Cited 10 times in
Comparison of Sugammadex Dose for Intraoperative Neuromonitoring in Thyroid Surgery: A Randomized Controlled Trial
DC Field | Value | Language |
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dc.contributor.author | 이지원 | - |
dc.date.accessioned | 2022-11-24T00:35:34Z | - |
dc.date.available | 2022-11-24T00:35:34Z | - |
dc.date.issued | 2021-09 | - |
dc.identifier.issn | 0023-852X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/190791 | - |
dc.description.abstract | Objectives/hypothesis: To compare effect of 1 and 2 mg/kg of sugammadex on the incidence of intraoperative bucking and intraoperative neuromonitoring (IONM) quality in thyroid surgery. Study design: Randomized controlled trial. Methods: Patients qualified for thyroid surgery with IONM were eligible for this double-blind, randomized, controlled trial. After tracheal intubation with 0.6 mg/kg rocuronium, 1 or 2 mg/kg of sugammadex was administered to patients in group I or II, respectively. The quality of the IONM for the external branch of the superior laryngeal nerve (EBSLN) was evaluated (strong/intermediate/weak). The initial amplitude of electromyography for the vagus nerve (V1) and the recurrent laryngeal nerve (R1) were recorded. Intraoperative bucking movements was recorded. Results: A total of 102 patients (51 in each group) completed the study. Time from sugammadex administration to initial checking for the EBSLN was not different between group I and II (25.0 ± 7.9 vs. 25.5 ± 9.0 minutes, P = .788). There was no difference in the neuromonitoring quality for the EBSLN between group I and II (strong/intermediate/weak: 46/5/0 vs. 50/1/0, P = .205). The amplitudes of V1 (1,086.3 ± 673.3 μV vs. 1,161.8 ± 727.5 μV, P = .588) and R1 (1,328.2 ± 934.1 μV vs. 1,410.5 ± 919.6 μV, P = .655) were comparable between the groups. Patients who experienced bucking were significantly fewer in the group I than the group II (13.7% vs. 35.3%, P = .020). Conclusion: A dose of 1 mg/kg sugammadex induced less bucking than 2 m/kg while providing comparable IONM quality during thyroid surgery. Level of evidence: 2 Laryngoscope, 131:2154-2159, 2021. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Wiley-Blackwell | - |
dc.relation.isPartOf | LARYNGOSCOPE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Central Nervous System / drug effects | - |
dc.subject.MESH | Central Nervous System / physiology | - |
dc.subject.MESH | Dose-Response Relationship, Drug | - |
dc.subject.MESH | Double-Blind Method | - |
dc.subject.MESH | Electromyography / methods | - |
dc.subject.MESH | Evaluation Studies as Topic | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intraoperative Care / methods* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Monitoring, Intraoperative / instrumentation* | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Recurrent Laryngeal Nerve / physiology | - |
dc.subject.MESH | Recurrent Laryngeal Nerve Injuries / etiology* | - |
dc.subject.MESH | Recurrent Laryngeal Nerve Injuries / prevention & control | - |
dc.subject.MESH | Respiratory Distress Syndrome / chemically induced | - |
dc.subject.MESH | Respiratory Distress Syndrome / epidemiology | - |
dc.subject.MESH | Sugammadex / administration & dosage | - |
dc.subject.MESH | Sugammadex / adverse effects* | - |
dc.subject.MESH | Thyroid Gland / surgery* | - |
dc.subject.MESH | Vagus Nerve / physiology | - |
dc.title | Comparison of Sugammadex Dose for Intraoperative Neuromonitoring in Thyroid Surgery: A Randomized Controlled Trial | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) | - |
dc.contributor.googleauthor | Young Jun Chai | - |
dc.contributor.googleauthor | Jung-Man Lee | - |
dc.contributor.googleauthor | Dongwook Won | - |
dc.contributor.googleauthor | Jiwon Lee | - |
dc.contributor.googleauthor | Jin-Young Hwang | - |
dc.contributor.googleauthor | Tae Kyong Kim | - |
dc.contributor.googleauthor | Jee-Eun Chang | - |
dc.contributor.googleauthor | Hyerim Kim | - |
dc.contributor.googleauthor | Hyo Jun Yang | - |
dc.contributor.googleauthor | Seong-Won Min | - |
dc.identifier.doi | 10.1002/lary.29515 | - |
dc.contributor.localId | A06070 | - |
dc.relation.journalcode | J02156 | - |
dc.identifier.eissn | 1531-4995 | - |
dc.identifier.pmid | 33720388 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1002/lary.29515 | - |
dc.subject.keyword | Neural monitoring | - |
dc.subject.keyword | recurrent laryngeal nerve | - |
dc.subject.keyword | sugammadex | - |
dc.subject.keyword | thyroid surgery | - |
dc.subject.keyword | vocal cord paralysis | - |
dc.contributor.alternativeName | Lee, Jiwon | - |
dc.contributor.affiliatedAuthor | 이지원 | - |
dc.citation.volume | 131 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 2154 | - |
dc.citation.endPage | 2159 | - |
dc.identifier.bibliographicCitation | LARYNGOSCOPE, Vol.131(9) : 2154-2159, 2021-09 | - |
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