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The Plasma Atherogenic Index is an Independent Predictor of Arterial Stiffness in Healthy Koreans

Authors
 Ji Sun Nam  ;  Min Kyung Kim  ;  Kahui Park  ;  Arim Choi  ;  Shinae Kang  ;  Chul Woo Ahn  ;  Jong Suk Park 
Citation
 ANGIOLOGY, Vol.73(6) : 514-519, 2022-07 
Journal Title
ANGIOLOGY
ISSN
 0003-3197 
Issue Date
2022-07
MeSH
Adult ; Ankle Brachial Index ; Cardiovascular Diseases* ; Cholesterol, HDL ; Female ; Humans ; Male ; Pulse Wave Analysis ; Republic of Korea / epidemiology ; Risk Factors ; Vascular Stiffness*
Keywords
arterial stiffness ; atherogenic index of plasma ; atherosclerosis ; pulse wave velocity
Abstract
The plasma atherogenic index (AIP) has been suggested as a useful independent predictor of cardiovascular diseases (CVDs) in high CV risk patients. We investigated the association between AIP and arterial stiffness measured by brachial-ankle pulse wave velocity (baPWV) in healthy adults. A total of 3468 healthy subjects without any metabolic or CV diseases were enrolled. Anthropometric and CV risk factors were measured. The AIP was defined as the base 10 logarithm of the ratio of the concentration of triglycerides to high-density lipoprotein-cholesterol. Subjects were classified into AIP quartiles. There were gradual deteriorations in metabolic parameters and increase in baPWV across the increasing AIP quartiles. In a fully adjusted analysis, compared with Q1 (lowest quartile) group, the odds ratio (95% confidence interval) for increased baPWV was higher in Q2 1.51, Q3 1.64, and Q4 (highest quartile) 2.77 among men, and Q2 1.09, Q3 1.55, and Q4 1.83 among women (all P trend <0 .05). There was a strong association between AIP and baPWV, and a higher AIP was an independent predictor of increased arterial stiffness in healthy Korean men and women. The AIP may be a simple screening tool for subclinical atherosclerosis.
Full Text
https://journals.sagepub.com/doi/10.1177/00033197211054242?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
DOI
10.1177/00033197211054242
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Shin Ae(강신애) ORCID logo https://orcid.org/0000-0002-9719-4774
Nam, Ji Sun(남지선) ORCID logo https://orcid.org/0000-0001-8655-5258
Park, Kahui(박가희)
Park, Jong Suk(박종숙) ORCID logo https://orcid.org/0000-0002-5385-1373
Ahn, Chul Woo(안철우) ORCID logo https://orcid.org/0000-0003-3733-7486
Choi, Arim(최아림)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/189574
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