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Gold(I)-Catalyzed Intramolecular Hydrothiophenylation ofN-Thiophen-3-yl Alkynylamides for Accessing Thieno[3,2-b]pyridine-5(4H)-ones: Development of F-Actin Specific Fluorescent Probes

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dc.contributor.authorSung, Dan-Bi-
dc.contributor.authorHan, Janghee-
dc.contributor.authorKim, Yong-Keon-
dc.contributor.authorMun, Bo Hyun-
dc.contributor.authorPark, Sol-
dc.contributor.authorKim, Hyun Seok-
dc.contributor.authorLee, Jong Seok-
dc.date.accessioned2022-07-08T03:21:13Z-
dc.date.available2022-07-08T03:21:13Z-
dc.date.created2022-07-27-
dc.date.issued2022-04-
dc.identifier.issn0022-3263-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/188804-
dc.description.abstractHerein, we describe an original synthetic methodfor a series offluorescent thieno[3,2-b]pyridine-5(4H)-onederivatives prepared via the gold(I)-catalyzed 6-endo-dig intra-molecular hydrothiophenylation process involvingN-thiophen-3-ylalkynylamides. The brightness was improved; emission could betuned, and larger Stokes shifts were recorded. We also designedand synthesized the phalloidin-basedfluorescent chemical probesKF-P1andKF-P2to realizefluorescent F-actin imaging.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherAmerican Chemical Society-
dc.relation.isPartOfJournal of Organic Chemistry-
dc.relation.isPartOfJOURNAL OF ORGANIC CHEMISTRY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleGold(I)-Catalyzed Intramolecular Hydrothiophenylation ofN-Thiophen-3-yl Alkynylamides for Accessing Thieno[3,2-b]pyridine-5(4H)-ones: Development of F-Actin Specific Fluorescent Probes-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentBioMedical Science Institute (의생명과학부)-
dc.contributor.googleauthorSung, Dan-Bi-
dc.contributor.googleauthorHan, Janghee-
dc.contributor.googleauthorKim, Yong-Keon-
dc.contributor.googleauthorMun, Bo Hyun-
dc.contributor.googleauthorPark, Sol-
dc.contributor.googleauthorKim, Hyun Seok-
dc.contributor.googleauthorLee, Jong Seok-
dc.identifier.doi10.1021/acs.joc.1c02923-
dc.relation.journalcodeJ03666-
dc.identifier.eissn1520-6904-
dc.contributor.alternativeNameKim, Hyun Seok-
dc.contributor.affiliatedAuthorHan, Janghee-
dc.contributor.affiliatedAuthorKim, Yong-Keon-
dc.contributor.affiliatedAuthorKim, Hyun Seok-
dc.identifier.scopusid2-s2.0-85125121161-
dc.identifier.wosid000784116400043-
dc.citation.volume87-
dc.citation.number7-
dc.citation.startPage4936-
dc.citation.endPage4950-
dc.identifier.bibliographicCitationJournal of Organic Chemistry, Vol.87(7) : 4936-4950, 2022-04-
dc.identifier.rimsid75109-
dc.type.rimsART-
dc.description.journalClass1-
dc.description.journalClass1-
dc.subject.keywordPlusC-H BONDS-
dc.subject.keywordPlusHYDROARYLATION-
dc.subject.keywordPlusFLUOROPHORES-
dc.subject.keywordPlusDESIGN-
dc.subject.keywordPlusSCAFFOLDS-
dc.subject.keywordPlusCOUMARINS-
dc.subject.keywordPlusDISCOVERY-
dc.subject.keywordPlusALKYNES-
dc.subject.keywordPlusENTRY-
dc.type.docTypeArticle-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.relation.journalResearchAreaChemistry-
Appears in Collections:
1. College of Medicine (의과대학) > BioMedical Science Institute (의생명과학부) > 1. Journal Papers
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