Cited 2 times in
Adherence to healthy lifestyle behaviors as a preventable risk factor for severe hypoglycemia in people with type 2 diabetes: A longitudinal nationwide cohort study
DC Field | Value | Language |
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dc.contributor.author | 이용호 | - |
dc.date.accessioned | 2023-06-02T00:39:39Z | - |
dc.date.available | 2023-06-02T00:39:39Z | - |
dc.date.issued | 2022-09 | - |
dc.identifier.issn | 2040-1116 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/194335 | - |
dc.description.abstract | Aims/introduction: We investigated the associations between a combination of lifestyle factors and changes to these factors and the subsequent risk of severe hypoglycemia (SH) in type 2 diabetes patients. Materials and methods: Individuals with adult type 2 diabetes who underwent consecutive 2-year interval health screening programs from 2009 to 2012 from the Korean National Health Insurance Service database were included and followed up until 2018. Information on history of smoking status, alcohol consumption and physical activity, as well as changes to these factors, was obtained. The primary outcome was incident SH. Results: Of the 1,490,233 type 2 diabetes patients, 30,539 (2.1%) patients developed SH. Current smokers and heavy drinkers had increased risk of SH, compared with non-smokers and non-drinkers, respectively (hazard ratio 1.28, 95% confidence interval 1.23-1.34; hazard ratio 1.22, 95% confidence interval 1.15-1.30). However, regular physical activity was associated with reduced SH risk (hazard ratio 0.79, 95% confidence interval 0.77-0.82). A combination of unhealthy lifestyle habits was associated with increased SH risk in a dose-dependent fashion (P for trend <0.001). Compared with participants without changes in their unhealthy lifestyles, participants who improved lifestyles had decreased risk of SH. Conclusions: Greater adherence to healthy lifestyle factors and any improvement in unhealthy lifestyle habits were associated with a substantially lower risk of SH in individuals with type 2 diabetes. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Asian Association for the Study of Diabetes and Blackwell Pub. Asia | - |
dc.relation.isPartOf | JOURNAL OF DIABETES INVESTIGATION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Diabetes Mellitus, Type 2* / complications | - |
dc.subject.MESH | Diabetes Mellitus, Type 2* / epidemiology | - |
dc.subject.MESH | Healthy Lifestyle | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypoglycemia* / complications | - |
dc.subject.MESH | Hypoglycemia* / epidemiology | - |
dc.subject.MESH | Hypoglycemia* / prevention & control | - |
dc.subject.MESH | Risk Factors | - |
dc.title | Adherence to healthy lifestyle behaviors as a preventable risk factor for severe hypoglycemia in people with type 2 diabetes: A longitudinal nationwide cohort study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Jae-Seung Yun | - |
dc.contributor.googleauthor | Kyungdo Han | - |
dc.contributor.googleauthor | Yong-Moon Park | - |
dc.contributor.googleauthor | Eugene Han | - |
dc.contributor.googleauthor | Yong-Ho Lee | - |
dc.contributor.googleauthor | Seung-Hyun Ko | - |
dc.identifier.doi | 10.1111/jdi.13818 | - |
dc.contributor.localId | A02989 | - |
dc.relation.journalcode | J01377 | - |
dc.identifier.eissn | 2040-1124 | - |
dc.identifier.pmid | 35474300 | - |
dc.subject.keyword | Diabetes, type 2 | - |
dc.subject.keyword | Lifestyle behavior | - |
dc.subject.keyword | Severe hypoglycemia | - |
dc.contributor.alternativeName | Lee, Yong Ho | - |
dc.contributor.affiliatedAuthor | 이용호 | - |
dc.citation.volume | 13 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 1533 | - |
dc.citation.endPage | 1542 | - |
dc.identifier.bibliographicCitation | JOURNAL OF DIABETES INVESTIGATION, Vol.13(9) : 1533-1542, 2022-09 | - |
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