Cited 2 times in
Declining trend of preemptive kidney transplantation and impact of pretransplant dialysis: a Korean nationwide prospective cohort study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 양재석 | - |
dc.contributor.author | 김명수 | - |
dc.date.accessioned | 2023-02-10T00:49:24Z | - |
dc.date.available | 2023-02-10T00:49:24Z | - |
dc.date.issued | 2021-12 | - |
dc.identifier.issn | 0934-0874 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/192397 | - |
dc.description.abstract | We evaluated the temporal trend of preemptive kidney transplantation (KT) and the effect of pretransplant dialysis duration on post-transplant outcomes. This was a nationwide cohort study of the first-time 3392 living donor KT (LDKT) recipients (2014-2019). The annual changes in proportion of preemptive KT, factors associated with preemptive KT, and post-transplant outcomes were analyzed. Preemptive KT was performed in 816 (24.1%) patients. Annual trend analysis revealed gradual decrease in preemptive KT over time (P = 0.042). Among the underlying causes of preemptive KT, the proportion of diabetes increased and that of glomerulonephritis decreased during the study period. Glomerulonephritis as the primary renal disease was a predictor of preemptive KT. Patients with pretransplant dialysis >6 months showed increased graft failure risk than preemptive KT in the subdistribution of hazard model for competing risk (adjusted hazard ratio [aHR], 2.53; 95% confidence interval [CI], 1.09-5.87; P = 0.031) and in propensity score-matched analysis (aHR, 2.45; 95% CI, 1.02-5.92; P = 0.034); however, pretransplant dialysis ≤6 months showed comparable graft survival with preemptive KT in both analyses. Preemptive KT declined over successive years, associated with an increase in diabetes and a decrease in glomerulonephritis as underlying causes of KT. Short period of dialysis less than 6 months does not affect graft survival compared with preemptive KT; however, longer dialysis decreases graft survival. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Blackwell Pub. | - |
dc.relation.isPartOf | TRANSPLANT INTERNATIONAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Graft Survival | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Kidney Failure, Chronic* / surgery | - |
dc.subject.MESH | Kidney Transplantation* | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Renal Dialysis | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Declining trend of preemptive kidney transplantation and impact of pretransplant dialysis: a Korean nationwide prospective cohort study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Jeong-Hoon Lim | - |
dc.contributor.googleauthor | Yena Jeon | - |
dc.contributor.googleauthor | Sang-Ho Lee | - |
dc.contributor.googleauthor | Yu Ho Lee | - |
dc.contributor.googleauthor | Jung Pyo Lee | - |
dc.contributor.googleauthor | Jaeseok Yang | - |
dc.contributor.googleauthor | Myoung Soo Kim | - |
dc.contributor.googleauthor | Hee-Yeon Jung | - |
dc.contributor.googleauthor | Ji-Young Choi | - |
dc.contributor.googleauthor | Sun-Hee Park | - |
dc.contributor.googleauthor | Chan-Duck Kim | - |
dc.contributor.googleauthor | Yong-Lim Kim | - |
dc.contributor.googleauthor | Jang-Hee Cho | - |
dc.contributor.googleauthor | Korean Organ Transplantation Registry Study Group | - |
dc.identifier.doi | 10.1111/tri.14135 | - |
dc.contributor.localId | A06130 | - |
dc.contributor.localId | A00424 | - |
dc.relation.journalcode | J02753 | - |
dc.identifier.eissn | 1432-2277 | - |
dc.identifier.pmid | 34633715 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1111/tri.14135 | - |
dc.subject.keyword | living donor kidney transplantation | - |
dc.subject.keyword | mortality | - |
dc.subject.keyword | preemptive kidney transplantation | - |
dc.subject.keyword | renal outcome | - |
dc.subject.keyword | trends | - |
dc.contributor.alternativeName | Yang, Jaeseok | - |
dc.contributor.affiliatedAuthor | 양재석 | - |
dc.contributor.affiliatedAuthor | 김명수 | - |
dc.citation.volume | 34 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 2769 | - |
dc.citation.endPage | 2780 | - |
dc.identifier.bibliographicCitation | TRANSPLANT INTERNATIONAL, Vol.34(12) : 2769-2780, 2021-12 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.