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Cited 2 times in

Ischemic Stroke in Non-Gender-Related CHA 2 DS 2-VA Score 0~1 Is Associated With H 2 FPEF Score Among the Patients With Atrial Fibrillation

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dc.contributor.author김영대-
dc.contributor.author김태훈-
dc.contributor.author남효석-
dc.contributor.author박희남-
dc.contributor.author엄재선-
dc.contributor.author유희태-
dc.contributor.author이문형-
dc.contributor.author정보영-
dc.contributor.author허지회-
dc.date.accessioned2022-05-09T17:02:57Z-
dc.date.available2022-05-09T17:02:57Z-
dc.date.issued2022-02-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/188353-
dc.description.abstractBackground: Ischemic strokes (ISs) can appear even in non-gender-related CHA2DS2-VA scores 0~1 patients with atrial fibrillation (AF). We explored the determinants associated with IS development among the patients with non-gender-related CHA2DS2-VA score 0~1 AF. Methods and results: In this single-center retrospective registry data for AF catheter ablation (AFCA), we included 1,353 patients with AF (24.7% female, median age 56 years, and paroxysmal AF 72.6%) who had non-gender-related CHA2DS2-VA score 0~1, normal left ventricular (LV) systolic function, and available H2FPEF score. Among those patients, 113 experienced IS despite a non-gender-related CHA2DS2-VA score of 0~1. All included patients underwent AFCA, and we evaluated the associated factors with IS in non-gender-related CHA2DS2-VA score 0~1 AF. Patients with ISs in this study had a lower estimated glomerular filtration rate (eGFR) (p < 0.001) and LV ejection fraction (LVEF; p = 0.017), larger LA diameter (p < 0.001), reduced LA appendage peak velocity (p < 0.001), and a higher baseline H2FPEF score (p = 0.018) relative to those without ISs. Age [odds ratio (OR) 1.11 (1.07-1.17), p < 0.001, Model 1] and H2FPEF score as continuous [OR 1.31 (1.03-1.67), p = 0.028, Model 2] variable were independently associated with ISs by multivariate analysis. Moreover, the eGFR was independently associated with IS at low CHA2DS2-VA scores in both Models 1 and 2. AF recurrence was significantly higher in patients with IS (log-rank p < 0.001) but not in those with high H2FPEF scores (log-rank p = 0.079), respectively. Conclusions: Among the patients with normal LVEF and non-gender-related CHA2DS2-VA score 0~1 AF, the high H2FPEF score, and increasing age were independently associated with IS development (ClinicalTrials.gov Identifier: NCT02138695).-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherFrontiers Media S.A.-
dc.relation.isPartOfFRONTIERS IN CARDIOVASCULAR MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleIschemic Stroke in Non-Gender-Related CHA 2 DS 2-VA Score 0~1 Is Associated With H 2 FPEF Score Among the Patients With Atrial Fibrillation-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Neurology (신경과학교실)-
dc.contributor.googleauthorMin Kim-
dc.contributor.googleauthorHee Tae Yu-
dc.contributor.googleauthorTae-Hoon Kim-
dc.contributor.googleauthorDae-In Lee-
dc.contributor.googleauthorJae-Sun Uhm-
dc.contributor.googleauthorYoung Dae Kim-
dc.contributor.googleauthorHyo Suk Nam-
dc.contributor.googleauthorBoyoung Joung-
dc.contributor.googleauthorMoon-Hyoung Lee-
dc.contributor.googleauthorJi Hoe Heo-
dc.contributor.googleauthorHui-Nam Pak-
dc.identifier.doi10.3389/fcvm.2021.791112-
dc.contributor.localIdA00702-
dc.contributor.localIdA01085-
dc.contributor.localIdA01273-
dc.contributor.localIdA01776-
dc.contributor.localIdA02337-
dc.contributor.localIdA02535-
dc.contributor.localIdA02766-
dc.contributor.localIdA03609-
dc.contributor.localIdA04369-
dc.relation.journalcodeJ04002-
dc.identifier.eissn2297-055X-
dc.identifier.pmid35211517-
dc.subject.keywordCHA2DS2-VA score-
dc.subject.keywordH2FPEF score-
dc.subject.keywordatrial fibrillation-
dc.subject.keywordatrial myopathy-
dc.subject.keywordstroke-
dc.contributor.alternativeNameKim, Young Dae-
dc.contributor.affiliatedAuthor김영대-
dc.contributor.affiliatedAuthor김태훈-
dc.contributor.affiliatedAuthor남효석-
dc.contributor.affiliatedAuthor박희남-
dc.contributor.affiliatedAuthor엄재선-
dc.contributor.affiliatedAuthor유희태-
dc.contributor.affiliatedAuthor이문형-
dc.contributor.affiliatedAuthor정보영-
dc.contributor.affiliatedAuthor허지회-
dc.citation.volume8-
dc.citation.startPage791112-
dc.identifier.bibliographicCitationFRONTIERS IN CARDIOVASCULAR MEDICINE, Vol.8 : 791112, 2022-02-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers

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