Cited 4 times in
Association of Urinary Potassium Excretion with Blood Pressure Variability and Cardiovascular Outcomes in Patients with Pre-Dialysis Chronic Kidney Disease
DC Field | Value | Language |
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dc.contributor.author | 한승혁 | - |
dc.date.accessioned | 2022-09-14T01:52:43Z | - |
dc.date.available | 2022-09-14T01:52:43Z | - |
dc.date.issued | 2021-12 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/190660 | - |
dc.description.abstract | Dietary potassium intake is a dilemma in patients with chronic kidney disease (CKD). We investigated the association of urine potassium excretion, a surrogate for dietary potassium intake, with blood pressure variability (BPV) and cardiovascular (CV) outcomes in patients with pre-dialysis CKD. A total of 1860 participants from a cohort of pre-dialysis CKD (KNOW-CKD) patients were divided into the quartiles by spot urine potassium-to-creatinine ratio. The first quartile (26.423 ± 5.731 mmol/gCr) was defined as low urine potassium excretion. Multivariate linear regression analyses revealed an independent association of low urine potassium excretion with high BPV (adjusted β coefficient 1.163, 95% confidence interval 0.424 to 1.901). Cox regression analyses demonstrated that, compared to high urine potassium excretion, low urine potassium excretion is associated with increased risk of CV events (adjusted hazard ratio 2.502, 95% confidence interval 1.162 to 5.387) but not with all-cause mortality. In conclusion, low urine potassium excretion is associated with high BPV and increased risk of CV events in patients with pre-dialysis CKD. The restriction of dietary potassium intake should be individualized in patients with pre-dialysis CKD. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | MDPI Publishing | - |
dc.relation.isPartOf | NUTRIENTS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Blood Pressure* | - |
dc.subject.MESH | Cardiovascular Diseases / epidemiology* | - |
dc.subject.MESH | Cardiovascular Diseases / mortality | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Creatinine / urine | - |
dc.subject.MESH | Dialysis / methods | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypertension / epidemiology | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Potassium / administration & dosage | - |
dc.subject.MESH | Potassium / urine* | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Renal Insufficiency, Chronic / epidemiology | - |
dc.subject.MESH | Renal Insufficiency, Chronic / mortality | - |
dc.subject.MESH | Renal Insufficiency, Chronic / physiopathology | - |
dc.subject.MESH | Renal Insufficiency, Chronic / urine* | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Sodium / urine | - |
dc.title | Association of Urinary Potassium Excretion with Blood Pressure Variability and Cardiovascular Outcomes in Patients with Pre-Dialysis Chronic Kidney Disease | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Sang Heon Suh | - |
dc.contributor.googleauthor | Su Hyun Song | - |
dc.contributor.googleauthor | Tae Ryom Oh | - |
dc.contributor.googleauthor | Hong Sang Choi | - |
dc.contributor.googleauthor | Chang Seong Kim | - |
dc.contributor.googleauthor | Eun Hui Bae | - |
dc.contributor.googleauthor | Kook-Hwan Oh | - |
dc.contributor.googleauthor | Joongyub Lee | - |
dc.contributor.googleauthor | Seung Hyeok Han | - |
dc.contributor.googleauthor | Yeong Hoon Kim | - |
dc.contributor.googleauthor | Dong-Wan Chae | - |
dc.contributor.googleauthor | Seong Kwon Ma | - |
dc.contributor.googleauthor | Soo Wan Kim | - |
dc.identifier.doi | 10.3390/nu13124443 | - |
dc.contributor.localId | A04304 | - |
dc.relation.journalcode | J02396 | - |
dc.identifier.eissn | 2072-6643 | - |
dc.identifier.pmid | 34959995 | - |
dc.subject.keyword | blood pressure variability | - |
dc.subject.keyword | chronic kidney disease | - |
dc.subject.keyword | dietary potassium intake | - |
dc.subject.keyword | extended major cardiovascular event | - |
dc.subject.keyword | urine potassium | - |
dc.contributor.alternativeName | Han, Seung Hyeok | - |
dc.contributor.affiliatedAuthor | 한승혁 | - |
dc.citation.volume | 13 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 4443 | - |
dc.identifier.bibliographicCitation | NUTRIENTS, Vol.13(12) : 4443, 2021-12 | - |
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