / physiopathology* | - |
dc.subject.MESH | Eye Movements | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Gait | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Movement Disorders / diagnosis | - |
dc.subject.MESH | Movement Disorders / physiopathology* | - |
dc.subject.MESH | Myoclonus / physiopathology | - |
dc.subject.MESH | Parkinson Disease / diagnosis | - |
dc.subject.MESH | Postural Balance | - |
dc.title | Corticobasal degeneration. A clinical study of 36 cases | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurology (신경과학교실) | - |
dc.contributor.googleauthor | J. O. Rinne | - |
dc.contributor.googleauthor | M. S. Lee | - |
dc.contributor.googleauthor | P. D. Thompson | - |
dc.contributor.googleauthor | C. D. Marsden | - |
dc.identifier.doi | 10.1093/brain/117.5.1183 | - |
dc.contributor.localId | A02753 | - |
dc.relation.journalcode | J00385 | - |
dc.identifier.eissn | 1460-2156 | - |
dc.identifier.pmid | 7953598 | - |
dc.identifier.url | https://academic.oup.com/brain/article/117/5/1183/362361 | - |
dc.contributor.alternativeName | Lee, Myung Sik | - |
dc.contributor.affiliatedAuthor | 이명식 | - |
dc.citation.volume | 117 | - |
dc.citation.number | Pt 5 | - |
dc.citation.startPage | 1183 | - |
dc.citation.endPage | 1196 | - |
dc.identifier.bibliographicCitation | BRAIN, Vol.117(Pt 5) : 1183-1196, 1994-10 | - |
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