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Comparison of oncologic outcomes between open and laparoscopic distal pancreatectomy for pancreatic ductal adenocarcinoma using data from the KOTUS-BP national database: overcoming selection bias and the necessity of definite indications
DC Field | Value | Language |
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dc.contributor.author | 강창무 | - |
dc.contributor.author | 박준성 | - |
dc.contributor.author | 황호경 | - |
dc.date.accessioned | 2023-03-21T07:25:02Z | - |
dc.date.available | 2023-03-21T07:25:02Z | - |
dc.date.issued | 2022-10 | - |
dc.identifier.issn | 1365-182X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/193361 | - |
dc.description.abstract | Background: Despite the lack of high-level evidence, laparoscopic distal pancreatectomy (LDP) is frequently performed in patients with pancreatic ductal adenocarcinoma (PDAC) owing to advancements in surgical techniques. The aim of this study was to investigate the long-term oncologic outcomes of LDP in patients with PDAC via propensity score matching (PSM) analysis using data from a large-scale national database. Methods: A total of 1202 patients who were treated for PDAC via distal pancreatectomy across 16 hospitals were included in the Korean Tumor Registry System-Biliary Pancreas. The 5-year overall (5YOSR) and disease-free (5YDFSR) survival rates were compared between LDP and open DP (ODP). Results: ODP and LDP were performed in 846 and 356 patients, respectively. The ODP group included more aggressive surgeries with higher pathologic stage, R0 resection rate, and number of retrieved lymph nodes. After PSM, the 5YOSRs for ODP and LDP were 37.3% and 41.4% (p = 0.150), while the 5YDFSRs were 23.4% and 27.2% (p = 0.332), respectively. Prognostic factors for 5YOSR included R status, T stage, N stage, differentiation, and lymphovascular invasion. Conclusion: LDP was performed in a selected group of patients with PDAC. Within this group, long-term oncologic outcomes were comparable to those observed following ODP. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | HPB | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Carcinoma, Pancreatic Ductal* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Laparoscopy* / adverse effects | - |
dc.subject.MESH | Laparoscopy* / methods | - |
dc.subject.MESH | Pancreatectomy / adverse effects | - |
dc.subject.MESH | Pancreatectomy / methods | - |
dc.subject.MESH | Pancreatic Neoplasms* / pathology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Selection Bias | - |
dc.title | Comparison of oncologic outcomes between open and laparoscopic distal pancreatectomy for pancreatic ductal adenocarcinoma using data from the KOTUS-BP national database: overcoming selection bias and the necessity of definite indications | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.googleauthor | Hongbeom Kim | - |
dc.contributor.googleauthor | Jin Seok Heo | - |
dc.contributor.googleauthor | Chang Moo Kang | - |
dc.contributor.googleauthor | Ho Kyoung Hwang | - |
dc.contributor.googleauthor | Ho-Seong Han | - |
dc.contributor.googleauthor | Yoo-Seok Yoon | - |
dc.contributor.googleauthor | Joon Seong Park | - |
dc.contributor.googleauthor | Sung-Sik Han | - |
dc.contributor.googleauthor | Yong Hoon Kim | - |
dc.contributor.googleauthor | Hyeon Kook Lee | - |
dc.contributor.googleauthor | Young-Dong Yu | - |
dc.contributor.googleauthor | In Seok Choi | - |
dc.contributor.googleauthor | Jae Do Yang | - |
dc.contributor.googleauthor | Younghoon Roh | - |
dc.contributor.googleauthor | Seong-Ryong Kim | - |
dc.contributor.googleauthor | Junchul Chung | - |
dc.contributor.googleauthor | Sang Hwa Song | - |
dc.contributor.googleauthor | Song Cheol Kim | - |
dc.contributor.googleauthor | Jin-Young Jang | - |
dc.identifier.doi | 10.1016/j.hpb.2022.01.012 | - |
dc.contributor.localId | A00088 | - |
dc.contributor.localId | A01672 | - |
dc.contributor.localId | A04497 | - |
dc.relation.journalcode | J03345 | - |
dc.identifier.eissn | 1477-2574 | - |
dc.identifier.pmid | 35871134 | - |
dc.identifier.url | https://www.clinicalkey.com/#!/content/playContent/1-s2.0-S1365182X22000466 | - |
dc.contributor.alternativeName | Kang, Chang Moo | - |
dc.contributor.affiliatedAuthor | 강창무 | - |
dc.contributor.affiliatedAuthor | 박준성 | - |
dc.contributor.affiliatedAuthor | 황호경 | - |
dc.citation.volume | 24 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1804 | - |
dc.citation.endPage | 1812 | - |
dc.identifier.bibliographicCitation | HPB, Vol.24(10) : 1804-1812, 2022-10 | - |
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