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1980–2019년 기간 동안 소아청소년 알레르기질환에서 항원 감작의 변화
DC Field | Value | Language |
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dc.contributor.author | 김경원 | - |
dc.contributor.author | 김민정 | - |
dc.contributor.author | 김수연 | - |
dc.contributor.author | 김윤희 | - |
dc.contributor.author | 박미르 | - |
dc.contributor.author | 손명현 | - |
dc.contributor.author | 이용주 | - |
dc.contributor.author | 정재화 | - |
dc.date.accessioned | 2022-09-14T01:38:27Z | - |
dc.date.available | 2022-09-14T01:38:27Z | - |
dc.date.issued | 2021-10 | - |
dc.identifier.issn | 2288-0402 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/190554 | - |
dc.description.abstract | Purpose Allergen sensitization is constantly changing, and understanding these changes can help manage and prevent allergic diseases. This research analyzed and compared the changes in allergen sensitization in children diagnosed with allergic diseases using the skin test and the multiple allergen simultaneous test. Methods We retrospectively analyzed the data on children who were diagnosed with allergic diseases and received immunotherapy at Yonsei Medical Center from 1980 to 1998 and they were screened for allergen sensitization at Severance Hospital from 2005 to 2019. Results Between 1980 and 1998, and between 2005 and 2019, data on 3,205 (male, 70.3%; mean age, 7.2±2.9 years) and 15,318 children (male, 62.8%; mean age, 8.8±4.5 years) were analyzed. The sensitized allergens that appeared in the 1980–1998 included Dermatophagoides farinae (91.0%), Dermatophagoides pteronyssinus (76.3%), cockroach (13.5%), and Alternaria (11.5%), in order of frequency; further, the sensitized allergens that appeared in the 2005–2019 included D. farinae (45.0%), D. pteronyssinus (39.6%), cat dander (12.2%), and dog dander (9.1%), in order of frequency. D. farinae and D. pteronyssinus demonstrated the highest sensitization rates, although the rates decreased gradually. The sensitization to cat dander and dog dander showed a growing trend, and sensitization to Humulus japonicus, Candida, and cockroach decreased after 2005. Conclusion Over the past 40 years, the allergen sensitization in Korean children with allergic diseases has increased. These changes reflect lifestyle and environmental changes and influence allergic disease management approaches. Thus, changes in allergic sensitization should be monitored continuously. | - |
dc.description.statementOfResponsibility | open | - |
dc.publisher | Korean Academy of Pediatric Allergy and Respiratory Disease | - |
dc.relation.isPartOf | ALLERGY ASTHMA & RESPIRATORY DISEASE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | 1980–2019년 기간 동안 소아청소년 알레르기질환에서 항원 감작의 변화 | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학교실) | - |
dc.contributor.googleauthor | 정재화 | - |
dc.contributor.googleauthor | 김가은 | - |
dc.contributor.googleauthor | 박미르 | - |
dc.contributor.googleauthor | 김수연 | - |
dc.contributor.googleauthor | 김민정 | - |
dc.contributor.googleauthor | 이용주 | - |
dc.contributor.googleauthor | 김윤희 | - |
dc.contributor.googleauthor | 김경원 | - |
dc.contributor.googleauthor | 손명현 | - |
dc.identifier.doi | 10.4168/aard.2021.9.4.208 | - |
dc.contributor.localId | A00303 | - |
dc.contributor.localId | A00472 | - |
dc.contributor.localId | A04724 | - |
dc.contributor.localId | A00799 | - |
dc.contributor.localId | A05810 | - |
dc.contributor.localId | A01967 | - |
dc.contributor.localId | A02983 | - |
dc.contributor.localId | A06083 | - |
dc.relation.journalcode | J00065 | - |
dc.subject.keyword | Child | - |
dc.subject.keyword | Allergens | - |
dc.subject.keyword | Sensitization | - |
dc.subject.keyword | Change | - |
dc.contributor.alternativeName | Kim, Kyung Won | - |
dc.contributor.affiliatedAuthor | 김경원 | - |
dc.contributor.affiliatedAuthor | 김민정 | - |
dc.contributor.affiliatedAuthor | 김수연 | - |
dc.contributor.affiliatedAuthor | 김윤희 | - |
dc.contributor.affiliatedAuthor | 박미르 | - |
dc.contributor.affiliatedAuthor | 손명현 | - |
dc.contributor.affiliatedAuthor | 이용주 | - |
dc.contributor.affiliatedAuthor | 정재화 | - |
dc.citation.volume | 9 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 208 | - |
dc.citation.endPage | 215 | - |
dc.identifier.bibliographicCitation | ALLERGY ASTHMA & RESPIRATORY DISEASE, Vol.9(4) : 208-215, 2021-10 | - |
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