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ACE Inhibitors Versus ARBs in Patients With NSTEMI With Preserved LV Systolic Function Who Underwent PCI With New Generation Drug-Eluting Stents

DC Field Value Language
dc.contributor.author고영국-
dc.contributor.author김병극-
dc.contributor.author김중선-
dc.contributor.author안철민-
dc.contributor.author장양수-
dc.contributor.author최동훈-
dc.contributor.author홍명기-
dc.contributor.author홍성진-
dc.date.accessioned2022-09-06T06:38:04Z-
dc.date.available2022-09-06T06:38:04Z-
dc.date.issued2020-02-
dc.identifier.issn0003-3197-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/190241-
dc.description.abstractThe relative superiority of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) on long-term clinical outcomes in patients with non-ST-segment elevation myocardial infarction (NSTEMI) with preserved left ventricular systolic function in the era of new generation drug-eluting stents is not well established. A total of 6436 patients with NSTEMI (ACEIs group: n = 3965 vs ARBs group: n = 2471) were enrolled. The major clinical end point was the occurrences of major adverse cardiac events (MACEs), defined as all-cause death, recurrent myocardial infarction (re-MI), and any repeat revascularization. After propensity score matching analysis, the cumulative incidences of MACEs (hazard ratio, 1.334; 95% confidence interval, 1.045-1.703; P = .021), any repeat revascularization, and target vessel revascularization (TVR) in the ARB group were significantly higher than that in the ACEI group. However, the cumulative incidences of all-cause death, cardiac death, re-MI, target lesion revascularization, and non-TVR were similar between the 2 groups. Hence, although the mortality and re-MI reduction benefits were similar between the 2 groups, the ACEIs group showed more prominent ability to decrease the occurrences of MACEs, any repeat revascularization, and TVR compared to the ARBs group in these patients during a 2-year follow-up period.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherSage Publications-
dc.relation.isPartOfANGIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAged-
dc.subject.MESHAngiotensin Receptor Antagonists / therapeutic use*-
dc.subject.MESHAngiotensin-Converting Enzyme Inhibitors / therapeutic use*-
dc.subject.MESHDrug-Eluting Stents*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNon-ST Elevated Myocardial Infarction / surgery*-
dc.subject.MESHPercutaneous Coronary Intervention*-
dc.subject.MESHPostoperative Complications / epidemiology*-
dc.subject.MESHPostoperative Complications / prevention & control*-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHSystole / physiology-
dc.subject.MESHVentricular Function, Left / physiology-
dc.titleACE Inhibitors Versus ARBs in Patients With NSTEMI With Preserved LV Systolic Function Who Underwent PCI With New Generation Drug-Eluting Stents-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorYong Hoon Kim-
dc.contributor.googleauthorAe-Young Her-
dc.contributor.googleauthorMyung Ho Jeong-
dc.contributor.googleauthorByeong-Keuk Kim-
dc.contributor.googleauthorSung-Jin Hong-
dc.contributor.googleauthorSeunghwan Kim-
dc.contributor.googleauthorChul-Min Ahn-
dc.contributor.googleauthorJung-Sun Kim-
dc.contributor.googleauthorYoung-Guk Ko-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorMyeong-Ki Hong-
dc.contributor.googleauthorYangsoo Jang-
dc.identifier.doi10.1177/0003319719884187-
dc.contributor.localIdA00127-
dc.contributor.localIdA00493-
dc.contributor.localIdA00961-
dc.contributor.localIdA02269-
dc.contributor.localIdA03448-
dc.contributor.localIdA04053-
dc.contributor.localIdA04391-
dc.contributor.localIdA04403-
dc.relation.journalcodeJ00148-
dc.identifier.eissn1940-1574-
dc.identifier.pmid31694385-
dc.identifier.urlhttps://journals.sagepub.com/doi/10.1177/0003319719884187-
dc.subject.keywordnon-ST-segment elevation myocardial infarction-
dc.subject.keywordrenin-angiotensin system-
dc.subject.keywordoutcomes-
dc.contributor.alternativeNameKo, Young Guk-
dc.contributor.affiliatedAuthor고영국-
dc.contributor.affiliatedAuthor김병극-
dc.contributor.affiliatedAuthor김중선-
dc.contributor.affiliatedAuthor안철민-
dc.contributor.affiliatedAuthor장양수-
dc.contributor.affiliatedAuthor최동훈-
dc.contributor.affiliatedAuthor홍명기-
dc.contributor.affiliatedAuthor홍성진-
dc.citation.volume71-
dc.citation.number2-
dc.citation.startPage139-
dc.citation.endPage149-
dc.identifier.bibliographicCitationANGIOLOGY, Vol.71(2) : 139-149, 2020-02-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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