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Comparison of two-year clinical outcomes according to glycemic status and renal function in patients with acute myocardial infarction following implantation of new-generation drug-eluting stents

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dc.contributor.author고영국-
dc.contributor.author김병극-
dc.contributor.author김중선-
dc.contributor.author장양수-
dc.contributor.author최동훈-
dc.contributor.author홍명기-
dc.contributor.author홍성진-
dc.contributor.author안철민-
dc.date.accessioned2022-09-14T01:44:48Z-
dc.date.available2022-09-14T01:44:48Z-
dc.date.issued2021-11-
dc.identifier.issn1056-8727-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/190596-
dc.description.abstractAim: We compared the 2-year clinical outcomes between prediabetes and type 2 diabetes mellitus (T2DM) in patients with acute myocardial infarction (AMI) and chronic kidney disease (CKD) after the successful implantation of new-generation drug-eluting stents. Methods: A total of 11,961 AMI patients were classified into group A (estimated glomerular filtration rate [eGFR] < 60 ml/min/1.73m2, n = 2271) and group B (eGFR ≥60 ml/min/1.73 m2, n = 9690). These two groups were sub-classified into normoglycemia, prediabetes, and T2DM. The occurrence of major adverse cardiac events (MACE), defined as all-cause death, recurrent MI (re-MI), and any repeat revascularization was evaluated. Results: In group A, the MACE (p = 0.016 and p = 0.004, respectively) and all-cause death (p = 0.044, and p = 0.031, respectively) rates; in groups B, the MACE, all-cause death, and cardiac death rates, were significantly higher in the prediabetes and T2DM groups than in the normoglycemia group. The re-MI and any repeat revascularization rates were significantly higher in the T2DM group than in the normoglycemia group. The MACE, all-cause death, and cardiac death rates in group A were significantly higher than those in all three glycemic subgroups of group B. Both in group A and B, the major clinical outcomes were not significantly different between the prediabetes and T2DM groups. Conclusions: AMI patients, both with prediabetes and T2DM, showed a higher mortality rate than those with normoglycemia regardless of the degree of eGFR.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherElsevier Science Pub. Co.-
dc.relation.isPartOfJOURNAL OF DIABETES AND ITS COMPLICATIONS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHDiabetes Mellitus, Type 2* / complications-
dc.subject.MESHDiabetes Mellitus, Type 2* / epidemiology-
dc.subject.MESHDrug-Eluting Stents*-
dc.subject.MESHHumans-
dc.subject.MESHKidney / physiology-
dc.subject.MESHKidney / physiopathology-
dc.subject.MESHMortality-
dc.subject.MESHMyocardial Infarction* / complications-
dc.subject.MESHMyocardial Infarction* / epidemiology-
dc.subject.MESHPercutaneous Coronary Intervention-
dc.subject.MESHPrediabetic State* / complications-
dc.subject.MESHPrediabetic State* / epidemiology-
dc.subject.MESHTreatment Outcome-
dc.titleComparison of two-year clinical outcomes according to glycemic status and renal function in patients with acute myocardial infarction following implantation of new-generation drug-eluting stents-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorYong Hoon Kim-
dc.contributor.googleauthorAe-Young Her-
dc.contributor.googleauthorMyung Ho Jeong-
dc.contributor.googleauthorByeong-Keuk Kim-
dc.contributor.googleauthorSung-Jin Hong-
dc.contributor.googleauthorSeunghwan Kim-
dc.contributor.googleauthorChul-Min Ahn-
dc.contributor.googleauthorJung-Sun Kim-
dc.contributor.googleauthorYoung-Guk Ko-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorMyeong-Ki Hong-
dc.contributor.googleauthorYangsoo Jang-
dc.identifier.doi10.1016/j.jdiacomp.2021.108019-
dc.contributor.localIdA00127-
dc.contributor.localIdA00493-
dc.contributor.localIdA00961-
dc.contributor.localIdA05648-
dc.contributor.localIdA03448-
dc.contributor.localIdA04053-
dc.contributor.localIdA04391-
dc.contributor.localIdA04403-
dc.relation.journalcodeJ01376-
dc.identifier.eissn1873-460X-
dc.identifier.pmid34400082-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S1056872721002282-
dc.subject.keywordChronic kidney disease-
dc.subject.keywordDiabetes-
dc.subject.keywordMyocardial infarction-
dc.subject.keywordPrediabetes-
dc.contributor.alternativeNameKo, Young Guk-
dc.contributor.affiliatedAuthor고영국-
dc.contributor.affiliatedAuthor김병극-
dc.contributor.affiliatedAuthor김중선-
dc.contributor.affiliatedAuthor장양수-
dc.contributor.affiliatedAuthor최동훈-
dc.contributor.affiliatedAuthor홍명기-
dc.contributor.affiliatedAuthor홍성진-
dc.citation.volume35-
dc.citation.number11-
dc.citation.startPage108019-
dc.identifier.bibliographicCitationJOURNAL OF DIABETES AND ITS COMPLICATIONS, Vol.35(11) : 108019, 2021-11-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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