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Non-invasive ventilation for acute respiratory failure: pressure support ventilation vs. pressure-controlled ventilation
DC Field | Value | Language |
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dc.contributor.author | 조재화 | - |
dc.date.accessioned | 2022-09-06T06:02:44Z | - |
dc.date.available | 2022-09-06T06:02:44Z | - |
dc.date.issued | 2020-05 | - |
dc.identifier.issn | 2072-1439 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/190126 | - |
dc.description.abstract | Background: The best ventilator mode for patients receiving non-invasive ventilation (NIV) has not been clarified. This study compared the effectiveness of two pressure-targeted modes, i.e., pressure support ventilation (PSV) and pressure-controlled ventilation (PCV), in patients receiving NIV. Methods: This was a prospective multicentre observational study of NIV use for acute respiratory failure (ARF) in adult patients. We compared the two pressure-targeted modes in terms of NIV success and complication rates. Results: Among 176 patients receiving NIV, 88 patients were included in the study (PCV mode, n=29; PSV mode, n=59). The study population had a median age of 73.0 years and median body mass index of 20.8 kg/m(2). The applied inspiratory positive airway pressure (IPAP) was higher in patients with PCV than in those with PSV [18.0 cmH(2)O (15.0-20.5 cmH(2)O) vs. 15.0 cmH(2)O (12.0-17.0 cmH(2)O), respectively, P=0.001]. More patients with PCV received sedatives and experienced dry mouth than those with PSV; however, the incidences of large leaks were low in both groups (n=5 vs. n=2, respectively). With regard to NIV outcomes, 24 (27.2%) patients experienced NIV failure and 13 (14.8%) died in hospital. PSV mode was a significant factor for NIV success [odds ratio (OR), 2.303; 95% confidence interval (CI), 1.216 to 4.360] in multivariate analyses and this association remained significant in a 1:1 matched cohort (n=29 per group). Conclusions: In contrast to PCV mode, PSV mode was significantly associated with NIV success in the intensive care unit setting, particularly when large leaks were not a major concern. Nevertheless, further well-designed multicenter, protocol-driven randomized controlled trials are warranted. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Pioneer Bioscience Pub. Co. | - |
dc.relation.isPartOf | JOURNAL OF THORACIC DISEASE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Non-invasive ventilation for acute respiratory failure: pressure support ventilation vs. pressure-controlled ventilation | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Hyunseung Nam | - |
dc.contributor.googleauthor | Jae Hwa Cho | - |
dc.contributor.googleauthor | Tai Sun Park | - |
dc.contributor.googleauthor | Sei Won Kim | - |
dc.contributor.googleauthor | Hyung Koo Kang | - |
dc.contributor.googleauthor | Yoon Mi Shin | - |
dc.contributor.googleauthor | Jae Joon Hwang | - |
dc.contributor.googleauthor | Kwangha Lee | - |
dc.contributor.googleauthor | Jick Hwan Ha | - |
dc.contributor.googleauthor | Young Seok Lee | - |
dc.contributor.googleauthor | Youjin Chang | - |
dc.contributor.googleauthor | Sunghoon Park | - |
dc.identifier.doi | 10.21037/jtd.2020.03.27 | - |
dc.contributor.localId | A05674 | - |
dc.relation.journalcode | J01907 | - |
dc.identifier.eissn | 2077-6624 | - |
dc.identifier.pmid | 32642163 | - |
dc.subject.keyword | Non-invasive ventilation (NIV) | - |
dc.subject.keyword | acute respiratory failure (ARF) | - |
dc.subject.keyword | treatment outcome | - |
dc.contributor.alternativeName | Cho, Jaehwa | - |
dc.contributor.affiliatedAuthor | 조재화 | - |
dc.citation.volume | 12 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 2553 | - |
dc.citation.endPage | 2562 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THORACIC DISEASE, Vol.12(5) : 2553-2562, 2020-05 | - |
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