Cited 2 times in
Apparent treatment-resistant hypertension among ambulatory hypertensive patients: a cross-sectional study from 13 general hospitals
DC Field | Value | Language |
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dc.contributor.author | 강석민 | - |
dc.date.accessioned | 2022-03-11T05:50:13Z | - |
dc.date.available | 2022-03-11T05:50:13Z | - |
dc.date.issued | 2021-07 | - |
dc.identifier.issn | 1226-3303 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/187823 | - |
dc.description.abstract | Background/aims: To examine the prevalence and clinical characteristics of apparent treatment-resistant hypertension among ambulatory hypertensive patients. Methods: We enrolled adult ambulatory hypertensive patients at 13 well-qualified general hospitals in Korea from January to June 2012. Apparent resistant hypertension was defined as an elevated blood pressure > 140/90 mmHg with the use of three antihypertensive agents, including diuretics, or ≥ 4 antihypertensives, regardless of the blood pressure. Controlled hypertension was defined as a blood pressure within the target using three antihypertensives, including diuretics. Results: Among 16,915 hypertensive patients, 1,172 (6.9%) had controlled hypertension, and 1,514 (8.9%) had apparent treatment-resistant hypertension. Patients with apparent treatment-resistant hypertension had an earlier onset of hypertension (56.8 years vs. 58.8 years, p = 0.007) and higher body mass index (26.3 kg/m2 vs. 24.9 kg/m2, p < 0.001) than those with controlled hypertension. Drug compliance did not differ between groups. In the multivariable analysis, earlier onset of hypertension (odds ratio [OR], 0.98; 95% confidence interval [CI], 0.97 to 0.99; p < 0.001) and the presence of comorbidities (OR, 2.06; 95% CI, 1.27 to 3.35; p < 0.001), such as diabetes mellitus, ischemic heart disease, heart failure, and chronic kidney disease, were independent predictors. Among the patients with apparent treatment-resistant hypertension, only 5.2% were receiving ≥ 2 antihypertensives at maximally tolerated doses. Conclusion: Apparent treatment-resistant hypertension prevalence is 8.9% among ambulatory hypertensive patients in Korea. An earlier onset of hypertension and the presence of comorbidities are independent predictors. Optimization of medical treatment may reduce the rate of apparent treatment-resistant hypertension. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Korean Association of Internal Medicine | - |
dc.relation.isPartOf | KOREAN JOURNAL OF INTERNAL MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Antihypertensive Agents / pharmacology | - |
dc.subject.MESH | Antihypertensive Agents / therapeutic use | - |
dc.subject.MESH | Blood Pressure | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Drug Resistance | - |
dc.subject.MESH | Hospitals, General* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypertension* / diagnosis | - |
dc.subject.MESH | Hypertension* / drug therapy | - |
dc.subject.MESH | Hypertension* / epidemiology | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Republic of Korea / epidemiology | - |
dc.title | Apparent treatment-resistant hypertension among ambulatory hypertensive patients: a cross-sectional study from 13 general hospitals | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Sehun Kim | - |
dc.contributor.googleauthor | Jin Joo Park | - |
dc.contributor.googleauthor | Mi-Seung Shin | - |
dc.contributor.googleauthor | Choong Hwan Kwak | - |
dc.contributor.googleauthor | Bong-Ryeol Lee | - |
dc.contributor.googleauthor | Sung-Ji Park | - |
dc.contributor.googleauthor | Hae-Young Lee | - |
dc.contributor.googleauthor | Sang-Hyun Kim | - |
dc.contributor.googleauthor | Seok-Min Kang | - |
dc.contributor.googleauthor | Byung-Su Yoo | - |
dc.contributor.googleauthor | Joong-Wha Chung | - |
dc.contributor.googleauthor | Si Wan Choi | - |
dc.contributor.googleauthor | Sang-Ho Jo | - |
dc.contributor.googleauthor | Jinho Shin | - |
dc.contributor.googleauthor | Dong-Ju Choi | - |
dc.identifier.doi | 10.3904/kjim.2019.361 | - |
dc.contributor.localId | A00037 | - |
dc.relation.journalcode | J02883 | - |
dc.identifier.eissn | 2005-6648 | - |
dc.identifier.pmid | 34092048 | - |
dc.subject.keyword | Apparent treatment resistant hypertension | - |
dc.subject.keyword | Characteristics | - |
dc.subject.keyword | Independent predictor | - |
dc.subject.keyword | Korea | - |
dc.subject.keyword | Prevalence | - |
dc.contributor.alternativeName | Kang, Seok Min | - |
dc.contributor.affiliatedAuthor | 강석민 | - |
dc.citation.volume | 36 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 888 | - |
dc.citation.endPage | 897 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF INTERNAL MEDICINE, Vol.36(4) : 888-897, 2021-07 | - |
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