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Cited 11 times in

Increasing Fusobacterium infections with Fusobacterium varium, an emerging pathogen

DC Field Value Language
dc.contributor.author구남수-
dc.contributor.author김정호-
dc.contributor.author김진남-
dc.contributor.author백예지-
dc.contributor.author안진영-
dc.contributor.author염준섭-
dc.contributor.author이기현-
dc.contributor.author이세주-
dc.contributor.author이은화-
dc.contributor.author정수진-
dc.contributor.author최준용-
dc.date.accessioned2022-05-09T17:19:02Z-
dc.date.available2022-05-09T17:19:02Z-
dc.date.issued2022-04-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/188506-
dc.description.abstractInfections caused by Fusobacterium species are rare; however serious infections with complications or mortality may occur occasionally. We conducted a retrospective study to investigate the clinical features of patients with Fusobacterium infections and the differences between infections caused by the species F. necrophorum, F. nucleatum, and F. varium. Additionally, we attempted to identify risk factors for Fusobacterium-associated mortality. This study included all patients at a large tertiary care teaching hospital in South Korea with Fusobacterium infections from January 2006 to April 2021. Demographic, clinical, laboratory, and outcome data were analyzed. Multiple logistic regression analysis was performed to assess the risk factors for in-hospital mortality associated with F. nucleatum and F. varium infections. We identified 272 patients with Fusobacterium infections during the study period. The number of Fusobacterium cases has increased recently, with F. varium infections markedly increasing since 2016 and causing a significant proportion of infections. Patients with F. varium infections were older and had a higher proportion of nosocomial infections than the other groups. The F. nucleatum and F. varium groups showed higher in-hospital mortality than the F. necrophorum group. Through logistic regression analysis, APACHE II score and serum albumin level were considered risk factors for in-hospital mortality. APACHE II score was positively correlated with age, red cell distribution width, and serum blood urea nitrogen, and negatively correlated with serum albumin level. Infections caused by Fusobacterium species are increasing. F. varium causes a significant proportion of severe infections.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherPublic Library of Science-
dc.relation.isPartOfPLOS ONE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHFusobacterium Infections* / complications-
dc.subject.MESHFusobacterium Infections* / microbiology-
dc.subject.MESHFusobacterium*-
dc.subject.MESHHumans-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHSerum Albumin-
dc.titleIncreasing Fusobacterium infections with Fusobacterium varium, an emerging pathogen-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorSe Ju Lee-
dc.contributor.googleauthorYae Jee Baek-
dc.contributor.googleauthorJin Nam Kim-
dc.contributor.googleauthorKi Hyun Lee-
dc.contributor.googleauthorEun Hwa Lee-
dc.contributor.googleauthorJoon Sup Yeom-
dc.contributor.googleauthorJun Yong Choi-
dc.contributor.googleauthorNam Su Ku-
dc.contributor.googleauthorJin Young Ahn-
dc.contributor.googleauthorJung Ho Kim-
dc.contributor.googleauthorSu Jin Jeong-
dc.identifier.doi10.1371/journal.pone.0266610-
dc.contributor.localIdA00189-
dc.contributor.localIdA00902-
dc.contributor.localIdA05112-
dc.contributor.localIdA05921-
dc.contributor.localIdA02267-
dc.contributor.localIdA02353-
dc.contributor.localIdA06174-
dc.contributor.localIdA05162-
dc.contributor.localIdA06176-
dc.contributor.localIdA03638-
dc.contributor.localIdA04191-
dc.relation.journalcodeJ02540-
dc.identifier.eissn1932-6203-
dc.identifier.pmid35421136-
dc.contributor.alternativeNameKu, Nam Su-
dc.contributor.affiliatedAuthor구남수-
dc.contributor.affiliatedAuthor김정호-
dc.contributor.affiliatedAuthor김진남-
dc.contributor.affiliatedAuthor백예지-
dc.contributor.affiliatedAuthor안진영-
dc.contributor.affiliatedAuthor염준섭-
dc.contributor.affiliatedAuthor이기현-
dc.contributor.affiliatedAuthor이세주-
dc.contributor.affiliatedAuthor이은화-
dc.contributor.affiliatedAuthor정수진-
dc.contributor.affiliatedAuthor최준용-
dc.citation.volume17-
dc.citation.number4-
dc.citation.startPagee0266610-
dc.identifier.bibliographicCitationPLOS ONE, Vol.17(4) : e0266610, 2022-04-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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