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Lymphovascular Invasion: Traditional but Vital and Sensible Prognostic Factor in Early Gastric Cancer
DC Field | Value | Language |
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dc.contributor.author | 김유민 | - |
dc.contributor.author | 김형일 | - |
dc.contributor.author | 송정호 | - |
dc.contributor.author | 이세진 | - |
dc.contributor.author | 조민아 | - |
dc.contributor.author | 최서희 | - |
dc.contributor.author | 형우진 | - |
dc.date.accessioned | 2021-12-28T17:45:14Z | - |
dc.date.available | 2021-12-28T17:45:14Z | - |
dc.date.issued | 2021-12 | - |
dc.identifier.issn | 1068-9265 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/187252 | - |
dc.description.abstract | Background: Although patients with early gastric cancer have good prognosis, recurrence after treatment may occur. Lymphovascular invasion (LVI) in gastric cancer has long been suggested as a poor prognostic indicator. This study sought to evaluate the prognostic effect of LVI in patients with early gastric cancer. Methods: From 2005 to 2016, 6516 patients with early gastric cancer who underwent radical gastrectomy were analyzed. The patients were categorized according to LVI and lymph node (LN) status. Results: LVI was present in 853 patients (13.1%). Patients with LVI or LN metastasis had more aggressive tumor characteristics than patients without both LVI and LN metastasis. The overall and relapse-free survival in patients with LVI were significantly worse than in patients without LVI. When we compared the survival rate of patients stratified by LVI and LN status, there was a significant overall and relapse-free survival difference between patients without both LVI and LN metastasis compared with those with LVI but without LN metastasis (p < 0.001). The overall and relapse-free survival of patients with LVI but without LN metastasis were similar to those without LVI but with LN metastasis (p = 0.818). Patients with LVI or LN metastasis showed a high frequency of recurrence (p < 0.001). Multivariate analysis showed that LVI and LN status were independent risk factors for relapse-free survival of early gastric cancer patients. Conclusions: Early gastric cancer with LVI is associated with poor prognosis and frequent recurrence. When predicting the prognosis of patients with early gastric cancer, LVI should be considered. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Springer | - |
dc.relation.isPartOf | ANNALS OF SURGICAL ONCOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Neoplasm Invasiveness / pathology | - |
dc.subject.MESH | Neoplasm Recurrence, Local / pathology | - |
dc.subject.MESH | Neoplasm Recurrence, Local / surgery | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Stomach Neoplasms* / pathology | - |
dc.subject.MESH | Stomach Neoplasms* / surgery | - |
dc.title | Lymphovascular Invasion: Traditional but Vital and Sensible Prognostic Factor in Early Gastric Cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.googleauthor | Seohee Choi | - |
dc.contributor.googleauthor | Jeong Ho Song | - |
dc.contributor.googleauthor | Sejin Lee | - |
dc.contributor.googleauthor | Minah Cho | - |
dc.contributor.googleauthor | Yoo Min Kim | - |
dc.contributor.googleauthor | Hyoung-Il Kim | - |
dc.contributor.googleauthor | Woo Jin Hyung | - |
dc.identifier.doi | 10.1245/s10434-021-10224-6 | - |
dc.contributor.localId | A00782 | - |
dc.contributor.localId | A01154 | - |
dc.contributor.localId | A04763 | - |
dc.contributor.localId | A05933 | - |
dc.contributor.localId | A05418 | - |
dc.contributor.localId | A05052 | - |
dc.contributor.localId | A04382 | - |
dc.relation.journalcode | J00179 | - |
dc.identifier.eissn | 1534-4681 | - |
dc.identifier.pmid | 34075484 | - |
dc.identifier.url | https://link.springer.com/article/10.1245%2Fs10434-021-10224-6 | - |
dc.contributor.alternativeName | Kim, Yoo Min | - |
dc.contributor.affiliatedAuthor | 김유민 | - |
dc.contributor.affiliatedAuthor | 김형일 | - |
dc.contributor.affiliatedAuthor | 송정호 | - |
dc.contributor.affiliatedAuthor | 이세진 | - |
dc.contributor.affiliatedAuthor | 조민아 | - |
dc.contributor.affiliatedAuthor | 최서희 | - |
dc.contributor.affiliatedAuthor | 형우진 | - |
dc.citation.volume | 28 | - |
dc.citation.number | 13 | - |
dc.citation.startPage | 8928 | - |
dc.citation.endPage | 8935 | - |
dc.identifier.bibliographicCitation | ANNALS OF SURGICAL ONCOLOGY, Vol.28(13) : 8928-8935, 2021-12 | - |
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