76 415

Cited 1 times in

Silodosin versus Tamsulosin for Medical Expulsive Therapy of Ureteral Stones: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials

DC Field Value Language
dc.contributor.author문영준-
dc.contributor.author이주용-
dc.contributor.author정재용-
dc.contributor.author조강수-
dc.date.accessioned2023-03-03T02:33:49Z-
dc.date.available2023-03-03T02:33:49Z-
dc.date.issued2022-12-
dc.identifier.issn1010-660X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/192850-
dc.description.abstractBackground and Objectives: This systematic review and meta-analysis of randomized controlled trials was performed to compare the therapeutic effects and safety profiles of silodosin and tamsulosin for medical expulsive therapy (MET) of ureteral stones. Materials and Methods: We searched PubMed, EMBASE, the Cochrane Library, and Web of Science to identify articles published before July 2022 that described randomized controlled trials comparing silodosin and tamsulosin for MET of ureteral stones. Endpoints were stone expulsion rate, stone expulsion time, and total complication rate. Results: In total, 14 studies were included in our analysis. The size of ureteral stones was <1 cm. Compared with tamsulosin, silodosin resulted in a significantly higher stone expulsion rate (p < 0.01, odds ratio (OR) = 2.42, 95% confidence interval (CI) = 1.91 to 3.06, I2 = 0%) and significantly shorter stone expulsion time (p < 0.01, mean difference = -3.04, 95% CI = -4.46 to -1.63, I2 = 89%). The total complication rate did not significantly differ between silodosin and tamsulosin (p = 0.33, OR = 1.15, 95% CI = 0.87 to 1.52, I2 = 7%). Conclusions: Compared with tamsulosin, silodosin resulted in significantly better expulsion of ureteral stones <1 cm. The total complication rate did not significantly differ between silodosin and tamsulosin. Thus, silodosin may be superior to tamsulosin for MET of ureter stones <1 cm.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherMDPI-
dc.relation.isPartOfMEDICINA-LITHUANIA-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAdrenergic alpha-1 Receptor Antagonists / therapeutic use-
dc.subject.MESHHumans-
dc.subject.MESHRandomized Controlled Trials as Topic-
dc.subject.MESHTamsulosin / therapeutic use-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHUreteral Calculi* / drug therapy-
dc.titleSilodosin versus Tamsulosin for Medical Expulsive Therapy of Ureteral Stones: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Urology (비뇨의학교실)-
dc.contributor.googleauthorHae Do Jung-
dc.contributor.googleauthorKang Su Cho-
dc.contributor.googleauthorDae Young Jun-
dc.contributor.googleauthorJae Yong Jeong-
dc.contributor.googleauthorYoung Joon Moon-
dc.contributor.googleauthorDoo Yong Chung-
dc.contributor.googleauthorDong Hyuk Kang-
dc.contributor.googleauthorSeok Cho-
dc.contributor.googleauthorJoo Yong Lee-
dc.identifier.doi10.3390/medicina58121794-
dc.contributor.localIdA06283-
dc.contributor.localIdA03161-
dc.contributor.localIdA06345-
dc.contributor.localIdA03801-
dc.relation.journalcodeJ03886-
dc.identifier.eissn1648-9144-
dc.identifier.pmid36556996-
dc.subject.keywordadrenergic alpha-1 receptor antagonists-
dc.subject.keywordmeta-analysis-
dc.subject.keywordsystematic review-
dc.subject.keywordureteral calculi-
dc.contributor.alternativeNameMoon, Young Joon-
dc.contributor.affiliatedAuthor문영준-
dc.contributor.affiliatedAuthor이주용-
dc.contributor.affiliatedAuthor정재용-
dc.contributor.affiliatedAuthor조강수-
dc.citation.volume58-
dc.citation.number12-
dc.citation.startPage1794-
dc.identifier.bibliographicCitationMEDICINA-LITHUANIA, Vol.58(12) : 1794, 2022-12-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.