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혀에 발생한 전이성 미분화다형태육종 증례 보고

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dc.contributor.author김현실-
dc.contributor.author김형준-
dc.contributor.author홍진호-
dc.date.accessioned2023-04-07T01:18:58Z-
dc.date.available2023-04-07T01:18:58Z-
dc.date.issued2022-10-
dc.identifier.issn1225-1577-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/193877-
dc.description.abstractSarcoma is rare malignant tumors that develop from mesenchymal cells. Metastasis to the oral cavity is a rare occurrence. Undifferentiated Pleomorphic sarcoma(UPS), formerly known as Malignant fibrous histiocytoma(MFH), is rare spindle cell neoplasm that can have poorly prognosis with metastasis and local recurrence. This report describes a case of a 77-year-old man who was diagnosed with Undifferentiated Pleomorphic Sarcoma of the chest wall and underwent adjuvant radiation therapy after surgical resection. Although there was success of wide excision, two years later, he presented with metastasis to the several organs including tongue. We retrospectively analyzed results of Next Generation Sequencing(NGS), and we figured out RB1 gene mutation. Until now targeted therapy of RB1 gene mutation is not established. Surgeon needs to consider metastatic tumors through identifying patients’ chief complaints and past medical & dental history. We need to research through NGS, and take a step closer to find targeted therapy for tumors.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageKorean-
dc.publisher대한구강악안면병리학회-
dc.relation.isPartOfKorean Journal of Oral and Maxillofacial Pathology(대한구강악안면병리학회지)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.title혀에 발생한 전이성 미분화다형태육종 증례 보고-
dc.title.alternativeMetastatic Undifferentiated Pleomorphic Sarcoma on Tongue: Case Report-
dc.typeArticle-
dc.contributor.collegeCollege of Dentistry (치과대학)-
dc.contributor.departmentDept. of Oral Pathology (구강병리학교실)-
dc.contributor.googleauthor김윤현-
dc.contributor.googleauthor홍진호-
dc.contributor.googleauthor정재환-
dc.contributor.googleauthor한승용-
dc.contributor.googleauthor김현실-
dc.contributor.googleauthor김형준-
dc.identifier.doi10.17779/KAOMP.2022.46.5.005-
dc.contributor.localIdA01121-
dc.contributor.localIdA01156-
dc.relation.journalcodeJ02084-
dc.subject.keywordUPS-
dc.subject.keywordUndifferentiated Pleomorphic Sarcoma-
dc.subject.keywordRB1-
dc.subject.keywordTongue metastasis-
dc.subject.keywordMetastatic sarcoma-
dc.contributor.alternativeNameKim, Hyun Sil-
dc.contributor.affiliatedAuthor김현실-
dc.contributor.affiliatedAuthor김형준-
dc.citation.volume46-
dc.citation.number5-
dc.citation.startPage105-
dc.citation.endPage109-
dc.identifier.bibliographicCitationKorean Journal of Oral and Maxillofacial Pathology(대한구강악안면병리학회지), Vol.46(5) : 105-109, 2022-10-
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Oral Pathology (구강병리학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Oral and Maxillofacial Surgery (구강악안면외과학교실) > 1. Journal Papers

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