Cited 11 times in
Emergence of NDM-1-producing Pseudomonas aeruginosa Sequence Type 773 Clone: Shift of Carbapenemase Molecular Epidemiology and Spread of 16S rRNA Methylase Genes in Korea
DC Field | Value | Language |
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dc.contributor.author | 정석훈 | - |
dc.contributor.author | 최유정 | - |
dc.date.accessioned | 2023-03-22T02:02:11Z | - |
dc.date.available | 2023-03-22T02:02:11Z | - |
dc.date.issued | 2023-03 | - |
dc.identifier.issn | 2234-3806 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/193505 | - |
dc.description.abstract | Imipenemase (IMP)-6-producing Pseudomonas aeruginosa sequence type (ST) 235 is a dominant clone of carbapenemase-producing P. aeruginosa (CPPAE) in Korea. As part of the Antimicrobial Resistance Surveillance System in Korea, we found an increase in the carbapenem resistance rate of P. aeruginosa isolates from blood cultures and a shift in the molecular epidemiology of CPPAE. A total of 212 non-duplicated P. aeruginosa blood isolates were obtained from nine general hospitals and two nursing homes. Twenty-four isolates were identified as CPPAE. We observed the emergence of the NDM-1 P. aeruginosa ST 773 clone (N=10), mostly from Gyeongsang Province. The IMP-6 ST 235 clone (N=11) was detected in all provinces. CPPAE isolates showed very high resistance rates to amikacin, and all NDM-1 P. aeruginosa strains carried rmtB. This is the first nationwide surveillance of the recently emerged NDM-1-producing P. aeruginosa ST773 clone in Korea. Continuous surveillance is necessary to prevent the infection and transmission of carbapenem- and amikacin-resistant P. aeruginosa in Korea. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Korean Society for Laboratory Medicine | - |
dc.relation.isPartOf | ANNALS OF LABORATORY MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Amikacin / pharmacology | - |
dc.subject.MESH | Anti-Bacterial Agents / pharmacology | - |
dc.subject.MESH | Anti-Infective Agents* | - |
dc.subject.MESH | Bacterial Proteins / genetics | - |
dc.subject.MESH | Carbapenems / pharmacology | - |
dc.subject.MESH | Clone Cells | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Microbial Sensitivity Tests | - |
dc.subject.MESH | Molecular Epidemiology | - |
dc.subject.MESH | Pseudomonas Infections* / diagnosis | - |
dc.subject.MESH | Pseudomonas Infections* / epidemiology | - |
dc.subject.MESH | Pseudomonas aeruginosa / genetics | - |
dc.subject.MESH | RNA, Ribosomal, 16S / genetics | - |
dc.subject.MESH | beta-Lactamases / genetics | - |
dc.title | Emergence of NDM-1-producing Pseudomonas aeruginosa Sequence Type 773 Clone: Shift of Carbapenemase Molecular Epidemiology and Spread of 16S rRNA Methylase Genes in Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학교실) | - |
dc.contributor.googleauthor | Yu Jeong Choi | - |
dc.contributor.googleauthor | Young Ah Kim | - |
dc.contributor.googleauthor | Kim Junglim | - |
dc.contributor.googleauthor | Seok Hoon Jeong | - |
dc.contributor.googleauthor | Jong Hee Shin | - |
dc.contributor.googleauthor | Kyeong Seob Shin | - |
dc.contributor.googleauthor | Jeong Hwan Shin | - |
dc.contributor.googleauthor | Young Ree Kim | - |
dc.contributor.googleauthor | Hyun Soo Kim | - |
dc.contributor.googleauthor | Young Uh | - |
dc.contributor.googleauthor | Nam Hee Ryoo | - |
dc.identifier.doi | 10.3343/alm.2023.43.2.196 | - |
dc.contributor.localId | A03619 | - |
dc.relation.journalcode | J00164 | - |
dc.identifier.eissn | 2234-3814 | - |
dc.identifier.pmid | 36281514 | - |
dc.subject.keyword | 16S rRNA methylase gene | - |
dc.subject.keyword | Amikacin | - |
dc.subject.keyword | Molecular Epidemiology | - |
dc.subject.keyword | Pseudomonas aeruginosa | - |
dc.subject.keyword | Sequence type 773 | - |
dc.subject.keyword | β-lactamase NDM-1 | - |
dc.contributor.alternativeName | Jeong, Seok Hoon | - |
dc.contributor.affiliatedAuthor | 정석훈 | - |
dc.citation.volume | 43 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 196 | - |
dc.citation.endPage | 199 | - |
dc.identifier.bibliographicCitation | ANNALS OF LABORATORY MEDICINE, Vol.43(2) : 196-199, 2023-03 | - |
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