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A Retrospective National Study on Colonization Rate and Antimicrobial Susceptibility of Streptococcus agalactiae in Pregnant Korean Women, 2018-2020
DC Field | Value | Language |
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dc.contributor.author | 이경원 | - |
dc.date.accessioned | 2023-06-02T00:38:46Z | - |
dc.date.available | 2023-06-02T00:38:46Z | - |
dc.date.issued | 2022-08 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/194327 | - |
dc.description.abstract | Purpose: The prevalence of Group B Streptococcus (GBS) colonization in pregnant Korean women is increasing; however, nationwide studies are lacking. Therefore, we aimed to analyze regional colonization rates and antimicrobial susceptibility for GBS in pregnant Korean women through a nationwide survey. Materials and methods: From January 2018 to December 2020, data from the Seoul Clinical Laboratories on vaginal swab cultures were retrospectively analyzed to detect maternal GBS carriers. Each swab specimen was inoculated onto a 5% blood agar plate and incubated at 35℃-37℃ in a 5% CO2 incubator for 24 h. GBS isolates were identified using a Microflex MALDI Biotyper. Antimicrobial susceptibility tests were performed using the Vitek 2 automated system. Results: The overall nationwide GBS colonization rate in pregnant Korean women was found to be 10.6% (3578/33721). The maternal GBS colonization rates ranged from 10.5%-10.8% over the 3-year study period. The GBS colonization rates by province, in descending order, were as follows: Jeolla-do, 13.2%; Gangwon-do, 12.0%; Chungcheong-do, 11.8%; Gyeonggi-do, 11.3%; Seoul, 10.2%; and Gyeongsang-do, 9.6%. During the study period, the resistance rates against chloramphenicol, levofloxacin, clindamycin, erythromycin, and tetracycline were 2.6%-2.7%, 18.2%-19.6%, 33.4%-35.7%, 35.6%-36.8%, and 50.5%-53.3%, respectively. Conclusion: In pregnant Korean women, GBS colonization rates were in the range of 9.6%-13.2%, with Gyeongsang-do being the lowest and Jeolla-do the highest. The resistance rate against clindamycin was high (33.4%-35.7%). GBS colonization rates during pregnancy should be studied nationwide according to the Centers for Disease Control and Prevention-recommended guidelines with periodic antimicrobial resistance monitoring. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Yonsei University | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Anti-Bacterial Agents / pharmacology | - |
dc.subject.MESH | Anti-Bacterial Agents / therapeutic use | - |
dc.subject.MESH | Clindamycin / pharmacology | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Microbial Sensitivity Tests | - |
dc.subject.MESH | Pregnancy | - |
dc.subject.MESH | Pregnancy Complications, Infectious* / drug therapy | - |
dc.subject.MESH | Pregnancy Complications, Infectious* / epidemiology | - |
dc.subject.MESH | Republic of Korea / epidemiology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Streptococcus agalactiae* | - |
dc.subject.MESH | Vagina | - |
dc.title | A Retrospective National Study on Colonization Rate and Antimicrobial Susceptibility of Streptococcus agalactiae in Pregnant Korean Women, 2018-2020 | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학교실) | - |
dc.contributor.googleauthor | Hye Gyung Bae | - |
dc.contributor.googleauthor | Jungmi Hong | - |
dc.contributor.googleauthor | Young-Jin Kim | - |
dc.contributor.googleauthor | Kyoung-Ryul Lee | - |
dc.contributor.googleauthor | Kyungwon Lee | - |
dc.contributor.googleauthor | Seong Jin Choi | - |
dc.contributor.googleauthor | Young Uh | - |
dc.identifier.doi | 10.3349/ymj.2022.63.8.717 | - |
dc.contributor.localId | A02649 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 35914753 | - |
dc.subject.keyword | Group B Streptococcus | - |
dc.subject.keyword | clindamycin | - |
dc.subject.keyword | erythromycin | - |
dc.subject.keyword | pregnant women | - |
dc.contributor.alternativeName | Lee, Kyungwon | - |
dc.contributor.affiliatedAuthor | 이경원 | - |
dc.citation.volume | 63 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 717 | - |
dc.citation.endPage | 723 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.63(8) : 717-723, 2022-08 | - |
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