Cited 73 times in
Behçet syndrome
DC Field | Value | Language |
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dc.contributor.author | 천재희 | - |
dc.date.accessioned | 2022-09-14T01:33:07Z | - |
dc.date.available | 2022-09-14T01:33:07Z | - |
dc.date.issued | 2021-09 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/190509 | - |
dc.description.abstract | Behçet syndrome is a systemic vasculitis with an unknown aetiology affecting the small and large vessels of the venous and arterial systems. The presence of symptom clusters, regional differences in disease expression and similarities with, for example, Crohn's disease suggest that multiple pathological pathways are involved in Behçet syndrome. These disease features also make formulating disease criteria difficult. Genetic studies have identified HLA-B*51 as a genetic risk factor. However, the low prevalence of HLA-B*51 in many patients with bona fide disease, especially in non-endemic regions, suggests that other factors must also be operative in Behçet syndrome. Despite lacking a clear aetiological mechanism and definition, management of manifestations that include major vascular disease, eye disease and central nervous system involvement has improved with the help of new technology. Furthermore, even with our incomplete understanding of disease mechanisms, the prognoses of patients with Behçet syndrome, including those with eye disease, continue to improve. New treatment options and a better understanding of the underlying pathogenesis for various manifestations of this condition are required to further improve the management of the disease, which will improve patient quality of life. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Nature Publishing Group | - |
dc.relation.isPartOf | NATURE REVIEWS DISEASE PRIMERS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Behcet Syndrome* / complications | - |
dc.subject.MESH | Behcet Syndrome* / diagnosis | - |
dc.subject.MESH | Behcet Syndrome* / epidemiology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Quality of Life | - |
dc.subject.MESH | Risk Factors | - |
dc.title | Behçet syndrome | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Yusuf Yazici | - |
dc.contributor.googleauthor | Gulen Hatemi | - |
dc.contributor.googleauthor | Bahram Bodaghi | - |
dc.contributor.googleauthor | Jae Hee Cheon | - |
dc.contributor.googleauthor | Noburu Suzuki | - |
dc.contributor.googleauthor | Nicola Ambrose | - |
dc.contributor.googleauthor | Hasan Yazici | - |
dc.identifier.doi | 10.1038/s41572-021-00301-1 | - |
dc.contributor.localId | A04030 | - |
dc.relation.journalcode | J04290 | - |
dc.identifier.eissn | 2056-676X | - |
dc.identifier.pmid | 34531393 | - |
dc.identifier.url | https://www.nature.com/articles/s41572-021-00301-1 | - |
dc.contributor.alternativeName | Cheon, Jae Hee | - |
dc.contributor.affiliatedAuthor | 천재희 | - |
dc.citation.volume | 7 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 67 | - |
dc.identifier.bibliographicCitation | NATURE REVIEWS DISEASE PRIMERS, Vol.7(1) : 67, 2021-09 | - |
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