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Three months-longitudinal changes in relative telomere length, blood chemistries, and self-report questionnaires in meditation practitioners compared to novice individuals during midlife
DC Field | Value | Language |
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dc.contributor.author | 김지영 | - |
dc.date.accessioned | 2023-03-21T07:24:31Z | - |
dc.date.available | 2023-03-21T07:24:31Z | - |
dc.date.issued | 2022-10 | - |
dc.identifier.issn | 0025-7974 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/193353 | - |
dc.description.abstract | Aging accelerates during midlife. Researches have shown the health benefits of mind-body intervention (MBI). However, whether MBI is involved with aging process has not been well understood. In this study, we approach to examine the relations of MBI with this process by investigating an aging marker of the peripheral blood, blood chemistry, and self-report questionnaires. A quasi-experimental design was applied. Experienced MBI practitioners participated in a 3-month intensive meditation training, while the age, gender-matched MBI-naïve controls led a normal daily life. Measurements were taken at before and after the 3 months for relative telomere length (RTL), blood chemistry, and self-report questionnaires including items about sleep quality, somatic symptoms, depression, anxiety, stress, emotional intelligence (EI), and self-regulation. For RTL, the repeated measures analysis of variance showed a significant group*time interaction (P = .013) with a significant post hoc result (P = .030) within the control group: RTL was significantly reduced in the control while it was maintained in the meditation group. In repeated measures analysis of variance for blood chemistries, there were significant group differences between the groups in glucose and total protein. In the post hoc comparison analysis, at post measurements, the meditation group exhibited significantly lower values than the control group in both glucose and total protein. There were significant group-wise differences in the correlations of RTL with triglyceride (TG), high-density lipoprotein (HDL), glutamic oxaloacetic transaminase and glutamic pyruvic transaminase. Any of self-report results did not show significant changes in group*time interaction. However, there were group differences with significant (P < .05) or a tendency (.05 < P < .1) level. There were significant improvements in depression, stress and EI as well as tendencies of improvement in sleep quality and anxiety, in the meditation group compared to the control group. Our results suggest that meditation practice may have a potential to modify aging process in molecular cellular level combined with changes in psychological dimension. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Lippincott Williams & Wilkins | - |
dc.relation.isPartOf | MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Alanine Transaminase | - |
dc.subject.MESH | Aspartate Aminotransferases | - |
dc.subject.MESH | Glucose | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Lipoproteins, HDL | - |
dc.subject.MESH | Meditation* / methods | - |
dc.subject.MESH | Self Report | - |
dc.subject.MESH | Surveys and Questionnaires | - |
dc.subject.MESH | Telomere | - |
dc.subject.MESH | Triglycerides | - |
dc.title | Three months-longitudinal changes in relative telomere length, blood chemistries, and self-report questionnaires in meditation practitioners compared to novice individuals during midlife | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) | - |
dc.contributor.googleauthor | Min-Kyu Sung | - |
dc.contributor.googleauthor | Eugene Koh | - |
dc.contributor.googleauthor | Yunjeong Kang | - |
dc.contributor.googleauthor | Jin-Hee Lee | - |
dc.contributor.googleauthor | Ji-Yeon Park | - |
dc.contributor.googleauthor | Ji Young Kim | - |
dc.contributor.googleauthor | So-Young Shin | - |
dc.contributor.googleauthor | Yeon-Hee Kim | - |
dc.contributor.googleauthor | Noriko Setou | - |
dc.contributor.googleauthor | Ul Soon Lee | - |
dc.contributor.googleauthor | Hyun-Jeong Yang | - |
dc.identifier.doi | 10.1097/MD.0000000000030930 | - |
dc.contributor.localId | A00977 | - |
dc.relation.journalcode | J02214 | - |
dc.identifier.eissn | 1536-5964 | - |
dc.identifier.pmid | 36254044 | - |
dc.contributor.alternativeName | Kim, Ji Young | - |
dc.contributor.affiliatedAuthor | 김지영 | - |
dc.citation.volume | 101 | - |
dc.citation.number | 41 | - |
dc.citation.startPage | e30930 | - |
dc.identifier.bibliographicCitation | MEDICINE, Vol.101(41) : e30930, 2022-10 | - |
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