Cited 57 times in
The Effect of Nutrition Intervention with Oral Nutritional Supplements on Pancreatic and Bile Duct Cancer Patients Undergoing Chemotherapy
DC Field | Value | Language |
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dc.contributor.author | 박준성 | - |
dc.contributor.author | 이동기 | - |
dc.contributor.author | 이익재 | - |
dc.contributor.author | 정희철 | - |
dc.date.accessioned | 2022-08-19T06:28:48Z | - |
dc.date.available | 2022-08-19T06:28:48Z | - |
dc.date.issued | 2019-05 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/189208 | - |
dc.description.abstract | Chemotherapy may negatively affect nutritional status and quality of life (QOL) in pancreatic cancer patients. Our aim was to investigate the beneficial effects of oral nutrition supplements (ONS) on pancreatic and bile duct cancer patients undergoing chemotherapy. Among patients with progressive pancreatic and bile duct cancer receiving chemotherapy, the ONS group (n = 15) received two packs of ONS daily for 8 weeks while the non-ONS group (n = 19) did not. Anthropometric measures, dietary intake, nutritional status, and quality of life were assessed. ONS significantly increased daily intakes of energy, carbohydrates, proteins, and lipids at 8 weeks compared to the baseline. After 8 weeks, fat mass significantly increased in the ONS group. For patients in their first cycle of chemotherapy, body weight, fat-free mass, skeletal muscle mass, body cell mass, and fat mass increased in the ONS group but decreased in the non-ONS group. Fat mass increased in second or higher cycle only in the ONS group. Patient-generated subjective global assessments (PG-SGA) and fatigue scores in the Quality of Life Questionnaire Core 30 (QLQ-C30) improved in the ONS group. ONS might improve nutritional status by increasing fat mass and/or maintaining the body composition of pancreatic and bile duct cancer patients with chemotherapy, especially those in the first cycle, and alleviate fatigue symptoms. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | MDPI Publishing | - |
dc.relation.isPartOf | NUTRIENTS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Bile Duct Neoplasms / drug therapy | - |
dc.subject.MESH | Bile Duct Neoplasms / therapy* | - |
dc.subject.MESH | Body Composition | - |
dc.subject.MESH | Body Weight | - |
dc.subject.MESH | Diet | - |
dc.subject.MESH | Dietary Supplements* | - |
dc.subject.MESH | Energy Intake | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Nutrition Therapy / methods* | - |
dc.subject.MESH | Nutritional Status | - |
dc.subject.MESH | Pancreatic Neoplasms / drug therapy | - |
dc.subject.MESH | Pancreatic Neoplasms / therapy* | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Quality of Life | - |
dc.subject.MESH | Surveys and Questionnaires | - |
dc.title | The Effect of Nutrition Intervention with Oral Nutritional Supplements on Pancreatic and Bile Duct Cancer Patients Undergoing Chemotherapy | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.googleauthor | Seong Hyeon Kim | - |
dc.contributor.googleauthor | Song Mi Lee | - |
dc.contributor.googleauthor | Hei Cheul Jeung | - |
dc.contributor.googleauthor | Ik Jae Lee | - |
dc.contributor.googleauthor | Joon Seong Park | - |
dc.contributor.googleauthor | Mina Song | - |
dc.contributor.googleauthor | Dong Ki Lee | - |
dc.contributor.googleauthor | Seung-Min Lee | - |
dc.identifier.doi | 10.3390/nu11051145 | - |
dc.contributor.localId | A01672 | - |
dc.contributor.localId | A02723 | - |
dc.contributor.localId | A03055 | - |
dc.contributor.localId | A03794 | - |
dc.relation.journalcode | J02396 | - |
dc.identifier.eissn | 2072-6643 | - |
dc.identifier.pmid | 31121926 | - |
dc.subject.keyword | pancreatic and bile duct cancer | - |
dc.subject.keyword | chemotherapy | - |
dc.subject.keyword | oral nutritional supplement (ONS) | - |
dc.subject.keyword | nutritional status | - |
dc.subject.keyword | patient-generated subjective global assessments | - |
dc.subject.keyword | Quality of Life Questionnaire Core 30 | - |
dc.contributor.alternativeName | Park, Joon Seong | - |
dc.contributor.affiliatedAuthor | 박준성 | - |
dc.contributor.affiliatedAuthor | 이동기 | - |
dc.contributor.affiliatedAuthor | 이익재 | - |
dc.contributor.affiliatedAuthor | 정희철 | - |
dc.citation.volume | 11 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 1145 | - |
dc.identifier.bibliographicCitation | NUTRIENTS, Vol.11(5) : 1145, 2019-05 | - |
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