Cited 5 times in
Effectiveness and safety of EVT in patients with acute LVO and low NIHSS
DC Field | Value | Language |
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dc.contributor.author | 유준상 | - |
dc.date.accessioned | 2023-04-07T01:13:09Z | - |
dc.date.available | 2023-04-07T01:13:09Z | - |
dc.date.issued | 2022-08 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/193821 | - |
dc.description.abstract | Background and purpose: There is much uncertainty in endovascular treatment (EVT) decisions in patients with acute large vessel occlusion (LVO) and mild neurological deficits. Methods: From a prospective, nationwide stroke registry, all patients with LVO and baseline NIHSS <6 presenting within 24 h from the time last known well (LKW) were included. Early neurological deterioration (END) developed before EVT was prospectively collected as an increasing total NIHSS score ≥2 or any worsening of the NIHSS consciousness or motor subscores during hospitalization not related to EVT. Significant hemorrhage was defined as PH2 hemorrhagic transformation or hemorrhage at a remote site. The modified Rankin Scale (mRS) was prospectively collected at 3 months. Results: Among 1,083 patients, 149 (14%) patients received EVT after a median of 5.9 [3.6-12.3] h after LKW. In propensity score-matched analyses, EVT was not associated with mRS 0-1 (matched OR 0.99 [0.63-1.54]) but increased the risk of a significant hemorrhage (matched OR, 4.51 [1.59-12.80]). Extraneous END occurred in 207 (19%) patients after a median of 24.5 h [IQR, 13.5-41.9 h] after LKW (incidence rate, 1.41 [95% CI, 1.23-1.62] per 100 person-hours). END unrelated to EVT showed a tendency to modify the effectiveness of EVT (P-for-interaction, 0.08), which decreased the odds of having mRS 0-1 in mild LVO patients without END (adjusted OR, 0.63 [0.40-0.99]). Conclusions: The use of EVT in patients with acute LVO and low NIHSS scores may require the assessment of individual risks of early deterioration, hemorrhagic complications and expected benefit. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Frontiers Research Foundation | - |
dc.relation.isPartOf | FRONTIERS IN NEUROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Effectiveness and safety of EVT in patients with acute LVO and low NIHSS | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurology (신경과학교실) | - |
dc.contributor.googleauthor | Beom Joon Kim | - |
dc.contributor.googleauthor | Bijoy K Menon | - |
dc.contributor.googleauthor | Joonsang Yoo | - |
dc.contributor.googleauthor | Jung Hoon Han | - |
dc.contributor.googleauthor | Bum Joon Kim | - |
dc.contributor.googleauthor | Chi Kyung Kim | - |
dc.contributor.googleauthor | Jae Guk Kim | - |
dc.contributor.googleauthor | Joon-Tae Kim | - |
dc.contributor.googleauthor | Hyungjong Park | - |
dc.contributor.googleauthor | Sung Hyun Baik | - |
dc.contributor.googleauthor | Moon-Ku Han | - |
dc.contributor.googleauthor | Jihoon Kang | - |
dc.contributor.googleauthor | Jun Yup Kim | - |
dc.contributor.googleauthor | Keon-Joo Lee | - |
dc.contributor.googleauthor | Jong-Moo Park | - |
dc.contributor.googleauthor | Kyusik Kang | - |
dc.contributor.googleauthor | Soo Joo Lee | - |
dc.contributor.googleauthor | Jae-Kwan Cha | - |
dc.contributor.googleauthor | Dae-Hyun Kim | - |
dc.contributor.googleauthor | Jin-Heon Jeong | - |
dc.contributor.googleauthor | Tai Hwan Park | - |
dc.contributor.googleauthor | Sang-Soon Park | - |
dc.contributor.googleauthor | Kyung Bok Lee | - |
dc.contributor.googleauthor | Jun Lee | - |
dc.contributor.googleauthor | Keun-Sik Hong | - |
dc.contributor.googleauthor | Yong-Jin Cho | - |
dc.contributor.googleauthor | Hong-Kyun Park | - |
dc.contributor.googleauthor | Byung-Chul Lee | - |
dc.contributor.googleauthor | Kyung-Ho Yu | - |
dc.contributor.googleauthor | Mi-Sun Oh | - |
dc.contributor.googleauthor | Dong-Eog Kim | - |
dc.contributor.googleauthor | Wi-Sun Ryu | - |
dc.contributor.googleauthor | Kang-Ho Choi | - |
dc.contributor.googleauthor | Jay Chol Choi | - |
dc.contributor.googleauthor | Joong-Goo Kim | - |
dc.contributor.googleauthor | Jee-Hyun Kwon | - |
dc.contributor.googleauthor | Wook-Joo Kim | - |
dc.contributor.googleauthor | Dong-Ick Shin | - |
dc.contributor.googleauthor | Kyu Sun Yum | - |
dc.contributor.googleauthor | Sung-Il Sohn | - |
dc.contributor.googleauthor | Jeong-Ho Hong | - |
dc.contributor.googleauthor | Chulho Kim | - |
dc.contributor.googleauthor | Sang-Hwa Lee | - |
dc.contributor.googleauthor | Juneyoung Lee | - |
dc.contributor.googleauthor | Mohammed A Almekhlafi | - |
dc.contributor.googleauthor | Andrew Demchuk | - |
dc.contributor.googleauthor | Hee-Joon Bae | - |
dc.identifier.doi | 10.3389/fneur.2022.955725 | - |
dc.contributor.localId | A02513 | - |
dc.relation.journalcode | J02996 | - |
dc.identifier.eissn | 1664-2295 | - |
dc.identifier.pmid | 35989920 | - |
dc.subject.keyword | CRCS-K | - |
dc.subject.keyword | early neurological deterioration | - |
dc.subject.keyword | endovascular recanalization | - |
dc.subject.keyword | low NIHSS score | - |
dc.subject.keyword | mild stroke | - |
dc.subject.keyword | multicenter registry | - |
dc.contributor.alternativeName | Yoo, Joon Sang | - |
dc.contributor.affiliatedAuthor | 유준상 | - |
dc.citation.volume | 13 | - |
dc.citation.startPage | 955725 | - |
dc.identifier.bibliographicCitation | FRONTIERS IN NEUROLOGY, Vol.13 : 955725, 2022-08 | - |
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