Cited 20 times in
Association of rhythm control with incident dementia among patients with atrial fibrillation: a nationwide population-based cohort study
DC Field | Value | Language |
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dc.contributor.author | 김태훈 | - |
dc.contributor.author | 박희남 | - |
dc.contributor.author | 정보영 | - |
dc.contributor.author | 이문형 | - |
dc.contributor.author | 유희태 | - |
dc.contributor.author | 유승찬 | - |
dc.contributor.author | 김대훈 | - |
dc.date.accessioned | 2022-12-22T01:21:04Z | - |
dc.date.available | 2022-12-22T01:21:04Z | - |
dc.date.issued | 2022-01 | - |
dc.identifier.issn | 0002-0729 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/191172 | - |
dc.description.abstract | Background: Atrial fibrillation (AF) increases the risk of dementia, and catheter ablation of AF may be associated with a lower risk of dementia. We investigated the association of a rhythm-control strategy for AF with the risk of dementia, compared with a rate-control strategy. Methods: This population-based cohort study included 41,135 patients with AF on anticoagulation who were newly treated with rhythm-control (anti-arrhythmic drugs or ablation) or rate-control strategies between 1 January 2005 and 31 December 2015 from the Korean National Health Insurance Service database. The primary outcome was all-cause dementia, which was compared using propensity score overlap weighting. Results: In the study population (46.7% female; median age: 68 years), a total of 4,039 patients were diagnosed with dementia during a median follow-up of 51.7 months. Rhythm control, compared with rate control, was associated with decreased dementia risk (weighted incidence rate: 21.2 versus 25.2 per 1,000 person-years; subdistribution hazard ratio [sHR] 0.86, 95% confidence interval [CI] 0.80-0.93). The associations between rhythm control and decreased dementia risk were consistently observed even after censoring for incident stroke (sHR 0.89, 95% CI 0.82-0.97) and were more pronounced in relatively younger patients and those with lower CHA2DS2-VASc scores. Among dementia subtypes, rhythm control was associated with a lower risk of Alzheimer's disease (sHR 0.86, 95% CI 0.79-0.95). Conclusions: Among anticoagulated patients with AF, rhythm control was associated with a lower risk of dementia, compared with rate control. Initiating rhythm control in AF patients with fewer stroke risk factors might help prevent subsequent dementia. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Oxford | - |
dc.relation.isPartOf | AGE AND AGEING | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Atrial Fibrillation* / diagnosis | - |
dc.subject.MESH | Atrial Fibrillation* / drug therapy | - |
dc.subject.MESH | Atrial Fibrillation* / epidemiology | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Dementia* / diagnosis | - |
dc.subject.MESH | Dementia* / epidemiology | - |
dc.subject.MESH | Dementia* / prevention & control | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Risk Assessment | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Stroke* / diagnosis | - |
dc.subject.MESH | Stroke* / epidemiology | - |
dc.subject.MESH | Stroke* / prevention & control | - |
dc.title | Association of rhythm control with incident dementia among patients with atrial fibrillation: a nationwide population-based cohort study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Daehoon Kim | - |
dc.contributor.googleauthor | Pil-Sung Yang | - |
dc.contributor.googleauthor | Seng Chan You | - |
dc.contributor.googleauthor | Jung-Hoon Sung | - |
dc.contributor.googleauthor | Eunsun Jang | - |
dc.contributor.googleauthor | Hee Tae Yu | - |
dc.contributor.googleauthor | Tae-Hoon Kim | - |
dc.contributor.googleauthor | Hui-Nam Pak | - |
dc.contributor.googleauthor | Moon-Hyoung Lee | - |
dc.contributor.googleauthor | Gregory Y H Lip | - |
dc.contributor.googleauthor | Boyoung Joung | - |
dc.identifier.doi | 10.1093/ageing/afab248 | - |
dc.contributor.localId | A01085 | - |
dc.contributor.localId | A01776 | - |
dc.contributor.localId | A03609 | - |
dc.contributor.localId | A02766 | - |
dc.contributor.localId | A02535 | - |
dc.contributor.localId | A02478 | - |
dc.contributor.localId | A00373 | - |
dc.relation.journalcode | J03574 | - |
dc.identifier.eissn | 1468-2834 | - |
dc.identifier.pmid | 35061873 | - |
dc.identifier.url | https://academic.oup.com/ageing/article-lookup/doi/10.1093/ageing/afab248 | - |
dc.subject.keyword | atrial fibrillation | - |
dc.subject.keyword | dementia | - |
dc.subject.keyword | older people | - |
dc.subject.keyword | rate control | - |
dc.subject.keyword | rhythm control | - |
dc.contributor.alternativeName | Kim, Tae-Hoon | - |
dc.contributor.affiliatedAuthor | 김태훈 | - |
dc.contributor.affiliatedAuthor | 박희남 | - |
dc.contributor.affiliatedAuthor | 정보영 | - |
dc.contributor.affiliatedAuthor | 이문형 | - |
dc.contributor.affiliatedAuthor | 유희태 | - |
dc.contributor.affiliatedAuthor | 유승찬 | - |
dc.contributor.affiliatedAuthor | 김대훈 | - |
dc.citation.volume | 51 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | afab248 | - |
dc.identifier.bibliographicCitation | AGE AND AGEING, Vol.51(1) : afab248, 2022-01 | - |
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