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Safety and Efficacy of Contemporary Drug-Eluting Stents in Patients With ST-Segment Elevation Myocardial Infarction and a High Ischemic Risk

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dc.contributor.author김병극-
dc.contributor.author김용철-
dc.contributor.author이오현-
dc.contributor.author조덕규-
dc.contributor.author최동훈-
dc.contributor.author홍명기-
dc.contributor.author손낙훈-
dc.contributor.author김중선-
dc.date.accessioned2022-07-08T03:05:03Z-
dc.date.available2022-07-08T03:05:03Z-
dc.date.issued2022-05-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/188654-
dc.description.abstractBackground: In patients with ST-elevation myocardial infarction (STEMI) with a high risk of ischemic events, the safety and efficacy of drug-eluting stent (DES) are unclear. Methods: Based on the nationwide, multicenter, prospective registry, we selected 1,592 patients who underwent primary percutaneous coronary intervention (PCI) with everolimus-(EES) and zotarolimus-eluting stent (ZES) for STEMI with a high risk of an ischemic event. The occurrence of target lesion failure (TLF) for 3 years, defined as the composite of cardiac death, target vessel myocardial infarction (TV-MI), and ischemia-driven target lesion revascularization (ID-TLR), was evaluated. Results: The prevalence of high ischemic risk features was observed in 43.4% (2,744/6,325) of overall patients with STEMI. Among them, a total of 1,078 and 514 patients were treated with EES and ZES, respectively. At 3 years, the risk of TLF was not significantly different between the two groups (p = 0.93). In addition, the incidence of cardiac death, TV-MI, ID-TLR, and definite/probable stent thrombosis (ST) were also not different between the two groups. Moreover, elderly patients (age > 75 years) and PCI for the left main disease were identified as independent predictors of TLF. Conclusion: Implantation of EES or ZES provided comparable clinical outcomes in STEMI patients and high ischemic risks.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherFrontiers Media S.A.-
dc.relation.isPartOfFRONTIERS IN CARDIOVASCULAR MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleSafety and Efficacy of Contemporary Drug-Eluting Stents in Patients With ST-Segment Elevation Myocardial Infarction and a High Ischemic Risk-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorOh-Hyun Lee-
dc.contributor.googleauthorYongcheol Kim-
dc.contributor.googleauthorNak-Hoon Son-
dc.contributor.googleauthorDeok-Kyu Cho-
dc.contributor.googleauthorJung-Sun Kim-
dc.contributor.googleauthorByeong-Keuk Kim-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorMyeong-Ki Hong-
dc.contributor.googleauthorMyung Ho Jeong-
dc.contributor.googleauthorYangsoo Jang-
dc.identifier.doi10.3389/fcvm.2022.880351-
dc.contributor.localIdA00493-
dc.contributor.localIdA05886-
dc.contributor.localIdA05164-
dc.contributor.localIdA03813-
dc.contributor.localIdA04053-
dc.contributor.localIdA04391-
dc.relation.journalcodeJ04002-
dc.identifier.eissn2297-055X-
dc.identifier.pmid35677690-
dc.subject.keywordST-segment elevation myocardial infarction-
dc.subject.keyworddrug-eluting stent-
dc.subject.keywordhigh risk factor-
dc.subject.keywordpercutaneous coronary intervention (PCI)-
dc.subject.keywordtarget lesion failure-
dc.contributor.alternativeNameKim, Byeong Keuk-
dc.contributor.affiliatedAuthor김병극-
dc.contributor.affiliatedAuthor김용철-
dc.contributor.affiliatedAuthor이오현-
dc.contributor.affiliatedAuthor조덕규-
dc.contributor.affiliatedAuthor최동훈-
dc.contributor.affiliatedAuthor홍명기-
dc.citation.volume9-
dc.citation.startPage880351-
dc.identifier.bibliographicCitationFRONTIERS IN CARDIOVASCULAR MEDICINE, Vol.9 : 880351, 2022-05-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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