Cited 1 times in
Prognostic Value of Terminal Ileal Inflammation in Patients with Ulcerative Colitis
DC Field | Value | Language |
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dc.contributor.author | 강은애 | - |
dc.contributor.author | 김원호 | - |
dc.contributor.author | 김태일 | - |
dc.contributor.author | 박수정 | - |
dc.contributor.author | 박재준 | - |
dc.contributor.author | 박지혜 | - |
dc.contributor.author | 천재희 | - |
dc.contributor.author | 유종욱 | - |
dc.date.accessioned | 2021-12-28T17:49:27Z | - |
dc.date.available | 2021-12-28T17:49:27Z | - |
dc.date.issued | 2021-11 | - |
dc.identifier.issn | 1976-2283 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/187284 | - |
dc.description.abstract | Background/aims: Few studies have investigated terminal ileal lesions and their prognostic value in patients with ulcerative colitis (UC). We evaluated the clinical significance of these lesions as a prognostic factor in patients with UC who were in clinical remission. Methods: We retrospectively selected 567 of 4,066 colonoscopy reports that included positive findings from orificial observations of the terminal ileum (TI) and appendix in patients with UC. We finally recruited patients who were in clinical remission (n=204). We compared the clinical courses, including relapse and other prognostic parameters associated with UC, between the groups. Results: The baseline patient characteristics were not significantly different between patients with (n=69, TI+ group) and without TI lesions (n=135, TI- group), although there were more never-smokers in the TI+ group (n=57 [82.6%] in the TI+ group; n=86 [63.7%] in the TI- group; p=0.005). Of note, appendiceal orifice inflammation (AOI) was less frequently found in the TI+ group (14.5%) than in the TI- group (71.9%, p<0.001). The cumulative relapse rate was numerically higher in the TI- group, but it was not significantly different according to the Kaplan-Meier analysis (p=0.116). Multivariate Cox regression analysis also revealed advanced age at diagnosis as the most significant factor (adjusted hazard ratio, 0.964; 95% confidence interval, 0.932 to 0.998; p=0.037), but neither TI inflammation nor AOI were significantly associated with the cumulative relapse rate in patients with UC in clinical remission. Conclusions: For patients with UC in clinical remission, neither terminal ileal lesions nor AOI had significant clinical or predictive value for future relapse. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Editorial Office of Gut and Liver | - |
dc.relation.isPartOf | GUT AND LIVER | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Colitis, Ulcerative* / complications | - |
dc.subject.MESH | Colonoscopy | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Ileum | - |
dc.subject.MESH | Inflammation | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Recurrence | - |
dc.subject.MESH | Retrospective Studies | - |
dc.title | Prognostic Value of Terminal Ileal Inflammation in Patients with Ulcerative Colitis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Jongwook Yu | - |
dc.contributor.googleauthor | Jihye Park | - |
dc.contributor.googleauthor | Eun Ae Kang | - |
dc.contributor.googleauthor | Soo Jung Park | - |
dc.contributor.googleauthor | Jae Jun Park | - |
dc.contributor.googleauthor | Tae Il Kim | - |
dc.contributor.googleauthor | Won Ho Kim | - |
dc.contributor.googleauthor | Jae Hee Cheon | - |
dc.identifier.doi | 10.5009/gnl20294 | - |
dc.contributor.localId | A05966 | - |
dc.contributor.localId | A00774 | - |
dc.contributor.localId | A01079 | - |
dc.contributor.localId | A01539 | - |
dc.contributor.localId | A01636 | - |
dc.contributor.localId | A04575 | - |
dc.contributor.localId | A04030 | - |
dc.relation.journalcode | J00954 | - |
dc.identifier.eissn | 2005-1212 | - |
dc.identifier.pmid | 33767032 | - |
dc.subject.keyword | Appendix | - |
dc.subject.keyword | Ileum | - |
dc.subject.keyword | Inflammation | - |
dc.subject.keyword | Inflammatory bowel disease | - |
dc.subject.keyword | Ulcerative colitis | - |
dc.contributor.alternativeName | Kang, Eun Ae | - |
dc.contributor.affiliatedAuthor | 강은애 | - |
dc.contributor.affiliatedAuthor | 김원호 | - |
dc.contributor.affiliatedAuthor | 김태일 | - |
dc.contributor.affiliatedAuthor | 박수정 | - |
dc.contributor.affiliatedAuthor | 박재준 | - |
dc.contributor.affiliatedAuthor | 박지혜 | - |
dc.contributor.affiliatedAuthor | 천재희 | - |
dc.citation.volume | 15 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 858 | - |
dc.citation.endPage | 866 | - |
dc.identifier.bibliographicCitation | GUT AND LIVER, Vol.15(6) : 858-866, 2021-11 | - |
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