Cited 0 times in
Heart-Rate-Corrected QT Interval Response to Ramosetron during Robot-Assisted Laparoscopic Prostatectomy: A Randomized Trial
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김소연 | - |
dc.contributor.author | 김승현 | - |
dc.contributor.author | 이보라 | - |
dc.contributor.author | 최승호 | - |
dc.date.accessioned | 2022-07-08T03:14:29Z | - |
dc.date.available | 2022-07-08T03:14:29Z | - |
dc.date.issued | 2022-05 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/188736 | - |
dc.description.abstract | Ramosetron, often used to prevent postoperative nausea and vomiting, might cause heart-rate-corrected (QTc) interval prolongation, as might robot-assisted laparoscopic prostatectomy (RALP), which requires a steep Trendelenburg position and CO2 pneumoperitoneum. This study aimed to determine how ramosetron administration affects the QTc interval in patients treated with RALP. Fifty-six subjects were randomly assigned to ramosetron (n = 28) or control (n = 28) groups. The ramosetron group received 0.3 mg of ramosetron after anesthetic induction, whereas the control group received normal saline. The QTc interval was measured before and after induction; after 5, 30, and 60 min of being placed in the Trendelenburg position; immediately after being returned to a supine position; and at the end of surgery. Linear mixed models were used to compare QT intervals between groups. QTc intervals did not differ significantly between groups over time (Pgroup×time = 0.111). However, they increased significantly in both groups after placement in the Trendelenburg position compared with before induction (Ptime < 0.001). This increase in QTc continued until the end of surgery in both groups. Based on these findings, ramosetron can be safely administered for the prevention of postoperative nausea and vomiting among patients undergoing RALP. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | JOURNAL OF PERSONALIZED MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Heart-Rate-Corrected QT Interval Response to Ramosetron during Robot-Assisted Laparoscopic Prostatectomy: A Randomized Trial | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) | - |
dc.contributor.googleauthor | Bora Lee | - |
dc.contributor.googleauthor | So Yeon Kim | - |
dc.contributor.googleauthor | Seung Hyun Kim | - |
dc.contributor.googleauthor | Hyukjin Yang | - |
dc.contributor.googleauthor | Jeong Hyun Jin | - |
dc.contributor.googleauthor | Seung Ho Choi | - |
dc.identifier.doi | 10.3390/jpm12050811 | - |
dc.contributor.localId | A00616 | - |
dc.contributor.localId | A05098 | - |
dc.contributor.localId | A02803 | - |
dc.contributor.localId | A04101 | - |
dc.relation.journalcode | J04078 | - |
dc.identifier.eissn | 2075-4426 | - |
dc.identifier.pmid | 35629233 | - |
dc.subject.keyword | QTc prolongation | - |
dc.subject.keyword | Trendelenburg | - |
dc.subject.keyword | ramosetron | - |
dc.subject.keyword | robot-assisted laparoscopic radical prostatectomy | - |
dc.contributor.alternativeName | Kim, So Yeon | - |
dc.contributor.affiliatedAuthor | 김소연 | - |
dc.contributor.affiliatedAuthor | 김승현 | - |
dc.contributor.affiliatedAuthor | 이보라 | - |
dc.contributor.affiliatedAuthor | 최승호 | - |
dc.citation.volume | 12 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 811 | - |
dc.identifier.bibliographicCitation | JOURNAL OF PERSONALIZED MEDICINE, Vol.12(5) : 811, 2022-05 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.