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Effect of systemic atherosclerosis on overactive bladder symptoms in men with benign prostatic hyperplasia

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dc.contributor.author구교철-
dc.contributor.author유정우-
dc.contributor.author이광석-
dc.date.accessioned2022-03-11T05:59:25Z-
dc.date.available2022-03-11T05:59:25Z-
dc.date.issued2022-01-
dc.identifier.issn1757-5664-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/187894-
dc.description.abstractObjective: Symptoms of male overactive bladder (OAB) may be caused by several systemic pathophysiological factors rather than a single-source etiology. We investigated the clinical factors associated with the severity of OAB symptoms in treatment-naïve men with coexisting benign prostatic hyperplasia. Methods: We obtained records from a health promotion center database of male patients who visited between March 2019 and February 2020. Men without a history of treatment for lower urinary tract symptoms were evaluated using the International Prostate Symptom Score (IPSS), Overactive Bladder Symptom Score, transrectal ultrasonography, medical history, and carotid duplex ultrasound for the evaluation of atherosclerosis. Benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS) was defined as an IPSS of eight points or higher. Patients with comorbidities that may affect their voiding function were excluded. Results: A total of 764 patients were divided into two groups based on their diagnosis: an OAB group and a non-OAB group. The non-OAB group consisted of 627 patients (82.1%) and the OAB group consisted of 137 patients (17.9%). Using multivariable analysis BPH/LUTS was identified as an independent risk factor for OAB. In the OAB group without BPH/LUTS, carotid atherosclerosis was significantly associated with the severity of OAB symptoms. A history of diabetes mellitus was the only variable that was associated with the severity of urinary urgency. Systolic blood pressure was associated with severity of urinary urgency in the OAB group with BPH/LUTS. Conclusions: Factors associated with male OAB exhibit different pathophysiology in the severity of symptoms depending on the presence of BPH/LUTS. Treatment for atherosclerosis and associated systemic pathophysiological factors could lower OAB symptom severity in male patients without BPH/LUTS.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherBlackwell Publishing Asia-
dc.relation.isPartOfLUTS-LOWER URINARY TRACT SYMPTOMS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAtherosclerosis*-
dc.subject.MESHHumans-
dc.subject.MESHLower Urinary Tract Symptoms* / epidemiology-
dc.subject.MESHLower Urinary Tract Symptoms* / etiology-
dc.subject.MESHMale-
dc.subject.MESHProstatic Hyperplasia* / complications-
dc.subject.MESHProstatic Hyperplasia* / epidemiology-
dc.subject.MESHUrinary Bladder, Overactive* / complications-
dc.subject.MESHUrination-
dc.titleEffect of systemic atherosclerosis on overactive bladder symptoms in men with benign prostatic hyperplasia-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Urology (비뇨의학교실)-
dc.contributor.googleauthorDongu Lee-
dc.contributor.googleauthorKyo Chul Koo-
dc.contributor.googleauthorJeong Woo Yoo-
dc.contributor.googleauthorKwang Suk Lee-
dc.identifier.doi10.1111/luts.12406-
dc.contributor.localIdA00188-
dc.contributor.localIdA06141-
dc.contributor.localIdA02668-
dc.relation.journalcodeJ03277-
dc.identifier.eissn1757-5672-
dc.identifier.pmid34323012-
dc.identifier.urlhttps://onlinelibrary.wiley.com/doi/10.1111/luts.12406-
dc.subject.keywordlower urinary tract symptom-
dc.subject.keywordmale-
dc.subject.keywordurination disorders-
dc.subject.keywordvoiding dysfunction-
dc.contributor.alternativeNameKoo, Kyo Chul-
dc.contributor.affiliatedAuthor구교철-
dc.contributor.affiliatedAuthor유정우-
dc.contributor.affiliatedAuthor이광석-
dc.citation.volume14-
dc.citation.number1-
dc.citation.startPage35-
dc.citation.endPage40-
dc.identifier.bibliographicCitationLUTS-LOWER URINARY TRACT SYMPTOMS, Vol.14(1) : 35-40, 2022-01-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers

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