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Silodosin versus Tamsulosin for Medical Expulsive Therapy of Ureteral Stones: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials
DC Field | Value | Language |
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dc.contributor.author | 문영준 | - |
dc.contributor.author | 이주용 | - |
dc.contributor.author | 정재용 | - |
dc.contributor.author | 조강수 | - |
dc.date.accessioned | 2023-03-03T02:33:49Z | - |
dc.date.available | 2023-03-03T02:33:49Z | - |
dc.date.issued | 2022-12 | - |
dc.identifier.issn | 1010-660X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/192850 | - |
dc.description.abstract | Background and Objectives: This systematic review and meta-analysis of randomized controlled trials was performed to compare the therapeutic effects and safety profiles of silodosin and tamsulosin for medical expulsive therapy (MET) of ureteral stones. Materials and Methods: We searched PubMed, EMBASE, the Cochrane Library, and Web of Science to identify articles published before July 2022 that described randomized controlled trials comparing silodosin and tamsulosin for MET of ureteral stones. Endpoints were stone expulsion rate, stone expulsion time, and total complication rate. Results: In total, 14 studies were included in our analysis. The size of ureteral stones was <1 cm. Compared with tamsulosin, silodosin resulted in a significantly higher stone expulsion rate (p < 0.01, odds ratio (OR) = 2.42, 95% confidence interval (CI) = 1.91 to 3.06, I2 = 0%) and significantly shorter stone expulsion time (p < 0.01, mean difference = -3.04, 95% CI = -4.46 to -1.63, I2 = 89%). The total complication rate did not significantly differ between silodosin and tamsulosin (p = 0.33, OR = 1.15, 95% CI = 0.87 to 1.52, I2 = 7%). Conclusions: Compared with tamsulosin, silodosin resulted in significantly better expulsion of ureteral stones <1 cm. The total complication rate did not significantly differ between silodosin and tamsulosin. Thus, silodosin may be superior to tamsulosin for MET of ureter stones <1 cm. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | MEDICINA-LITHUANIA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adrenergic alpha-1 Receptor Antagonists / therapeutic use | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Randomized Controlled Trials as Topic | - |
dc.subject.MESH | Tamsulosin / therapeutic use | - |
dc.subject.MESH | Treatment Outcome | - |
dc.subject.MESH | Ureteral Calculi* / drug therapy | - |
dc.title | Silodosin versus Tamsulosin for Medical Expulsive Therapy of Ureteral Stones: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Urology (비뇨의학교실) | - |
dc.contributor.googleauthor | Hae Do Jung | - |
dc.contributor.googleauthor | Kang Su Cho | - |
dc.contributor.googleauthor | Dae Young Jun | - |
dc.contributor.googleauthor | Jae Yong Jeong | - |
dc.contributor.googleauthor | Young Joon Moon | - |
dc.contributor.googleauthor | Doo Yong Chung | - |
dc.contributor.googleauthor | Dong Hyuk Kang | - |
dc.contributor.googleauthor | Seok Cho | - |
dc.contributor.googleauthor | Joo Yong Lee | - |
dc.identifier.doi | 10.3390/medicina58121794 | - |
dc.contributor.localId | A06283 | - |
dc.contributor.localId | A03161 | - |
dc.contributor.localId | A06345 | - |
dc.contributor.localId | A03801 | - |
dc.relation.journalcode | J03886 | - |
dc.identifier.eissn | 1648-9144 | - |
dc.identifier.pmid | 36556996 | - |
dc.subject.keyword | adrenergic alpha-1 receptor antagonists | - |
dc.subject.keyword | meta-analysis | - |
dc.subject.keyword | systematic review | - |
dc.subject.keyword | ureteral calculi | - |
dc.contributor.alternativeName | Moon, Young Joon | - |
dc.contributor.affiliatedAuthor | 문영준 | - |
dc.contributor.affiliatedAuthor | 이주용 | - |
dc.contributor.affiliatedAuthor | 정재용 | - |
dc.contributor.affiliatedAuthor | 조강수 | - |
dc.citation.volume | 58 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1794 | - |
dc.identifier.bibliographicCitation | MEDICINA-LITHUANIA, Vol.58(12) : 1794, 2022-12 | - |
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