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Perforation in Submucous Cleft Palate Due to Methotrexate-Induced Mucositis in a Patient With Rheumatoid Arthritis
DC Field | Value | Language |
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dc.date.accessioned | 2022-08-16T01:32:36Z | - |
dc.date.available | 2022-08-16T01:32:36Z | - |
dc.date.issued | 2018-05 | - |
dc.identifier.issn | 1049-2275 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/188931 | - |
dc.description.abstract | Spontaneous palatal perforation can be rarely developed by several causes, such as tumor, trauma, and infection. This article reports a patient with large mid-palatal perforation after suffering from severe oral mucositis, which occurred about a month after taking methotrexate (MTX) for rheumatoid arthritis. Through computed tomography and clinical examination, this patient was diagnosed with perforation in unrecognized submucous cleft palate (SMCP) due to drug-induced mucositis. After MTX discontinuation, the oral mucositis was almost healed completely in a month, and the hole was successfully closed by palatoplasty. The author can see that the palatal perforation can occur by oral complication of MTX in SMCP patient. It is an important awareness to dentists as the use of MTX continues to increase for antirheumatic therapy. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Lippincott Williams & Wilkins | - |
dc.relation.isPartOf | JOURNAL OF CRANIOFACIAL SURGERY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Antirheumatic Agents / adverse effects* | - |
dc.subject.MESH | Arthritis, Rheumatoid / drug therapy* | - |
dc.subject.MESH | Cleft Palate / diagnostic imaging | - |
dc.subject.MESH | Cleft Palate / pathology* | - |
dc.subject.MESH | Cleft Palate / surgery | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Methotrexate / adverse effects* | - |
dc.subject.MESH | Mouth Mucosa* / diagnostic imaging | - |
dc.subject.MESH | Mucositis / chemically induced* | - |
dc.subject.MESH | Mucositis / complications* | - |
dc.subject.MESH | Mucositis / diagnostic imaging | - |
dc.subject.MESH | Rupture, Spontaneous / diagnostic imaging | - |
dc.subject.MESH | Tomography, X-Ray Computed | - |
dc.title | Perforation in Submucous Cleft Palate Due to Methotrexate-Induced Mucositis in a Patient With Rheumatoid Arthritis | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Oral and Maxillofacial Surgery (구강악안면외과학교실) | - |
dc.contributor.googleauthor | Jung Woo Nam | - |
dc.identifier.doi | 10.1097/SCS.0000000000004437 | - |
dc.relation.journalcode | J01356 | - |
dc.identifier.eissn | 1536-3732 | - |
dc.identifier.pmid | 29481520 | - |
dc.identifier.url | https://journals.lww.com/jcraniofacialsurgery/Fulltext/2018/05000/Perforation_in_Submucous_Cleft_Palate_Due_to.56.aspx | - |
dc.citation.volume | 29 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 772 | - |
dc.citation.endPage | 773 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CRANIOFACIAL SURGERY, Vol.29(3) : 772-773, 2018-05 | - |
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