Cited 0 times in
Effect of ambulatory blood pressure monitoring guided antihypertensive treatment on renal progression in patients with chronic kidney disease: a randomized comparative study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 유태현 | - |
dc.date.accessioned | 2022-09-14T01:13:19Z | - |
dc.date.available | 2022-09-14T01:13:19Z | - |
dc.date.issued | 2021-02 | - |
dc.identifier.issn | 0263-6352 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/190349 | - |
dc.description.abstract | Objectives: Adequate blood pressure (BP) control is pivotal for managing chronic kidney disease (CKD). The optimal approach for monitoring BP to delay CKD progression is not yet clear. Methods: Patients with hypertension and CKD stage 3-4 were randomized into ambulatory blood pressure monitoring (ABPM) or office BP groups. All patients had ABPM at baseline and 18 months, and the ABPM group additionally underwent ABPM at 3 and 6 months. Each ABPM result was notified only for the ABPM group. The BP target was daytime ABP less than 135/85 mmHg for the ABPM group and office BP less than 140/90 mmHg for the office BP group. The primary outcome was decrease in estimated glomerular filtration rate (eGFR) during 18 months. Results: A total of 146 patients were randomized into the ABPM (n = 69) and office BP groups (n = 77). Although office BP was comparable in the two groups at baseline, daytime ABP was higher in the ABPM group (median 140 vs. 132 mmHg). Initial eGFR was 35.7 ± 12.5 ml/min per 1.73 m2 in the ABPM group and 34.6 ± 12.0 ml/min per 1.73 m2 in the office BP group. eGFR change was -5.5 [95% confidence interval (95% CI) -7.7 to -3.4] ml/min per 1.73 m2 in the ABPM group and -5.0 (95% CI -6.9 to -3.0) ml/min per 1.73 m2 in the office BP group (P = 0.704). Renal events occurred in 10 patients (15.6%) from the ABPM group and five (7.1%) from the office BP group (P = 0.120). Conclusion: The present study did not show a beneficial effect of ABPM for controlling hypertension in CKD compared with conventional office BP monitoring in terms of renal outcomes. Trial registration: ClinicalTrials.gov NCT02417571. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Lippincott Williams & Wilkins | - |
dc.relation.isPartOf | JOURNAL OF HYPERTENSION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Antihypertensive Agents / therapeutic use | - |
dc.subject.MESH | Blood Pressure | - |
dc.subject.MESH | Blood Pressure Monitoring, Ambulatory | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypertension* / complications | - |
dc.subject.MESH | Hypertension* / drug therapy | - |
dc.subject.MESH | Renal Insufficiency, Chronic* / complications | - |
dc.subject.MESH | Renal Insufficiency, Chronic* / drug therapy | - |
dc.title | Effect of ambulatory blood pressure monitoring guided antihypertensive treatment on renal progression in patients with chronic kidney disease: a randomized comparative study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Yunmi Kim | - |
dc.contributor.googleauthor | Jayoun Kim | - |
dc.contributor.googleauthor | Sung Woo Lee | - |
dc.contributor.googleauthor | Suah Sung | - |
dc.contributor.googleauthor | Tae-Hyun Yoo | - |
dc.contributor.googleauthor | Kyu-Beck Lee | - |
dc.contributor.googleauthor | Young-Hwan Hwang | - |
dc.contributor.googleauthor | Taehee Kim | - |
dc.contributor.googleauthor | Sun Woo Kang | - |
dc.contributor.googleauthor | Yeong Hoon Kim | - |
dc.contributor.googleauthor | Kook-Hwan Oh | - |
dc.identifier.doi | 10.1097/HJH.0000000000002624 | - |
dc.contributor.localId | A02526 | - |
dc.relation.journalcode | J01448 | - |
dc.identifier.eissn | 1473-5598 | - |
dc.identifier.pmid | 33031169 | - |
dc.identifier.url | https://journals.lww.com/jhypertension/Fulltext/2021/02000/Effect_of_ambulatory_blood_pressure_monitoring.19.aspx | - |
dc.contributor.alternativeName | Yoo, Tae Hyun | - |
dc.contributor.affiliatedAuthor | 유태현 | - |
dc.citation.volume | 39 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 325 | - |
dc.citation.endPage | 332 | - |
dc.identifier.bibliographicCitation | JOURNAL OF HYPERTENSION, Vol.39(2) : 325-332, 2021-02 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.