Cited 3 times in
Long-Term Outcomes and Prognostic Factors of Superficial Esophageal Cancer in Patients Aged ≥ 65 Years
DC Field | Value | Language |
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dc.contributor.author | 박준철 | - |
dc.contributor.author | 신성관 | - |
dc.contributor.author | 이상길 | - |
dc.contributor.author | 이용찬 | - |
dc.contributor.author | 장진원 | - |
dc.contributor.author | 정다현 | - |
dc.contributor.author | 허철웅 | - |
dc.date.accessioned | 2022-05-09T16:55:31Z | - |
dc.date.available | 2022-05-09T16:55:31Z | - |
dc.date.issued | 2022-01 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/188283 | - |
dc.description.abstract | Background: The number of elderly patients with superficial esophageal cancer (SEC) is increasing. We aimed to evaluate the clinical outcomes and prognostic factors of overall survival (OS) in elderly patients undergoing endoscopic submucosal dissection (ESD) or surgical resection for SEC. Methods: Between January 2001 and May 2020, 290 patients aged ≥65 years who underwent ESD or surgical resection for SEC were evaluated. Their clinical outcomes and prognosis were assessed, and independent risk factors for OS were identified. Results: The mean patient age (269 men and 21 women) was 70.9 years (range 65-90 years). En bloc, R0, and curative resections were achieved in 94.5%, 90.0%, and 73.4% of the patients, respectively. During the follow-up [mean: 54.6 months (range: 1-210 months)], 79 patients died. The 3-, 5-, and 10-year OS rates were 82.5, 73.1, and 59.7%, respectively. In multivariate analysis, cancer history of the other organs, American Society of Anesthesiologists performance status, and presence of lymphovascular involvement (hazard ratio = 1.852, 1.656, and 1.943, respectively; all P < 0.05) were independent risk factors for poor OS. The high-risk group (≥2 risk factors) showed a significantly lower OS than the low-risk group (≤ 1 risk factor) (P < 0.001). Conclusions: The three risk factors could be useful in predicting the long-term prognosis of elderly patients with SEC. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Frontiers Media S.A. | - |
dc.relation.isPartOf | FRONTIERS IN MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Long-Term Outcomes and Prognostic Factors of Superficial Esophageal Cancer in Patients Aged ≥ 65 Years | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Jin Won Chang | - |
dc.contributor.googleauthor | Da Hyun Jung | - |
dc.contributor.googleauthor | Cheal Wung Huh | - |
dc.contributor.googleauthor | Jun Chul Park | - |
dc.contributor.googleauthor | Sung Kwan Shin | - |
dc.contributor.googleauthor | Sang Kil Lee | - |
dc.contributor.googleauthor | Yong Chan Lee | - |
dc.identifier.doi | 10.3389/fmed.2021.722141 | - |
dc.contributor.localId | A01676 | - |
dc.contributor.localId | A02112 | - |
dc.contributor.localId | A02812 | - |
dc.contributor.localId | A02988 | - |
dc.contributor.localId | A06020 | - |
dc.contributor.localId | A03591 | - |
dc.contributor.localId | A05070 | - |
dc.relation.journalcode | J03762 | - |
dc.identifier.eissn | 2296-858X | - |
dc.identifier.pmid | 35118082 | - |
dc.subject.keyword | elderly | - |
dc.subject.keyword | endoscopic submucosal dissection | - |
dc.subject.keyword | esophageal cancer | - |
dc.subject.keyword | prognostic factors | - |
dc.subject.keyword | surgical resection | - |
dc.contributor.alternativeName | Park, Jun Chul | - |
dc.contributor.affiliatedAuthor | 박준철 | - |
dc.contributor.affiliatedAuthor | 신성관 | - |
dc.contributor.affiliatedAuthor | 이상길 | - |
dc.contributor.affiliatedAuthor | 이용찬 | - |
dc.contributor.affiliatedAuthor | 장진원 | - |
dc.contributor.affiliatedAuthor | 정다현 | - |
dc.contributor.affiliatedAuthor | 허철웅 | - |
dc.citation.volume | 8 | - |
dc.citation.startPage | 722141 | - |
dc.identifier.bibliographicCitation | FRONTIERS IN MEDICINE, Vol.8 : 722141, 2022-01 | - |
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