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An induced pluripotent stem cell line (YCMi006-A) generated from a patient with hypertrophic cardiomyopathy who carries the ACTA1 mutation p.Ile343Met
DC Field | Value | Language |
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dc.contributor.author | 강석민 | - |
dc.contributor.author | 이승태 | - |
dc.contributor.author | 이승현 | - |
dc.contributor.author | 최종락 | - |
dc.contributor.author | 박상욱 | - |
dc.contributor.author | 원동주 | - |
dc.contributor.author | 오재원 | - |
dc.contributor.author | 김상우 | - |
dc.contributor.author | 김형표 | - |
dc.date.accessioned | 2022-12-22T03:33:31Z | - |
dc.date.available | 2022-12-22T03:33:31Z | - |
dc.date.issued | 2022-08 | - |
dc.identifier.issn | 1873-5061 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/191906 | - |
dc.description.abstract | Hypertrophic cardiomyopathy (HCM) is a common inherited cardiovascular disease and is characterized by hypertrophy of the left ventricle. We reprogrammed peripheral blood mononuclear cells (PBMCs) from a HCM patient into pluripotent stem cells (iPSC) (YCMi006-A) carrying a heterozygous c.1029C > G mutation in ACTA1. The YCMi006-A cells expressed high levels of pluripotent markers, had a normal 46XX karyotype and demonstrated the capacity to differentiate into derivatives of all three germ layers. This cell line can be a valuable tool for investigating the pathogenesis of HCM. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | STEM CELL RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Cardiomyopathy, Hypertrophic* / pathology | - |
dc.subject.MESH | Cell Line* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Induced Pluripotent Stem Cells* / metabolism | - |
dc.subject.MESH | Leukocytes, Mononuclear / metabolism | - |
dc.subject.MESH | Mutation / genetics | - |
dc.title | An induced pluripotent stem cell line (YCMi006-A) generated from a patient with hypertrophic cardiomyopathy who carries the ACTA1 mutation p.Ile343Met | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Hyoeun Kim | - |
dc.contributor.googleauthor | Hyeong-Jin Kim | - |
dc.contributor.googleauthor | Jaewon Oh | - |
dc.contributor.googleauthor | Seung-Tae Lee | - |
dc.contributor.googleauthor | Dongju Won | - |
dc.contributor.googleauthor | Hyo-Kyoung Choi | - |
dc.contributor.googleauthor | Jong Rak Choi | - |
dc.contributor.googleauthor | Sangwoo Kim | - |
dc.contributor.googleauthor | Hyoung-Pyo Kim | - |
dc.contributor.googleauthor | Seok-Jun Kim | - |
dc.contributor.googleauthor | Sahng Wook Park | - |
dc.contributor.googleauthor | Seok-Min Kang | - |
dc.contributor.googleauthor | Seung-Hyun Lee | - |
dc.identifier.doi | 10.1016/j.scr.2022.102874 | - |
dc.contributor.localId | A00037 | - |
dc.contributor.localId | A04627 | - |
dc.contributor.localId | A02932 | - |
dc.contributor.localId | A04182 | - |
dc.contributor.localId | A01487 | - |
dc.contributor.localId | A05763 | - |
dc.contributor.localId | A02395 | - |
dc.contributor.localId | A00524 | - |
dc.contributor.localId | A01163 | - |
dc.relation.journalcode | J02680 | - |
dc.identifier.eissn | 1876-7753 | - |
dc.identifier.pmid | 35917599 | - |
dc.contributor.alternativeName | Kang, Seok Min | - |
dc.contributor.affiliatedAuthor | 강석민 | - |
dc.contributor.affiliatedAuthor | 이승태 | - |
dc.contributor.affiliatedAuthor | 이승현 | - |
dc.contributor.affiliatedAuthor | 최종락 | - |
dc.contributor.affiliatedAuthor | 박상욱 | - |
dc.contributor.affiliatedAuthor | 원동주 | - |
dc.contributor.affiliatedAuthor | 오재원 | - |
dc.contributor.affiliatedAuthor | 김상우 | - |
dc.contributor.affiliatedAuthor | 김형표 | - |
dc.citation.volume | 63 | - |
dc.citation.startPage | 102874 | - |
dc.identifier.bibliographicCitation | STEM CELL RESEARCH, Vol.63 : 102874, 2022-08 | - |
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