Cited 2 times in
A randomized split-face comparative study of long-pulsed alexandrite plus low-fluence Nd:YAG laser versus pulsed-dye laser in the treatment of rosacea
DC Field | Value | Language |
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dc.contributor.author | 오상호 | - |
dc.contributor.author | 김지희 | - |
dc.date.accessioned | 2022-12-22T05:11:28Z | - |
dc.date.available | 2022-12-22T05:11:28Z | - |
dc.date.issued | 2022-11 | - |
dc.identifier.issn | 0196-8092 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/192327 | - |
dc.description.abstract | Objectives: To compare the effectiveness of long-pulsed alexandrite laser (LPAL) with that of pulsed-dye laser (PDL) for rosacea. Methods: This was a single-blind randomized controlled trial on 27 patients who were clinically diagnosed with rosacea. Randomly assigned split face in each patient received four times monthly treatment of LPAL plus low-fluence Nd:YAG with the contralateral side serving as the control treated with PDL. At every visit, the erythema index (EI) was measured with skin analysis systems, and two independent dermatologists evaluated digital photographs for five-point global aesthetic improvement scale (GAIS). Results: The EI significantly decreased on both treated sides (LPAL 366.5 ± 101.0 vs. 295.8 ± 90.2, p < 0.001, PDL 369.0 ± 124.3 vs. 302.7 ± 92.1, p < 0.001) 1 month after fourth treatment (visit 5). Also 3 months after the fourth treatment (visit 6), the reduction in the EI was well maintained on both sides (LPAL 360.3 ± 96.8 vs. 282.0 ± 89.2, p < 0.001, PDL 364.3 ± 121.6 vs. 281.6 ± 97.8, p < 0.001). When comparing the improvement in the EI between the two groups, the percentage reduction in the EI on the LPAL-treated side was not inferior to the PDL-treated side (visit 5: LPAL 18.7 ± 15.7% vs. PDL 16.4 ± 12.9%, p = 0.501 and visit 6: LPAL 21.7 ± 13.9% vs. PDL 21.9 ± 15.2%, p = 0.943). The GAIS and patient satisfaction were comparable between the LPAL and PDL sides and did not show any significant difference. No serious adverse events occurred on either of the treated sides. Conclusion: This study showed that the decrease in EI in the treatment of rosacea was comparable between PDL and LPAL. Therefore, LPAL could be a promising alternative treatment option with good merits for rosacea, considering no consumables are required for device maintenance. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Wiley-Liss | - |
dc.relation.isPartOf | LASERS IN SURGERY AND MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Beryllium | - |
dc.subject.MESH | Erythema / etiology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Lasers, Dye* / therapeutic use | - |
dc.subject.MESH | Lasers, Solid-State* / therapeutic use | - |
dc.subject.MESH | Rosacea* / radiotherapy | - |
dc.subject.MESH | Single-Blind Method | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | A randomized split-face comparative study of long-pulsed alexandrite plus low-fluence Nd:YAG laser versus pulsed-dye laser in the treatment of rosacea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Dermatology (피부과학교실) | - |
dc.contributor.googleauthor | Sujin Park | - |
dc.contributor.googleauthor | Joo Hee Lee | - |
dc.contributor.googleauthor | Eunji Kang | - |
dc.contributor.googleauthor | Hyun Kim | - |
dc.contributor.googleauthor | Ji Young Kim | - |
dc.contributor.googleauthor | Eun Jung Lee | - |
dc.contributor.googleauthor | Yu Jeong Bae | - |
dc.contributor.googleauthor | Jihee Kim | - |
dc.contributor.googleauthor | Sang Ho Oh | - |
dc.identifier.doi | 10.1002/lsm.23605 | - |
dc.contributor.localId | A02370 | - |
dc.contributor.localId | A04732 | - |
dc.relation.journalcode | J02159 | - |
dc.identifier.eissn | 1096-9101 | - |
dc.identifier.pmid | 36183378 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1002/lsm.23605 | - |
dc.subject.keyword | Nd:YAG laser | - |
dc.subject.keyword | long pulse alexandrite laser | - |
dc.subject.keyword | pulse-dye laser | - |
dc.subject.keyword | rosacea | - |
dc.contributor.alternativeName | Oh, Sang Ho | - |
dc.contributor.affiliatedAuthor | 오상호 | - |
dc.contributor.affiliatedAuthor | 김지희 | - |
dc.citation.volume | 54 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 1217 | - |
dc.citation.endPage | 1225 | - |
dc.identifier.bibliographicCitation | LASERS IN SURGERY AND MEDICINE, Vol.54(9) : 1217-1225, 2022-11 | - |
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