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Generation of three TTN knock-out human induced pluripotent stem cell lines using CRISPR/Cas9 system

DC Field Value Language
dc.contributor.authorKang, Ji -Young-
dc.contributor.authorMun, Dasom-
dc.contributor.authorChun, Yumin-
dc.contributor.authorPark, Da -Seul-
dc.contributor.authorKim, Hyoeun-
dc.contributor.authorYun, Nuri-
dc.contributor.authorLee, Seung-Hyun-
dc.contributor.authorJoung, Boyoung-
dc.date.accessioned2022-12-22T04:59:19Z-
dc.date.available2022-12-22T04:59:19Z-
dc.date.created2023-01-27-
dc.date.issued2022-10-
dc.identifier.issn1873-5061-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/192267-
dc.description.abstractTTN mutations are the common genetic cause for various types of cardiomyopathies (e.g., dilated cardiomyopathy, hypertrophic cardiomyopathy, restrictive car-diomyopathy, and arrhythmogenic right ventricular cardiomyopathy) and skeletal myopathies. Here, we generated three TTN knock-out human induced pluripotent stem cell (iPSC) lines using CRISPR/Cas9 system. These cell lines, which exhibit normal karyotype, typical morphology and pluripotency, could provide useful platform for investigating the role of TTN in associated disorders.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherElsevier-
dc.relation.isPartOfSTEM CELL RESEARCH-
dc.relation.isPartOfSTEM CELL RESEARCH-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleGeneration of three TTN knock-out human induced pluripotent stem cell lines using CRISPR/Cas9 system-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorKang, Ji -Young-
dc.contributor.googleauthorMun, Dasom-
dc.contributor.googleauthorChun, Yumin-
dc.contributor.googleauthorPark, Da -Seul-
dc.contributor.googleauthorKim, Hyoeun-
dc.contributor.googleauthorYun, Nuri-
dc.contributor.googleauthorLee, Seung-Hyun-
dc.contributor.googleauthorJoung, Boyoung-
dc.identifier.doi10.1016/j.scr.2022.102901-
dc.relation.journalcodeJ02680-
dc.identifier.eissn1876-7753-
dc.identifier.pmid36037555-
dc.contributor.alternativeNameJoung, Bo Young-
dc.contributor.affiliatedAuthorKang, Ji -Young-
dc.contributor.affiliatedAuthorMun, Dasom-
dc.contributor.affiliatedAuthorChun, Yumin-
dc.contributor.affiliatedAuthorPark, Da -Seul-
dc.contributor.affiliatedAuthorKim, Hyoeun-
dc.contributor.affiliatedAuthorYun, Nuri-
dc.contributor.affiliatedAuthorLee, Seung-Hyun-
dc.contributor.affiliatedAuthorJoung, Boyoung-
dc.identifier.scopusid2-s2.0-85136540614-
dc.identifier.wosid000862847200001-
dc.citation.volume64-
dc.identifier.bibliographicCitationSTEM CELL RESEARCH, Vol.64, 2022-10-
dc.identifier.rimsid77111-
dc.type.rimsART-
dc.description.journalClass1-
dc.description.journalClass1-
dc.subject.keywordPlusTITIN-
dc.type.docTypeArticle-
dc.description.isOpenAccessY-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalWebOfScienceCategoryCell & Tissue Engineering-
dc.relation.journalWebOfScienceCategoryBiotechnology & Applied Microbiology-
dc.relation.journalWebOfScienceCategoryCell Biology-
dc.relation.journalResearchAreaCell Biology-
dc.relation.journalResearchAreaBiotechnology & Applied Microbiology-
dc.identifier.articleno102901-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Biochemistry and Molecular Biology (생화학-분자생물학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
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