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Thoracic skeletal muscle quantification using computed tomography and prognosis of elderly ICU patients

DC Field Value Language
dc.contributor.author김송이-
dc.contributor.author김영삼-
dc.contributor.author문성우-
dc.contributor.author박무석-
dc.contributor.author이수환-
dc.contributor.author임아영-
dc.contributor.author정경수-
dc.contributor.author최지수-
dc.date.accessioned2022-02-23T00:54:44Z-
dc.date.available2022-02-23T00:54:44Z-
dc.date.issued2021-12-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/187437-
dc.description.abstractIn elderly ICU patients, the prevalence of skeletal muscle loss is high. Longitudinal effect of thoracic muscles, especially in elderly ICU patients, are unclear although skeletal muscle loss is related with the short- and long-term outcomes. This study aimed to evaluate whether pectoralis muscle mass loss could be a predictor of prognosis in elderly ICU patients. We retrospectively evaluated 190 elderly (age > 70 years) patients admitted to the ICU. We measured the cross-sectional area (CSA) of the pectoralis muscle (PMCSA) at the fourth vertebral region. CT scans within two days before ICU admission were used for analysis. Mortality, prolonged mechanical ventilation, and longitudinal changes in Sequential Organ Failure Assessment (SOFA) scores were examined. PMCSA below median was significantly related with prolonged ventilation (odds ratio 2.92) and a higher SOFA scores during the ICU stay (estimated mean = 0.94). PMCSA below median was a significant risk for hospital mortality (hazards ratio 2.06). In elderly ICU patients, a low ICU admission PMCSA was associated with prolonged ventilation, higher SOFA score during the ICU stay, and higher mortality. Adding thoracic skeletal muscle CSA at the time of ICU admission into consideration in deciding the therapeutic intensity in elderly ICU patients may help in making medical decisions.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherNature Publishing Group-
dc.relation.isPartOfSCIENTIFIC REPORTS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHIntensive Care Units-
dc.subject.MESHMale-
dc.subject.MESHMuscle, Skeletal / physiopathology*-
dc.subject.MESHOrgan Dysfunction Scores-
dc.subject.MESHPrognosis-
dc.subject.MESHRespiration, Artificial / methods-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHThorax / physiopathology*-
dc.subject.MESHTomography, X-Ray Computed / methods-
dc.titleThoracic skeletal muscle quantification using computed tomography and prognosis of elderly ICU patients-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorSung Woo Moon-
dc.contributor.googleauthorSong Yee Kim-
dc.contributor.googleauthorJi Soo Choi-
dc.contributor.googleauthorAh Young Leem-
dc.contributor.googleauthorSu Hwan Lee-
dc.contributor.googleauthorMoo Suk Park-
dc.contributor.googleauthorYoung Sam Kim-
dc.contributor.googleauthorKyung Soo Chung-
dc.identifier.doi10.1038/s41598-021-02853-4-
dc.contributor.localIdA00626-
dc.contributor.localIdA00707-
dc.contributor.localIdA01363-
dc.contributor.localIdA01457-
dc.contributor.localIdA02904-
dc.contributor.localIdA03382-
dc.contributor.localIdA03570-
dc.contributor.localIdA05057-
dc.relation.journalcodeJ02646-
dc.identifier.eissn2045-2322-
dc.identifier.pmid34873225-
dc.contributor.alternativeNameKim, Song Yee-
dc.contributor.affiliatedAuthor김송이-
dc.contributor.affiliatedAuthor김영삼-
dc.contributor.affiliatedAuthor문성우-
dc.contributor.affiliatedAuthor박무석-
dc.contributor.affiliatedAuthor이수환-
dc.contributor.affiliatedAuthor임아영-
dc.contributor.affiliatedAuthor정경수-
dc.contributor.affiliatedAuthor최지수-
dc.citation.volume11-
dc.citation.number1-
dc.citation.startPage23461-
dc.identifier.bibliographicCitationSCIENTIFIC REPORTS, Vol.11(1) : 23461, 2021-12-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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