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Randomized controlled clinical trial comparing guided bone regeneration of peri-implant defects with soft-type block versus particulate bone substitutes: Six-month results of hard-tissue changes

Authors
 Goran I Benic  ;  Stefan P Bienz  ;  Young Woo Song  ;  Jae-Kook Cha  ;  Christoph H F Hämmerle  ;  Ui-Won Jung  ;  Ronald E Jung 
Citation
 JOURNAL OF CLINICAL PERIODONTOLOGY, Vol.49(5) : 480-495, 2022-05 
Journal Title
JOURNAL OF CLINICAL PERIODONTOLOGY
ISSN
 0303-6979 
Issue Date
2022-05
MeSH
Alveolar Ridge Augmentation* / methods ; Bone Regeneration ; Bone Substitutes* / therapeutic use ; Collagen / therapeutic use ; Dental Implantation, Endosseous / methods ; Dental Implants* ; Guided Tissue Regeneration, Periodontal / methods ; Humans ; Membranes, Artificial ; Minerals / therapeutic use
Keywords
CBCT ; alveolar ridge augmentation ; dental implants ; guided bone regeneration ; randomized controlled trial
Abstract
Aim: To test whether soft-type block bone substitute used for guided bone regeneration (GBR) of peri-implant defects leads to a different dimension of the augmented hard tissue than particulate bone substitute.

Materials and methods: In 40 patients, 40 two-piece dental implants were placed >2 months after tooth extraction. Following random allocation, 20 peri-implant bone dehiscences were grafted with a soft-type block made of synthetic biphasic calcium phosphate (BCP) + collagen and 20 bone dehiscences with particulate BCP. All the sites were covered with a collagen membrane stabilized with titanium pins. Immediately after wound closure and after 6 months, the horizontal dimension (HD) of the augmented hard tissue was measured at the level of implant shoulder using cone beam computed tomography. During re-entry at 6 months, the defect fill was clinically assessed.

Results: At 6 months, the median HD measured 1.15 mm (mean: 1.31 mm) in the soft-block group and 0.93 mm (mean: 1.05 mm) in the particulate group (p = .6). At 6 months, 7.1% of contained defects and 61.9% of non-contained defects showed an incomplete vertical defect fill.

Conclusions: Soft-type block of BCP + collagen used for GBR of peri-implant defects did not differ from particulate BCP regarding the dimension of the augmented hard tissue after 6 months of healing.
Full Text
https://onlinelibrary.wiley.com/doi/10.1111/jcpe.13606
DOI
10.1111/jcpe.13606
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers
Yonsei Authors
Song, Young Woo(송영우) ORCID logo https://orcid.org/0000-0003-1835-5646
Jung, Ui Won(정의원) ORCID logo https://orcid.org/0000-0001-6371-4172
Cha, Jae Kook(차재국) ORCID logo https://orcid.org/0000-0001-6817-9834
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/188659
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