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Comparison of Three Cardiovascular Risk Scores among HIV-Infected Patients in Korea: The Korea HIV/AIDS Cohort Study
DC Field | Value | Language |
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dc.contributor.author | 최준용 | - |
dc.date.accessioned | 2023-03-10T01:29:27Z | - |
dc.date.available | 2023-03-10T01:29:27Z | - |
dc.date.issued | 2022-09 | - |
dc.identifier.issn | 2093-2340 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/193188 | - |
dc.description.abstract | Background: We investigated cardiovascular disease (CVD), risk factors for CVD, and applicability of the three known CVD risk equations in the Korean human immunodeficiency virus/ Acquired Immune Deficiency Syndrome (HIV/AIDS) cohort. Materials and methods: The study parcitipants were HIV-infected patients in a Korean HIV/AIDS cohort enrolled from 19 hospitals between 2006 and 2017. Data collected at entry to the cohort were analyzed. The 5-year CVD risk in each participant was calculated using three CVD risk equations: reduced CVD prediction model of HIV-specific data collection on adverse effects of anti-HIV drugs (R-DAD), Framingham general CVD risk score (FRS), and Korean Coronary Heart Disease Risk Score (KRS). Results: CVD events were observed in 11 of 586 HIV-infected patients during a 5-year (median) follow-up period. The incidence of CVD was 4.11 per 1,000 person-years. Older age (64 vs. 41 years, P = 0.005) and diabetes mellitus (45.5% vs. 6.4%, P <0.001) were more frequent in patients with CVD. Using R-DAD, FRS, and KRS, 1.9%, 2.4%, and 0.7% of patients, respectively, were considered to have a very high risk (≥10%) of 5-year CVD. The discriminatory capacities of the three prediction models were good, with c-statistic values of 0.829 (P <0.001) for R-DAD, 0.824 (P <0.001) for FRS, and 0.850 (P = 0.001) for KRS. Conclusion: The FRS, R-DAD, and KRS performed well in the Korean HIV/AIDS cohort. A larger cohort and a longer period of follow-up may be necessary to demonstrate the risk factors and develop an independent CVD risk prediction model specific to Korean patients with HIV. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean, English | - |
dc.publisher | 대한감염학회 | - |
dc.relation.isPartOf | INFECTION AND CHEMOTHERAPY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Comparison of Three Cardiovascular Risk Scores among HIV-Infected Patients in Korea: The Korea HIV/AIDS Cohort Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Ji Yun Bae | - |
dc.contributor.googleauthor | Soo Min Kim | - |
dc.contributor.googleauthor | Yunsu Choi | - |
dc.contributor.googleauthor | Jun Yong Choi | - |
dc.contributor.googleauthor | Sang Il Kim | - |
dc.contributor.googleauthor | Shin-Woo Kim | - |
dc.contributor.googleauthor | Bo Young Park | - |
dc.contributor.googleauthor | Bo Youl Choi | - |
dc.contributor.googleauthor | Hee Jung Choi | - |
dc.identifier.doi | 10.3947/ic.2022.0048 | - |
dc.contributor.localId | A04191 | - |
dc.relation.journalcode | J01053 | - |
dc.identifier.eissn | 2092-6448 | - |
dc.identifier.pmid | 35920266 | - |
dc.subject.keyword | Cardiovascular diseases | - |
dc.subject.keyword | Coronary disease | - |
dc.subject.keyword | HIV | - |
dc.subject.keyword | Korea | - |
dc.contributor.alternativeName | Choi, Jun Yong | - |
dc.contributor.affiliatedAuthor | 최준용 | - |
dc.citation.volume | 54 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 409 | - |
dc.citation.endPage | 418 | - |
dc.identifier.bibliographicCitation | INFECTION AND CHEMOTHERAPY, Vol.54(3) : 409-418, 2022-09 | - |
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