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Seroprevalence of severe acute respiratory syndrome coronavirus 2 antibodies during the third wave of coronavirus disease in the Seoul metropolitan area of Korea

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dc.contributor.author이혁민-
dc.date.accessioned2023-04-07T01:14:54Z-
dc.date.available2023-04-07T01:14:54Z-
dc.date.issued2022-09-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/193842-
dc.description.abstractObjectives: After the third wave of coronavirus disease (COVID-19), by mid-February 2021, approximately 0.16% of the population was confirmed positive, which appeared to be one of the lowest rates worldwide at that time. However, asymptomatic transmission poses a challenge for COVID-19 surveillance. Therefore, a community-based serosurvey of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was conducted to understand the effectiveness of Korea's strong containment strategy. Methods: We collected 5,002 residual sera samples from January 30 to March 3, 2021 from 265 medical facilities in Seoul, 346 in Kyunggi-do' and 57 in Incheon. Among them, 60 samples from tertiary institutions were excluded. We defined the sub-regions according to the addresses of the medical facilities where the specimens were collected. Elecsys Anti-SARS-CoV-2 was used for the screening test, and positivity was confirmed using the SARS-CoV-2 sVNT Kit. Prevalence was estimated using sampling weight and the Wilson score interval for a binomial proportion with a 95% confidence interval. Results: Among the 4,942 specimens, 32 and 25 tested positive for COVID-19 in the screening and confirmatory tests, respectively. The overall crude prevalence of SARS-CoV-2 antibody was 0.51%. The population-adjusted overall prevalence was 0.55% in women and 0.38% in men. The region-specific estimation was 0.67% and 0.30% in Gyeonggi-do and Seoul, respectively. No positive cases were detected in Incheon. Conclusion: The proportion of undetected cases in South Korea remains low. Therefore, an infection control strategy with exhaustive tracing and widespread pre-emptive testing appears to be effective in containing the spread of the virus in the community.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKorean Society of Epidemiology-
dc.relation.isPartOfEPIDEMIOLOGY AND HEALTH-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleSeroprevalence of severe acute respiratory syndrome coronavirus 2 antibodies during the third wave of coronavirus disease in the Seoul metropolitan area of Korea-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학교실)-
dc.contributor.googleauthorKyuhyun Yoon-
dc.contributor.googleauthorJayeun Kim-
dc.contributor.googleauthorKyong Ran Peck-
dc.contributor.googleauthorHyun Soo Kim-
dc.contributor.googleauthorHyukmin Lee-
dc.contributor.googleauthorYoo-Sung Hwang-
dc.contributor.googleauthorSoon Young Lee-
dc.contributor.googleauthorSung-Il Cho-
dc.contributor.googleauthorHun Jae Lee-
dc.contributor.googleauthorYeongyeong Kim-
dc.contributor.googleauthorBrian Byoungguk Kim-
dc.contributor.googleauthorJune-Woo Lee-
dc.contributor.googleauthorAh-Ra Kim-
dc.contributor.googleauthorHyeonNam Do-
dc.contributor.googleauthorDong-Hyun Kim-
dc.identifier.doi10.4178/epih.e2022085-
dc.contributor.localIdA03286-
dc.relation.journalcodeJ00791-
dc.identifier.eissn2092-7193-
dc.identifier.pmid36228670-
dc.subject.keywordAsymptomatic-
dc.subject.keywordCoronavirus disease-
dc.subject.keywordCumulative incidence-
dc.subject.keywordSeroprevalence-
dc.subject.keywordSevere acute respiratory syndrome coronavirus 2-
dc.contributor.alternativeNameLee, Hyuk Min-
dc.contributor.affiliatedAuthor이혁민-
dc.citation.volume44-
dc.citation.startPagee2022085-
dc.identifier.bibliographicCitationEPIDEMIOLOGY AND HEALTH, Vol.44 : e2022085, 2022-09-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

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