Cited 6 times in
Real-world clinical features, health-care utilization, and economic burden in decompensated cirrhosis patients: A national database
DC Field | Value | Language |
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dc.contributor.author | 김범경 | - |
dc.date.accessioned | 2023-03-03T02:09:25Z | - |
dc.date.available | 2023-03-03T02:09:25Z | - |
dc.date.issued | 2022-11 | - |
dc.identifier.issn | 0815-9319 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/192743 | - |
dc.description.abstract | Background: Patients with decompensated cirrhosis are well known to experience morbidity and mortality. Aim: We assessed clinical characteristics, health-care utilization, and economic burden according to the type, number, and combination of decompensation-related complications. Methods: We used recent nationally representative sample data from 2016 to 2018, covering approximately 13% of hospitalized patients in South Korea annually. Decompensation-related complications included ascites, hepatic encephalopathy (HE), gastroesophageal variceal (GEV) bleeding, and hepatorenal syndrome (HRS). Results: Among 14 601 patients with decompensated cirrhosis, 11 201 (76.7%) experienced ≥ 1 decompensation-related complications, and approximately three-quarters underwent hospitalization. The most prevalent decompensation-related complications were ascites (54.8%), GEV bleeding (33.2%), HE (27.4%), and HRS (3.6%). Patients with GEV bleeding exhibited the highest hospitalization rate (95.7%), and patients with HE or HRS underwent hospitalization for 4 weeks/year due to decompensated cirrhosis. Hospitalization costs were 1.9 times higher in patients with HRS than in those with ascites alone ($9022 vs $4673; P < 0.01). Once patients developed decompensation-related complications, 41.3% had ≥ 2 types of decompensation-related complications. As the number of decompensation-related complications increased from 0 to ≥ 3, health-care utilization and economic burden significantly increased in a stepwise manner; patients with ascites, GEV bleeding, and HE visited medical institutions 2.2 times more (11 vs 5/year; P < 0.01) and incurred 6.4 times greater medical expenditure ($11 060 vs $1728/year; P < 0.01) than those with ascites only. Conclusion: A substantial proportion of patients had multiple decompensation-related complications and socioeconomic burdens for decompensated cirrhosis considering admission rate, hospital stay, and costs increased markedly, depending on the number of decompensation-related complications. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Blackwell Scientific Publications | - |
dc.relation.isPartOf | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Ascites / epidemiology | - |
dc.subject.MESH | Ascites / etiology | - |
dc.subject.MESH | Ascites / therapy | - |
dc.subject.MESH | Financial Stress | - |
dc.subject.MESH | Hemorrhage | - |
dc.subject.MESH | Hepatic Encephalopathy* / epidemiology | - |
dc.subject.MESH | Hepatic Encephalopathy* / etiology | - |
dc.subject.MESH | Hepatic Encephalopathy* / therapy | - |
dc.subject.MESH | Hepatorenal Syndrome* / epidemiology | - |
dc.subject.MESH | Hepatorenal Syndrome* / etiology | - |
dc.subject.MESH | Hepatorenal Syndrome* / therapy | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Liver Cirrhosis / complications | - |
dc.subject.MESH | Liver Cirrhosis / epidemiology | - |
dc.subject.MESH | Liver Cirrhosis / therapy | - |
dc.subject.MESH | Patient Acceptance of Health Care | - |
dc.title | Real-world clinical features, health-care utilization, and economic burden in decompensated cirrhosis patients: A national database | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Hankil Lee | - |
dc.contributor.googleauthor | Beom Kyung Kim | - |
dc.identifier.doi | 10.1111/jgh.15962 | - |
dc.contributor.localId | A00487 | - |
dc.relation.journalcode | J01417 | - |
dc.identifier.eissn | 1440-1746 | - |
dc.identifier.pmid | 35862281 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1111/jgh.15962 | - |
dc.subject.keyword | South Korea | - |
dc.subject.keyword | cost | - |
dc.subject.keyword | decompensation | - |
dc.subject.keyword | health care | - |
dc.subject.keyword | liver cirrhosis | - |
dc.subject.keyword | utilization | - |
dc.contributor.alternativeName | Kim, Beom Kyung | - |
dc.contributor.affiliatedAuthor | 김범경 | - |
dc.citation.volume | 37 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 2154 | - |
dc.citation.endPage | 2163 | - |
dc.identifier.bibliographicCitation | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, Vol.37(11) : 2154-2163, 2022-11 | - |
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