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Nevus Comedonicus Syndrome Associated with Psychiatric Disorder

Authors
 Ha Young Woo  ;  Sang Kyum Kim 
Citation
 DIAGNOSTICS, Vol.12(2) : 383, 2022-02 
Journal Title
DIAGNOSTICS
Issue Date
2022-02
Keywords
attention-deficit hyperactivity disorder ; epidermal nevus syndrome ; nevus comedonicus ; nevus comedonicus syndrome
Abstract
Nevus comedonicus (NC) is a rare hamartoma of the pilosebaceous unit origin. The association with extracutaneous abnormalities defines NC syndrome (NCS). Fewer than 50 cases of NCS have been reported in the English literature. A 31-year-old woman presented with grouped and linear comedonal papules present from birth and located on the left buttock along Blaschko's lines. She had a history of pediatric mood disorder combined with attention-deficit hyperactivity disorder (ADHD) from 5 years of age and was recently diagnosed with sinus bradycardia. Her skin lesion was surgically removed and microscopic findings revealed the aggregation of dilated follicular infundibula filled with prominent laminated keratin plugs, a characteristic finding of NC. This is the first report presenting NCS associated with mood disorder and ADHD. Psychiatric symptoms may represent systemic manifestation of NCS.
Files in This Item:
T202200832.pdf Download
DOI
10.3390/diagnostics12020383
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sang Kyum(김상겸) ORCID logo https://orcid.org/0000-0003-0768-9923
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/188307
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