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PD-L1 expression and overall survival in Asian and western patients with gastric cancer

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dc.contributor.author김효송-
dc.contributor.author라선영-
dc.contributor.author정현철-
dc.date.accessioned2022-08-23T00:28:51Z-
dc.date.available2022-08-23T00:28:51Z-
dc.date.issued2022-07-
dc.identifier.issn1479-6694-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/189453-
dc.description.abstractAim: Data are limited on PD-L1 expression and its association with overall survival (OS) in gastric cancer (GC) patients receiving routine care in different regions. Materials & methods: In a retrospective study, PD-L1 expression was assayed using the 22C3 pharmDx on GC tumor samples collected between 2003 and 2017 at South Korean and US cancer centers. PD-L1 positivity was defined as combined positive score (CPS) ≥1. The relationship between PD-L1 and OS was analyzed. Results: Of 574 GC tumor samples, 67.4% were CPS ≥1 (68.7% in Korean and 65.7% in US patients). PD-L1 expression was not associated with OS (adjusted hazard ratio: 0.94; 95% CI: 0.75-1.17). Conclusion: PD-L1 prevalence and its association with OS was similar between South Korean and US GC patients.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherFuture Medicine Ltd.-
dc.relation.isPartOfFUTURE ONCOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHB7-H1 Antigen* / metabolism-
dc.subject.MESHBiomarkers, Tumor / metabolism-
dc.subject.MESHHumans-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHStomach Neoplasms* / pathology-
dc.titlePD-L1 expression and overall survival in Asian and western patients with gastric cancer-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorSun Young Rha-
dc.contributor.googleauthorGeoffrey Y Ku-
dc.contributor.googleauthorHyo Song Kim-
dc.contributor.googleauthorHyun Cheol Chung-
dc.contributor.googleauthorFatemeh Ghazanfari Amlashi-
dc.contributor.googleauthorDipen Maheshbhai Maru-
dc.contributor.googleauthorCarly A Fein-
dc.contributor.googleauthorLaura H Tang-
dc.contributor.googleauthorWei Zhou-
dc.contributor.googleauthorTing Wu-
dc.contributor.googleauthorSenaka A Peter-
dc.contributor.googleauthorDavid P Kelsen-
dc.contributor.googleauthorJaffer A Ajani-
dc.identifier.doi10.2217/fon-2022-0103-
dc.contributor.localIdA01202-
dc.contributor.localIdA01316-
dc.contributor.localIdA03773-
dc.relation.journalcodeJ00914-
dc.identifier.eissn1744-8301-
dc.identifier.pmid35616013-
dc.identifier.urlhttps://www.futuremedicine.com/doi/10.2217/fon-2022-0103?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed&-
dc.subject.keywordPD-L1-
dc.subject.keywordexpression-
dc.subject.keywordgastric cancer-
dc.subject.keywordoverall survival-
dc.subject.keywordprognosis-
dc.contributor.alternativeNameKim, Hyo Song-
dc.contributor.affiliatedAuthor김효송-
dc.contributor.affiliatedAuthor라선영-
dc.contributor.affiliatedAuthor정현철-
dc.citation.volume18-
dc.citation.number21-
dc.citation.startPage2623-
dc.citation.endPage2634-
dc.identifier.bibliographicCitationFUTURE ONCOLOGY, Vol.18(21) : 2623-2634, 2022-07-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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