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Endoscopic variceal obturation and retrograde transvenous obliteration for acute gastric cardiofundal variceal bleeding in liver cirrhosis
DC Field | Value | Language |
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dc.contributor.author | 김승업 | - |
dc.date.accessioned | 2022-12-22T02:30:10Z | - |
dc.date.available | 2022-12-22T02:30:10Z | - |
dc.date.issued | 2022-07 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/191609 | - |
dc.description.abstract | Background/aims: We retrospectively compared the effect of endoscopic variceal obturation (EVO) and retrograde transvenous obliteration (RTO) in acute cardiofundal variceal bleeding. Methods: Patients with acute cardiofundal variceal bleeding treated with EVO or RTO at two hospitals were included. Results: Ninety patients treated with EVO and 86 treated with RTO were analyzed. The mean model for end-stage liver disease score was significantly higher in EVO group than in RTO group (13.5 vs. 11.7, P = 0.016). The bleeding control rates were high (97.8% vs. 96.5%), and the treatment-related complication rates were low in both EVO and RTO groups (2.2% vs. 3.5%). During the median follow-up of 18.0 months, gastric variceal (GV) and esophageal variceal rebleeding occurred in 34 (19.3%) and 7 (4.0%) patients, respectively. The all-variceal rebleeding rates were comparable between EVO and RTO groups (32.4% vs. 20.8% at 2-year, P = 0.150), while the GV rebleeding rate was significantly higher in EVO group than in RTO group (32.4% vs. 12.8% at 2-year, P = 0.003). On propensity score-matched analysis (71 patients in EVO vs. 71 patients in RTO group), both all-variceal and GV rebleeding rates were significantly higher in EVO group than in RTO group (all P < 0.05). In Cox regression analysis, EVO (vs. RTO) was the only significant predictor of higher GV rebleeding risk (hazard ratio 3.132, P = 0.005). The mortality rates were similar between two groups (P = 0.597). Conclusions: Both EVO and RTO effectively controlled acute cardiofundal variceal bleeding. RTO was superior to EVO in preventing all-variceal and GV rebleeding after treatment, with similar survival outcomes. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | BioMed Central | - |
dc.relation.isPartOf | BMC GASTROENTEROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Balloon Occlusion* / adverse effects | - |
dc.subject.MESH | End Stage Liver Disease* | - |
dc.subject.MESH | Esophageal and Gastric Varices* / complications | - |
dc.subject.MESH | Esophageal and Gastric Varices* / therapy | - |
dc.subject.MESH | Gastrointestinal Hemorrhage / etiology | - |
dc.subject.MESH | Gastrointestinal Hemorrhage / therapy | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Liver Cirrhosis / complications | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Severity of Illness Index | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Endoscopic variceal obturation and retrograde transvenous obliteration for acute gastric cardiofundal variceal bleeding in liver cirrhosis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Han Ah Lee | - |
dc.contributor.googleauthor | Jungwon Kwak | - |
dc.contributor.googleauthor | Sung Bum Cho | - |
dc.contributor.googleauthor | Young-Sun Lee | - |
dc.contributor.googleauthor | Young Kul Jung | - |
dc.contributor.googleauthor | Ji Hoon Kim | - |
dc.contributor.googleauthor | Seung Up Kim | - |
dc.contributor.googleauthor | Hyonggin An | - |
dc.contributor.googleauthor | Hyung Joon Yim | - |
dc.contributor.googleauthor | Jong Eun Yeon | - |
dc.contributor.googleauthor | Yeon Seok Seo | - |
dc.identifier.doi | 10.1186/s12876-022-02428-1 | - |
dc.contributor.localId | A00654 | - |
dc.relation.journalcode | J00356 | - |
dc.identifier.eissn | 1471-230X | - |
dc.identifier.pmid | 35883035 | - |
dc.subject.keyword | Balloon-occluded retrograde transvenous obliteration | - |
dc.subject.keyword | Portal hypertension | - |
dc.subject.keyword | Prevention | - |
dc.subject.keyword | Rebleeding | - |
dc.subject.keyword | Vascular plug-assisted retrograde transvenous obliteration | - |
dc.contributor.alternativeName | Kim, Seung Up | - |
dc.contributor.affiliatedAuthor | 김승업 | - |
dc.citation.volume | 22 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 355 | - |
dc.identifier.bibliographicCitation | BMC GASTROENTEROLOGY, Vol.22(1) : 355, 2022-07 | - |
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