Cited 5 times in
Vitamin D Deficiency and Neurologic Outcome After Sudden Cardiac Arrest
DC Field | Value | Language |
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dc.contributor.author | 위진 | - |
dc.contributor.author | 차정준 | - |
dc.date.accessioned | 2022-08-19T06:30:48Z | - |
dc.date.available | 2022-08-19T06:30:48Z | - |
dc.date.issued | 2019-12 | - |
dc.identifier.issn | 1073-2322 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/189238 | - |
dc.description.abstract | Background: Vitamin D deficiency is related to various cardiovascular diseases, including sudden cardiac arrest (SCA). This study investigated the association of vitamin D level with neurologic outcome and mortality after resuscitation from SCA. Patients and Methods: We enrolled patients who were successfully resuscitated from out-of-hospital cardiac arrest of presumed cardiac cause in Severance Cardiovascular Hospital as a prospective cohort registry. Baseline blood samples including pH, lactate, and vitamin D were obtained without fluid replacement just after hospital admission. Outcome was assessed by cerebral performance category (CPC) score at 1 month after SCA. Favorable outcome was defined as survival with CPC score of 1 or 2, whereas unfavorable one as death or survival with CPC scores of 3 through 5. Severe vitamin D deficiency was defined as 25(OH)D <10 ng/mL. Results: A total of 163 patients were included. Overall 96 (59%) patients had a favorable neurologic outcome, whereas 67 patients (41%) showed unfavorable outcome, including 37 (23%) mortality. Patients with unfavorable outcome were likely to be female and have initial non-shockable rhythm, longer arrest time, severe shock, diabetes, and baseline renal dysfunction. In multivariate analysis, severe vitamin D deficiency was one of the poor prognostic factors of both unfavorable neurologic outcome and mortality after SCA. Conclusions: Vitamin D deficiency is very prevalent and strongly associated with both unfavorable neurologic outcome and mortality in patients resuscitated from SCA. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Lippincott Williams & Wilkins | - |
dc.relation.isPartOf | SHOCK | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Death, Sudden, Cardiac* | - |
dc.subject.MESH | Disease-Free Survival | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Nervous System Diseases* / blood | - |
dc.subject.MESH | Nervous System Diseases* / etiology | - |
dc.subject.MESH | Nervous System Diseases* / mortality | - |
dc.subject.MESH | Sex Factors | - |
dc.subject.MESH | Survival Rate | - |
dc.subject.MESH | Vitamin D Deficiency* / blood | - |
dc.subject.MESH | Vitamin D Deficiency* / complications | - |
dc.subject.MESH | Vitamin D Deficiency* / mortality | - |
dc.title | Vitamin D Deficiency and Neurologic Outcome After Sudden Cardiac Arrest | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Jung-Joon Cha | - |
dc.contributor.googleauthor | Jin Wi | - |
dc.identifier.doi | 10.1097/SHK.0000000000001335 | - |
dc.contributor.localId | A02450 | - |
dc.contributor.localId | A04851 | - |
dc.relation.journalcode | J02658 | - |
dc.identifier.eissn | 1540-0514 | - |
dc.identifier.pmid | 31524672 | - |
dc.identifier.url | https://journals.lww.com/shockjournal/Fulltext/2019/12000/Vitamin_D_Deficiency_and_Neurologic_Outcome_After.17.aspx | - |
dc.subject.keyword | Cerebral performance category | - |
dc.subject.keyword | resuscitation | - |
dc.subject.keyword | sudden cardiac arrest | - |
dc.subject.keyword | vitamin D deficiency | - |
dc.contributor.alternativeName | Wi, Jin | - |
dc.contributor.affiliatedAuthor | 위진 | - |
dc.contributor.affiliatedAuthor | 차정준 | - |
dc.citation.volume | 52 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | E146 | - |
dc.citation.endPage | E152 | - |
dc.identifier.bibliographicCitation | SHOCK, Vol.52(6) : E146-E152, 2019-12 | - |
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