The collaborative outcomes study on health and functioning during infection times in adults (COH-FIT-Adults): Design and methods of an international online survey targeting physical and mental health effects of the COVID-19 pandemic

Marco Solmi; Andrés Estradé; Trevor Thompson; Agorastos Agorastos; Joaquim Radua; Samuele Cortese; Elena Dragioti; Friedrich Leisch; Davy Vancampfort; Lau Caspar Thygesen; Harald Aschauer; Monika Schloegelhofer; Elena Akimova; Andres Schneeberger; Christian G Huber; Gregor Hasler; Philippe Conus; Kim Q Do Cuénod; Roland von Känel; Gonzalo Arrondo; Paolo Fusar-Poli; Philip Gorwood; Pierre-Michel Llorca; Marie-Odile Krebs; Elisabetta Scanferla; Taishiro Kishimoto; Golam Rabbani; Karolina Skonieczna-Żydecka; Paolo Brambilla; Angela Favaro; Akihiro Takamiya; Leonardo Zoccante; Marco Colizzi; Julie Bourgin; Karol Kamiński; Maryam Moghadasin; Soraya Seedat; Evan Matthews; John Wells; Emilia Vassilopoulou; Ary Gadelha; Kuan-Pin Su; Jun Soo Kwon; Minah Kim; Tae Young Lee; Oleg Papsuev; Denisa Manková; Andrea Boscutti; Cristiano Gerunda; Diego Saccon; Elena Righi; Francesco Monaco; Giovanni Croatto; Guido Cereda; Jacopo Demurtas; Natascia Brondino; Nicola Veronese; Paolo Enrico; Pierluigi Politi; Valentina Ciappolino; Andrea Pfennig; Andreas Bechdolf; Andreas Meyer-Lindenberg; Kai G Kahl; Katharina Domschke; Michael Bauer; Nikolaos Koutsouleris; Sibylle Winter; Stefan Borgwardt; Istvan Bitter; Judit Balazs; Pal Czobor; Zsolt Unoka; Dimitris Mavridis; Konstantinos Tsamakis; Vasilios P Bozikas; Chavit Tunvirachaisakul; Michael Maes; Teerayuth Rungnirundorn; Thitiporn Supasitthumrong; Ariful Haque; Andre R Brunoni; Carlos Gustavo Costardi; Felipe Barreto Schuch; Guilherme Polanczyk; Jhoanne Merlyn Luiz; Lais Fonseca; Luana V Aparicio; Samira S Valvassori; Merete Nordentoft; Per Vendsborg; Sofie Have Hoffmann; Jihed Sehli; Norman Sartorius; Sabina Heuss; Daniel Guinart; Jane Hamilton; John Kane; Jose Rubio; Michael Sand; Ai Koyanagi; Aleix Solanes; Alvaro Andreu-Bernabeu; Antonia San José Cáceres; Celso Arango; Covadonga M Díaz-Caneja; Diego Hidalgo-Mazzei; Eduard Vieta; Javier Gonzalez-Peñas; Lydia Fortea; Mara Parellada; Miquel A Fullana; Norma Verdolini; Eva Fárková; Karolina Janků; Mark Millan; Mihaela Honciuc; Anna Moniuszko-Malinowska; Igor Łoniewski; Jerzy Samochowiec; Łukasz Kiszkiel; Maria Marlicz; Paweł Sowa; Wojciech Marlicz; Georgina Spies; Brendon Stubbs; Joseph Firth; Sarah Sullivan; Asli Enez Darcin; Hatice Aksu; Nesrin Dilbaz; Onur Noyan; Momoko Kitazawa; Shunya Kurokawa; Yuki Tazawa; Alejandro Anselmi; Cecilia Cracco; Ana Inés Machado; Natalia Estrade; Diego De Leo; Jackie Curtis; Michael Berk; Philip Ward; Scott Teasdale; Simon Rosenbaum; Wolfgang Marx; Adrian Vasile Horodnic; Liviu Oprea; Ovidiu Alexinschi; Petru Ifteni; Serban Turliuc; Tudor Ciuhodaru; Alexandra Bolos; Valentin Matei; Dorien H Nieman; Iris Sommer; Jim van Os; Therese van Amelsvoort; Ching-Fang Sun; Ta-Wei Guu; Can Jiao; Jieting Zhang; Jialin Fan; Liye Zou; Xin Yu; Xinli Chi; Philippe de Timary; Ruud van Winke; Bernardo Ng; Edilberto Pena; Ramon Arellano; Raquel Roman; Thelma Sanchez; Larisa Movina; Pedro Morgado; Sofia Brissos; Oleg Aizberg; Anna Mosina; Damir Krinitski; James Mugisha; Dena Sadeghi-Bahmani; Masoud Sadeghi; Samira Hadi; Serge Brand; Antonia Errazuriz; Nicolas Crossley; Dragana Ignjatovic Ristic; Carlos López-Jaramillo; Dimitris Efthymiou; Praveenlal Kuttichira; Roy Abraham Kallivayalil; Afzal Javed; Muhammad Iqbal Afridi; Bawo James; Omonefe Joy Seb-Akahomen; Jess Fiedorowicz; Andre F Carvalho; Jeff Daskalakis; Lakshmi N Yatham; Lin Yang; Tarek Okasha; Aïcha Dahdouh; Björn Gerdle; Jari Tiihonen; Jae Il Shin; Jinhee Lee; Ahmed Mhalla; Lotfi Gaha; Takoua Brahim; Kuanysh Altynbekov; Nikolay Negay; Saltanat Nurmagambetova; Yasser Abu Jamei; Mark Weiser; Christoph U Correll

doi:10.1016/j.jad.2021.07.048

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The collaborative outcomes study on health and functioning during infection times in adults (COH-FIT-Adults): Design and methods of an international online survey targeting physical and mental health effects of the COVID-19 pandemic

Authors: Marco Solmi ; Andrés Estradé ; Trevor Thompson ; Agorastos Agorastos ; Joaquim Radua ; Samuele Cortese ; Elena Dragioti ; Friedrich Leisch ; Davy Vancampfort ; Lau Caspar Thygesen ; Harald Aschauer ; Monika Schloegelhofer ; Elena Akimova ; Andres Schneeberger ; Christian G Huber ; Gregor Hasler ; Philippe Conus ; Kim Q Do Cuénod ; Roland von Känel ; Gonzalo Arrondo ; Paolo Fusar-Poli ; Philip Gorwood ; Pierre-Michel Llorca ; Marie-Odile Krebs ; Elisabetta Scanferla ; Taishiro Kishimoto ; Golam Rabbani ; Karolina Skonieczna-Żydecka ; Paolo Brambilla ; Angela Favaro ; Akihiro Takamiya ; Leonardo Zoccante ; Marco Colizzi ; Julie Bourgin ; Karol Kamiński ; Maryam Moghadasin ; Soraya Seedat ; Evan Matthews ; John Wells ; Emilia Vassilopoulou ; Ary Gadelha ; Kuan-Pin Su ; Jun Soo Kwon ; Minah Kim ; Tae Young Lee ; Oleg Papsuev ; Denisa Manková ; Andrea Boscutti ; Cristiano Gerunda ; Diego Saccon ; Elena Righi ; Francesco Monaco ; Giovanni Croatto ; Guido Cereda ; Jacopo Demurtas ; Natascia Brondino ; Nicola Veronese ; Paolo Enrico ; Pierluigi Politi ; Valentina Ciappolino ; Andrea Pfennig ; Andreas Bechdolf ; Andreas Meyer-Lindenberg ; Kai G Kahl ; Katharina Domschke ; Michael Bauer ; Nikolaos Koutsouleris ; Sibylle Winter ; Stefan Borgwardt ; Istvan Bitter ; Judit Balazs ; Pal Czobor ; Zsolt Unoka ; Dimitris Mavridis ; Konstantinos Tsamakis ; Vasilios P Bozikas ; Chavit Tunvirachaisakul ; Michael Maes ; Teerayuth Rungnirundorn ; Thitiporn Supasitthumrong ; Ariful Haque ; Andre R Brunoni ; Carlos Gustavo Costardi ; Felipe Barreto Schuch ; Guilherme Polanczyk ; Jhoanne Merlyn Luiz ; Lais Fonseca ; Luana V Aparicio ; Samira S Valvassori ; Merete Nordentoft ; Per Vendsborg ; Sofie Have Hoffmann ; Jihed Sehli ; Norman Sartorius ; Sabina Heuss ; Daniel Guinart ; Jane Hamilton ; John Kane ; Jose Rubio ; Michael Sand ; Ai Koyanagi ; Aleix Solanes ; Alvaro Andreu-Bernabeu ; Antonia San José Cáceres ; Celso Arango ; Covadonga M Díaz-Caneja ; Diego Hidalgo-Mazzei ; Eduard Vieta ; Javier Gonzalez-Peñas ; Lydia Fortea ; Mara Parellada ; Miquel A Fullana ; Norma Verdolini ; Eva Fárková ; Karolina Janků ; Mark Millan ; Mihaela Honciuc ; Anna Moniuszko-Malinowska ; Igor Łoniewski ; Jerzy Samochowiec ; Łukasz Kiszkiel ; Maria Marlicz ; Paweł Sowa ; Wojciech Marlicz ; Georgina Spies ; Brendon Stubbs ; Joseph Firth ; Sarah Sullivan ; Asli Enez Darcin ; Hatice Aksu ; Nesrin Dilbaz ; Onur Noyan ; Momoko Kitazawa ; Shunya Kurokawa ; Yuki Tazawa ; Alejandro Anselmi ; Cecilia Cracco ; Ana Inés Machado ; Natalia Estrade ; Diego De Leo ; Jackie Curtis ; Michael Berk ; Philip Ward ; Scott Teasdale ; Simon Rosenbaum ; Wolfgang Marx ; Adrian Vasile Horodnic ; Liviu Oprea ; Ovidiu Alexinschi ; Petru Ifteni ; Serban Turliuc ; Tudor Ciuhodaru ; Alexandra Bolos ; Valentin Matei ; Dorien H Nieman ; Iris Sommer ; Jim van Os ; Therese van Amelsvoort ; Ching-Fang Sun ; Ta-Wei Guu ; Can Jiao ; Jieting Zhang ; Jialin Fan ; Liye Zou ; Xin Yu ; Xinli Chi ; Philippe de Timary ; Ruud van Winke ; Bernardo Ng ; Edilberto Pena ; Ramon Arellano ; Raquel Roman ; Thelma Sanchez ; Larisa Movina ; Pedro Morgado ; Sofia Brissos ; Oleg Aizberg ; Anna Mosina ; Damir Krinitski ; James Mugisha ; Dena Sadeghi-Bahmani ; Masoud Sadeghi ; Samira Hadi ; Serge Brand ; Antonia Errazuriz ; Nicolas Crossley ; Dragana Ignjatovic Ristic ; Carlos López-Jaramillo ; Dimitris Efthymiou ; Praveenlal Kuttichira ; Roy Abraham Kallivayalil ; Afzal Javed ; Muhammad Iqbal Afridi ; Bawo James ; Omonefe Joy Seb-Akahomen ; Jess Fiedorowicz ; Andre F Carvalho ; Jeff Daskalakis ; Lakshmi N Yatham ; Lin Yang ; Tarek Okasha ; Aïcha Dahdouh ; Björn Gerdle ; Jari Tiihonen ; Jae Il Shin ; Jinhee Lee ; Ahmed Mhalla ; Lotfi Gaha ; Takoua Brahim ; Kuanysh Altynbekov ; Nikolay Negay ; Saltanat Nurmagambetova ; Yasser Abu Jamei ; Mark Weiser ; Christoph U Correll

Citation: JOURNAL OF AFFECTIVE DISORDERS, Vol.299 : 393-407, 2022-02

Journal Title: JOURNAL OF AFFECTIVE DISORDERS

ISSN: 0165-0327

Issue Date: 2022-02

MeSH: Adolescent ; Adult ; Anxiety ; COVID-19* ; Child ; Cross-Sectional Studies ; Depression ; Humans ; Mental Health ; Outcome Assessment, Health Care ; Pandemics* ; SARS-CoV-2

Keywords: COH-FIT ; COVID-19 ; adolescents ; adults ; anxiety ; children ; depression ; functioning ; international ; mental health ; physical health ; post-traumatic ; psychiatry ; representative ; resilience ; survey ; well-being

Abstract: Background: . High-quality comprehensive data on short-/long-term physical/mental health effects of the COVID-19 pandemic are needed.

Methods: . The Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT) is an international, multi-language (n=30) project involving >230 investigators from 49 countries/territories/regions, endorsed by national/international professional associations. COH-FIT is a multi-wave, on-line anonymous, cross-sectional survey [wave 1: 04/2020 until the end of the pandemic, 12 months waves 2/3 starting 6/24 months threreafter] for adults, adolescents (14-17), and children (6-13), utilizing non-probability/snowball and representative sampling. COH-FIT aims to identify non-modifiable/modifiable risk factors/treatment targets to inform prevention/intervention programs to improve social/health outcomes in the general population/vulnerable subgrous during/after COVID-19. In adults, co-primary outcomes are change from pre-COVID-19 to intra-COVID-19 in well-being (WHO-5) and a composite psychopathology P-Score. Key secondary outcomes are a P-extended score, global mental and physical health. Secondary outcomes include health-service utilization/functioning, treatment adherence, functioning, symptoms/behaviors/emotions, substance use, violence, among others.

Results: . Starting 04/26/2020, up to 14/07/2021 >151,000 people from 155 countries/territories/regions and six continents have participated. Representative samples of ≥1,000 adults have been collected in 15 countries. Overall, 43.0% had prior physical disorders, 16.3% had prior mental disorders, 26.5% were health care workers, 8.2% were aged ≥65 years, 19.3% were exposed to someone infected with COVID-19, 76.1% had been in quarantine, and 2.1% had been COVID 19-positive.

Limitations: . Cross-sectional survey, preponderance of non-representative participants.

Conclusions: . Results from COH-FIT will comprehensively quantify the impact of COVID-19, seeking to identify high-risk groups in need for acute and long-term intervention, and inform evidence-based health policies/strategies during this/future pandemics.