Cited 0 times in
Hemodynamic responses to 1 MAC desflurane inhalation during anesthesia induction with propofol bolus and remifentanil continuous infusion: a prospective randomized single-blind clinical investigation
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김지영 | - |
dc.date.accessioned | 2023-03-27T02:40:08Z | - |
dc.date.available | 2023-03-27T02:40:08Z | - |
dc.date.issued | 2023-02 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/193666 | - |
dc.description.abstract | Background: Desflurane is not recommended during anesthesia induction because of its sympathetic stimulation effect, particularly in patients with myocardial ischemic disease. To date, the hemodynamic response to 1 MAC desflurane inhalation in combination with remifentanil infusion during anesthesia induction has rarely been reported. Methods: This investigation was designed to compare hemodynamic responses to 1 MAC desflurane (group D, n = 200) with sevoflurane (group S, n = 200) during anesthesia induction and endotracheal intubation in adult patients undergoing elective spine surgery. Subgroup analysis of the different age subgroups was also performed. With continuous infusion of remifentanil 0.1 μg/kg/min, anesthesia was induced with propofol bolus, and endotracheal intubation was performed after muscle relaxation. Heart rate (HR) and mean arterial blood pressure (MAP) were measured every minute for 5 min after anesthesia induction (T1-5) and after endotracheal intubation (T6-10). Results: HR was significantly higher in group D (n = 182) than in group S (n = 173) at T3-10 except at T6 (1 min after intubation) (all P < 0.05). In the age-based subgroup analyses, which subdivided the group D and S into four subgroups based on patient's age, the changes in HR from baseline values were significantly different between the coeval subgroups of patients in their 20-29 years and 30-39 years of age (all P < 0.05). MAP was reduced from baseline value, irrespective of group and age. Conclusion: Inhalation of 1 MAC desflurane during anesthesia induction with propofol bolus and remifentanil continuous infusion and during endotracheal intubation was more likely to induce elevations in HR more likely than 1 MAC sevoflurane, especially in younger patients. Trial registration: This study was registered in the Clinical Research Information Service (CRIS, http://cris.nih.go.kr ) of the Republic of Korea on Feb 12, 2016 (Registration No. KCT 0,001,813). | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | BioMed Central | - |
dc.relation.isPartOf | BMC ANESTHESIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Anesthesia, General | - |
dc.subject.MESH | Anesthetics, Inhalation* / pharmacology | - |
dc.subject.MESH | Anesthetics, Intravenous / pharmacology | - |
dc.subject.MESH | Desflurane / pharmacology | - |
dc.subject.MESH | Heart Rate | - |
dc.subject.MESH | Hemodynamics | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Isoflurane* / pharmacology | - |
dc.subject.MESH | Piperidines / adverse effects | - |
dc.subject.MESH | Propofol* / pharmacology | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Remifentanil / pharmacology | - |
dc.subject.MESH | Sevoflurane / pharmacology | - |
dc.subject.MESH | Single-Blind Method | - |
dc.subject.MESH | Young Adult | - |
dc.title | Hemodynamic responses to 1 MAC desflurane inhalation during anesthesia induction with propofol bolus and remifentanil continuous infusion: a prospective randomized single-blind clinical investigation | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) | - |
dc.contributor.googleauthor | Jong Wha Lee | - |
dc.contributor.googleauthor | Mi Kyeong Kim | - |
dc.contributor.googleauthor | Ji Young Kim | - |
dc.identifier.doi | 10.1186/s12871-023-02002-6 | - |
dc.contributor.localId | A00977 | - |
dc.relation.journalcode | J00349 | - |
dc.identifier.eissn | 1471-2253 | - |
dc.identifier.pmid | 36814199 | - |
dc.subject.keyword | Age | - |
dc.subject.keyword | Desflurane | - |
dc.subject.keyword | Hemodynamic response | - |
dc.subject.keyword | Remifentanil | - |
dc.subject.keyword | Sevoflurane | - |
dc.contributor.alternativeName | Kim, Ji Young | - |
dc.contributor.affiliatedAuthor | 김지영 | - |
dc.citation.volume | 23 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 59 | - |
dc.identifier.bibliographicCitation | BMC ANESTHESIOLOGY, Vol.23(1) : 59, 2023-02 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.