Cited 11 times in
Cancer Incidence Among Adults With HIV in a Population-Based Cohort in Korea
DC Field | Value | Language |
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dc.contributor.author | 김정호 | - |
dc.contributor.author | 최준용 | - |
dc.date.accessioned | 2022-12-22T03:18:59Z | - |
dc.date.available | 2022-12-22T03:18:59Z | - |
dc.date.issued | 2022-08 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/191843 | - |
dc.description.abstract | Importance: In combination with a decreased risk of AIDS-defining cancers and improved survival of people infected with HIV, the burden of non-AIDS-defining cancer has increased markedly. Although a substantial number of studies have measured the cancer risk among people with HIV in developed countries, little research has been conducted on the risk of cancer in HIV-infected people in Asia. Objective: To examine the cancer incidence and the estimated risk of cancer among people in Korea infected with HIV compared with the general population. Design, setting, and participants: This retrospective cohort study evaluated patients without cancer newly diagnosed with HIV from January 1, 2006, to December 31, 2018, using a nationwide population-based claims database embedded in the National Health Insurance Service database. Data were analyzed between December 6, 2021, and February 28, 2022. Exposures: Infection with HIV. Main outcomes and measures: Cancer incidence and standardized incidence rate (SIR) through indirect standardization. Results: A total of 11 552 individuals without cancer (10 444 male [90.4%]; mean [SD] age, 39.9 [11.2] years) diagnosed with HIV were identified. The SIR for all cancers was 1.68 (95% CI, 1.50-1.87) in men and 1.26 (95% CI, 0.89-1.64) in women. In men, the highest SIRs were for Kaposi sarcoma (SIR, 349.10; 95% CI, 196.10-502.20) and anal cancer (SIR, 104.20; 95% CI, 55.56-149.90). The incidence of non-Hodgkin lymphoma (SIR, 15.62; 95% CI, 11.85-19.39), Hodgkin lymphoma (SIR, 16.67; 95% CI, 4.32-29.02), and oropharyngeal cancer (SIR, 2.97; 95% CI, 1.36-4.58) in men infected with HIV was higher than in the general population. In women infected with HIV, an increased incidence of cervical cancer (SIR, 4.98; 95% CI, 1.29-8.66) and non-Hodgkin lymphoma (SIR, 11.78; 95% CI, 2.35-21.21) compared with the general population was observed. The SIR of thyroid cancer in patients with HIV was lower than in the general population in both men (SIR, 0.63; 95% CI, 0.27-0.99) and women (SIR, 0.48; 95% CI, 0.06-0.90). Conclusions and relevance: In this cohort study, cancer risks, especially AIDS-defining cancer and virus-related cancer, were elevated in people with HIV. Efforts for cancer prevention, screening, and better accessibility to medical care in HIV-infected people are warranted. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | American Medical Association | - |
dc.relation.isPartOf | JAMA NETWORK OPEN | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | HIV Infections* / complications | - |
dc.subject.MESH | HIV Infections* / epidemiology | - |
dc.subject.MESH | Hodgkin Disease* / complications | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Lymphoma, Non-Hodgkin* / epidemiology | - |
dc.subject.MESH | Lymphoma, Non-Hodgkin* / etiology | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Republic of Korea / epidemiology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.title | Cancer Incidence Among Adults With HIV in a Population-Based Cohort in Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Boyoung Park | - |
dc.contributor.googleauthor | Kyoung Hwan Ahn | - |
dc.contributor.googleauthor | Yunsu Choi | - |
dc.contributor.googleauthor | Jung Ho Kim | - |
dc.contributor.googleauthor | Hye Seong | - |
dc.contributor.googleauthor | Youn Jeong Kim | - |
dc.contributor.googleauthor | Jun Young Choi | - |
dc.contributor.googleauthor | Joon Young Song | - |
dc.contributor.googleauthor | Eunjung Lee | - |
dc.contributor.googleauthor | Yoon Hee Jun | - |
dc.contributor.googleauthor | Young Kyung Yoon | - |
dc.contributor.googleauthor | Won Suk Choi | - |
dc.contributor.googleauthor | Myungsun Lee | - |
dc.contributor.googleauthor | Jaehyun Seong | - |
dc.contributor.googleauthor | Shin-Woo Kim | - |
dc.identifier.doi | 10.1001/jamanetworkopen.2022.24897 | - |
dc.contributor.localId | A00902 | - |
dc.contributor.localId | A04191 | - |
dc.relation.journalcode | J03719 | - |
dc.identifier.eissn | 2574-3805 | - |
dc.identifier.pmid | 35917123 | - |
dc.contributor.alternativeName | Kim, Jung Ho | - |
dc.contributor.affiliatedAuthor | 김정호 | - |
dc.contributor.affiliatedAuthor | 최준용 | - |
dc.citation.volume | 5 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | e2224897 | - |
dc.identifier.bibliographicCitation | JAMA NETWORK OPEN, Vol.5(8) : e2224897, 2022-08 | - |
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