Cited 4 times in
Features and diversity of symptoms of moyamoya disease in adolescents: A cluster analysis
DC Field | Value | Language |
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dc.contributor.author | 심규원 | - |
dc.date.accessioned | 2022-11-24T00:44:29Z | - |
dc.date.available | 2022-11-24T00:44:29Z | - |
dc.date.issued | 2021-05 | - |
dc.identifier.issn | 0309-2402 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/190928 | - |
dc.description.abstract | Aims: The purpose of this study is to explore the symptoms experienced by adolescents with moyamoya disease and to identify the characteristics of each symptom cluster associated with moyamoya disease. Design: A retrospective and descriptive design, which is a secondary data analysis study based on electronic medical record data from hospitals. Methods: To assess the symptoms associated with moyamoya disease, a qualitative study was conducted on 12 adolescents, 12 caregivers and 12 experts on moyamoya disease. According to a qualitative study, 12 main symptoms (limb weakness, numbness, pins and needles, difficulty in speech, blurred vision, facial paralysis, hand tremors, involuntary movements, convulsions, dizziness, nausea/vomiting and headaches) were selected. Data were collected around these symptoms. The data collection was carried out through the Electronic Medical Record (EMR) data of 303 adolescents aged 13-19 who were diagnosed with moyamoya disease (ICD 10 Code: I67.5) between January 2010-December 2019 in a hospital in Seoul, South Korea. Cluster analysis was applied to identify symptom clusters with the hierarchical cluster agglomerative approach. We used the log-likelihood distance to measure the similarity of variables. Proximity between groups of variables was measured using the two-step method. Results: The physical symptoms experienced by adolescents with moyamoya disease were 'limb weakness' - the most common - followed by a 'headache,' 'difficulty in speech,' and 'nausea/vomiting.' A total of five symptom clusters were derived: cluster 1 was characterized by 'limb weakness'; cluster 2 participants were asymptomatic or experienced 'convulsions'; cluster 3 experienced 'difficulty in speech' and 'facial paralysis'; cluster 4 is prone to 'dizziness' and 'pins and needles'; and cluster 5 displays 'headaches' and 'nausea/vomiting'. Conclusion: This study offers a multidimensional approach for identifying differences in clinical symptoms of moyamoya disease among adolescents. Impact: These results will help provide interventions concerning the characteristics of the symptoms of moyamoya disease among adolescents. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Blackwell Scientific Publications | - |
dc.relation.isPartOf | JOURNAL OF ADVANCED NURSING | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Cluster Analysis | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Moyamoya Disease* / epidemiology | - |
dc.subject.MESH | Nausea | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Retrospective Studies | - |
dc.title | Features and diversity of symptoms of moyamoya disease in adolescents: A cluster analysis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurosurgery (신경외과학교실) | - |
dc.contributor.googleauthor | Won-Oak Oh | - |
dc.contributor.googleauthor | Kyu Won Shim | - |
dc.contributor.googleauthor | Insun Yeom | - |
dc.contributor.googleauthor | Il Tae Park | - |
dc.contributor.googleauthor | YooJin Heo | - |
dc.identifier.doi | 10.1111/jan.14723 | - |
dc.contributor.localId | A02187 | - |
dc.relation.journalcode | J01222 | - |
dc.identifier.eissn | 1365-2648 | - |
dc.identifier.pmid | 33426712 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1111/jan.14723 | - |
dc.subject.keyword | adolescents | - |
dc.subject.keyword | cluster analysis | - |
dc.subject.keyword | moyamoya disease | - |
dc.subject.keyword | nursing | - |
dc.subject.keyword | symptom cluster | - |
dc.contributor.alternativeName | Shim, Kyu Won | - |
dc.contributor.affiliatedAuthor | 심규원 | - |
dc.citation.volume | 77 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 2319 | - |
dc.citation.endPage | 2327 | - |
dc.identifier.bibliographicCitation | JOURNAL OF ADVANCED NURSING, Vol.77(5) : 2319-2327, 2021-05 | - |
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